17 research outputs found
Arterial Doppler waveform analysis detects more PAD patients in diabetes type 2 but is arterial Doppler waveform analysis standardized?
No full textInternational audienc
Exercise Oximetry and Laser Speckle Contrast Imaging to Assess Microvascular Function in Lower Extremity Peripheral Artery Disease
No full textInternational audienc
Exercise Oximetry and Laser Speckle Contrast Imaging to Assess Microvascular Function in Lower Extremity Peripheral Artery Disease
No full textFast atom bombardment mass spectrometry of Mycobacterial glycopeptidolipid antigens: Structural characterization by charge remote fragmentation
No full textThiol modified mycolic acids
No full textPatient serum antibodies to mycolic acids have the potential to be surrogate markers of active tuberculosis
(TB) when they can be distinguished from the ubiquitously present cross-reactive antibodies to
cholesterol. Mycolic acids are known to interact more strongly with antibodies present in the serum of
patients with active TB than in patients with latent TB or no TB. Examples of single stereoisomers of
mycolic acids with chain lengths corresponding to major homologues of those present in Mycobacterium
tuberculosis have now been synthesised with a sulfur substituent on the terminal position of the -chain;
initial studies have established that one of these binds to a gold electrode surface, offering the potential
to develop second generation sensors for diagnostic patient antibody detection.MMS and ADS wish to acknowledge support from the Government
of Iraq through the award of PhD studentships.http://www.elsevier.com/locate/chemphysliphb2017BiochemistryChemistr
Current knowledge on mycolic acids in Corynebacterium glutamicum and their relevance for biotechnological processes
No full textMycolic Acid Analysis by High-Performance Liquid Chromatography for Identification of Mycobacterium Species
No full textMycobacterium tuberculosis is the etiologic agent of tuberculosis and can be accurately detected by laboratories using commercial genetic tests. Nontuberculosis mycobacteria (NTM) causing other mycobacterioses can be difficult to identify. The identification processes are confounded by an increasing diversity of newly characterized NTM species. The ubiquitous nature of NTM, combined with their potential to be opportunistic pathogens in immunocompromised as well as nonimmunodeficient patients, further complicates the problem of their identification. Since clinical case management varies depending on the etiologic agent, laboratories must identify the species in a timely manner. However, only a few identification methods can detect the species diversity within the Mycobacterium genus. Over the last decade, high-performance liquid chromatography analysis of the mycolic acids has become an accepted method for identification of mycobacteria. In this review, we assess its development and usefulness as an identification technique for Mycobacterium species
Phospholipase D activity of Corynebacterium pseudotuberculosis (Corynebacterium ovis) and Corynebacterium ulcerans, a distinctive marker within the genus Corynebacterium
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