4,630 research outputs found

    Digitization of LAr calorimeter for CSC simulations

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    This note describes the digitization of the LAr signals, which is the step creating RDO from Geant4 Hits, as used during the production of the CSC simulated samples with athena release 12

    Issues in determining alpha_s from hadronic tau decay and electroproduction data

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    We discuss some key issues associated with duality-violating and non-perturbative OPE contributions to the theoretical representations of light quark current-current two-point functions and relevant to precision determinations of alpha_s from hadronic tau decay and electroproduction cross-section data. We demonstrate that analyses with an explicit representation of duality-violating effects are required to bring theoretical errors in such extractions under control, motivating the accompanying paper in these proceedings, which presents the results of such an analysis.Comment: 5 pages, 4 figures. Prepared for the Proceedings of the International Workshop on e+e- collisions from Phi to Psi (PHIPSI11), Sep. 19-22, 2011, BINP, Novosibirsk, Russi

    Breakdown of scale-invariance in the coarsening of phase-separating binary fluids

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    We present evidence, based on lattice Boltzmann simulations, to show that the coarsening of the domains in phase separating binary fluids is not a scale-invariant process. Moreover we emphasise that the pathway by which phase separation occurs depends strongly on the relation between diffusive and hydrodynamic time scales.Comment: 4 pages, Latex, 4 eps Figures included. (higher quality Figures can be obtained from [email protected]

    Subduction beneath Laurentia modified the eastern North American cratonic edge : Evidence from P wave and S wave tomography

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    Funding Information: NERC Doctoral Training Partnership: Science and Solutions for a Changing Planet and Leverhulme Trust Acknowledgments A.B. is funded by the NERC Doctoral Training Partnership: Science and Solutions for a Changing Planet. I.B. is funded by the Leverhulme Trust. F.D. acknowledges funding from NSERC through their Discovery grants and Canada Research Chairs program. We thank J. VanDecar for use of his tomographic inversion and MCCC codes. SAC [Helffrich et al., 2013] and GMT [Wessel and Smith, 1995] software were also used to process seismic data obtained from the IRIS DMC and from the Canadian National Data Centre (Natural Resources Canada). A digital supplement is also available to download containing models and the processed relative arrival‐time data set, additional information is available from A.B. (email: [email protected]). Discussing the implications of our tomographic results with S. Goes and A. Hynes provided great motivation for this manuscript. Two anonymous reviewers helped clarify our interpretations.Peer reviewedPublisher PD

    The Role of Intravitreal Corticosteroids in the Treatment of DME: Predictive OCT Biomarkers

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    Abstract: This work aims to summarize predictive biomarkers to guide treatment choice in DME. Intravitreal anti-VEGF is considered the gold standard treatment for centers involving DME, while intravitreal steroid treatment has been established as a second-line treatment in DME. However, more than 1/3 of the patients do not adequately respond to anti-VEGF treatment despite up to 4-weekly injections. Not surprisingly, insufficient response to anti-VEGF therapy has been linked to low-normal VEGF levels in the serum and aqueous humor. These patients may well benefit from an early switch to intravitreal steroid treatment. In these patients, morphological biomarkers visible in OCT may predict treatment response and guide treatment decisions. Namely, the presence of a large amount of retinal and choroidal hyperreflective foci, disruption of the outer retinal layers and other signs of chronicity such as intraretinal cysts extending into the outer retina and a lower choroidal vascular index are all signs suggestive of a favorable treatment response of steroids compared to anti-VEGF. This paper summarizes predictive biomarkers in DME in order to assist individual treatment decisions in DME. These markers will help to identify DME patients who may benefit from primary dexamethasone treatment or an early switc
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