4,630 research outputs found
Digitization of LAr calorimeter for CSC simulations
This note describes the digitization of the LAr signals, which is the step creating RDO from Geant4 Hits, as used during the production of the CSC simulated samples with athena release 12
Issues in determining alpha_s from hadronic tau decay and electroproduction data
We discuss some key issues associated with duality-violating and
non-perturbative OPE contributions to the theoretical representations of light
quark current-current two-point functions and relevant to precision
determinations of alpha_s from hadronic tau decay and electroproduction
cross-section data. We demonstrate that analyses with an explicit
representation of duality-violating effects are required to bring theoretical
errors in such extractions under control, motivating the accompanying paper in
these proceedings, which presents the results of such an analysis.Comment: 5 pages, 4 figures. Prepared for the Proceedings of the International
Workshop on e+e- collisions from Phi to Psi (PHIPSI11), Sep. 19-22, 2011,
BINP, Novosibirsk, Russi
Breakdown of scale-invariance in the coarsening of phase-separating binary fluids
We present evidence, based on lattice Boltzmann simulations, to show that the
coarsening of the domains in phase separating binary fluids is not a
scale-invariant process. Moreover we emphasise that the pathway by which phase
separation occurs depends strongly on the relation between diffusive and
hydrodynamic time scales.Comment: 4 pages, Latex, 4 eps Figures included. (higher quality Figures can
be obtained from [email protected]
Subduction beneath Laurentia modified the eastern North American cratonic edge : Evidence from P wave and S wave tomography
Funding Information: NERC Doctoral Training Partnership: Science and Solutions for a Changing Planet and Leverhulme Trust Acknowledgments A.B. is funded by the NERC Doctoral Training Partnership: Science and Solutions for a Changing Planet. I.B. is funded by the Leverhulme Trust. F.D. acknowledges funding from NSERC through their Discovery grants and Canada Research Chairs program. We thank J. VanDecar for use of his tomographic inversion and MCCC codes. SAC [Helffrich et al., 2013] and GMT [Wessel and Smith, 1995] software were also used to process seismic data obtained from the IRIS DMC and from the Canadian National Data Centre (Natural Resources Canada). A digital supplement is also available to download containing models and the processed relative arrivalâtime data set, additional information is available from A.B. (email: [email protected]). Discussing the implications of our tomographic results with S. Goes and A. Hynes provided great motivation for this manuscript. Two anonymous reviewers helped clarify our interpretations.Peer reviewedPublisher PD
The Role of Intravitreal Corticosteroids in the Treatment of DME: Predictive OCT Biomarkers
Abstract: This work aims to summarize predictive biomarkers to guide treatment choice in DME.
Intravitreal anti-VEGF is considered the gold standard treatment for centers involving DME, while
intravitreal steroid treatment has been established as a second-line treatment in DME. However, more
than 1/3 of the patients do not adequately respond to anti-VEGF treatment despite up to 4-weekly
injections. Not surprisingly, insufficient response to anti-VEGF therapy has been linked to low-normal
VEGF levels in the serum and aqueous humor. These patients may well benefit from an early switch to
intravitreal steroid treatment. In these patients, morphological biomarkers visible in OCT may predict
treatment response and guide treatment decisions. Namely, the presence of a large amount of retinal
and choroidal hyperreflective foci, disruption of the outer retinal layers and other signs of chronicity
such as intraretinal cysts extending into the outer retina and a lower choroidal vascular index are all
signs suggestive of a favorable treatment response of steroids compared to anti-VEGF. This paper
summarizes predictive biomarkers in DME in order to assist individual treatment decisions in DME.
These markers will help to identify DME patients who may benefit from primary dexamethasone
treatment or an early switc
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