3,953 research outputs found

    Complete description of polarization effects in e^+e^- pair production by a photon in the field of a strong laser wave

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    We consider production of a e^+e^- pair by a high-energy photon in the field of a strong laser wave. A probability of this process for circularly or linearly polarized laser photons and for arbitrary polarization of all other particles is calculated. We obtain the complete set of functions which describe such a probability in a compact invariant form. Besides, we discuss in some detail the polarization effects in the kinematics relevant to the problem of electron-photon conversion at photon-photon and electron-photon colliders.Comment: 14 pages, 8 figure

    Body, brain, life for cognitive decline (BBL-CD): Protocol for a multidomain dementia risk reduction randomized controlled trial for subjective cognitive decline and mild cognitive impairment

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    This is the final version. Available from Dove Medical Press via the DOI in this record. Background: With no cure for dementia and the number of people living with the condition predicted to rapidly rise, there is an urgent need for dementia risk reduction and prevention interventions. Modifiable lifestyle risk factors have been identified as playing a major role in the development of dementia; hence, interventions addressing these risk factors represent a significant opportunity to reduce the number of people developing dementia. Relatively few interventions have been trialed in older participants with cognitive decline (secondary prevention). Objectives: This study evaluates the efficacy and feasibility of a multidomain lifestyle risk reduction intervention for people with subjective cognitive decline (SCD) and mild cognitive impairment (MCI). Methods: This study is an 8-week, two-arm, single-blind, randomized controlled trial (RCT) of a lifestyle modification program to reduce dementia risk. The active control group receives the following four online educational modules: dementia literacy and lifestyle risk, Mediterranean diet (MeDi), cognitive engagement and physical activity. The intervention group also completes the same educational modules but receives additional practical components including sessions with a dietitian, online brain training and sessions with an exercise physiologist to assist with lifestyle modification. Results: Primary outcome measures are cognition (The Alzheimer’s Disease Assessment Scale-Cognitive-Plus [ADAS-Cog-Plus]) and a composite lifestyle risk factor score for Alzheimer’s disease (Australian National University – Alzheimer’s Disease Risk Index [ANU-ADRI]). Secondary outcome measures are motivation to change lifestyle (Motivation to Change Lifestyle and Health Behaviour for Dementia Risk Reduction [MCLHB-DRR]) and health-related quality of life (36-item Short Form Health Survey [SF-36]). Feasibility will be determined through adherence to diet (Mediterranean Diet Adherence Screener [MEDAS] and Australian Recommended Food Score [ARFS]), cognitive engagement (BrainHQ-derived statistics) and physical activity interventions (physical activity calendars). Outcomes are measured at baseline, immediately post-intervention and at 3-and 6-month follow-up by researchers blind to group allocation. Discussion: If successful and feasible, secondary prevention lifestyle interventions could provide a targeted, cost-effective way to reduce the number of people with cognitive decline going on to develop Alzheimer’s disease (AD) and other dementias.Dementia Australia Research FoundationAustralian National UniversityDementia Collaborative Research CentreNHMRC Centre for Research Excellence in Cognitive Health, the Australian National UniversityNeuroscience Research Australia, University of New South WalesRoyal Commonwealth Societ

    A study of thin liquid sheet flows

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    This study was a theoretical and experimental investigation of thin liquid sheet flows in vacuum. A sheet flow created by a narrow slit of width, W, coalesces to a point at a distance, L, as a result of surface tension forces acting at the sheet edges. As the flow coalesces, the fluid accumulates in the sheet edges. The observed triangular shape of the sheet agrees with the calculated triangular result. Experimental results for L/W as a function of Weber number, We, agree with the calculated result, L/W = the sq. root of 8We. The edge cross sectional shape is found to oscillate from elliptic to 'cigar' like to 'peanut' like and then back to elliptic in the flow direction. A theoretical one-dimensional model was developed that yielded only elliptic solutions for the edge cross section. At the points where the elliptic shapes occur, there is agreement between theory and experiment

    Near-Infrared Polarimetric Adaptive Optics Observations of NGC 1068: A torus created by a hydromagnetic outflow wind

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    We present J' and K' imaging linear polarimetric adaptive optics observations of NGC 1068 using MMT-Pol on the 6.5-m MMT. These observations allow us to study the torus from a magnetohydrodynamical (MHD) framework. In a 0.5" (30 pc) aperture at K', we find that polarisation arising from the passage of radiation from the inner edge of the torus through magnetically aligned dust grains in the clumps is the dominant polarisation mechanism, with an intrinsic polarisation of 7.0%±\pm2.2%. This result yields a torus magnetic field strength in the range of 4-82 mG through paramagnetic alignment, and 13920+11^{+11}_{-20} mG through the Chandrasekhar-Fermi method. The measured position angle (P.A.) of polarisation at K' is found to be similar to the P.A. of the obscuring dusty component at few parsec scales using infrared interferometric techniques. We show that the constant component of the magnetic field is responsible for the alignment of the dust grains, and aligned with the torus axis onto the plane of the sky. Adopting this magnetic field configuration and the physical conditions of the clumps in the MHD outflow wind model, we estimate a mass outflow rate \le0.17 M_{\odot} yr1^{-1} at 0.4 pc from the central engine for those clumps showing near-infrared dichroism. The models used were able to create the torus in a timescale of \geq105^{5} yr with a rotational velocity of \leq1228 km s1^{-1} at 0.4 pc. We conclude that the evolution, morphology and kinematics of the torus in NGC 1068 can be explained within a MHD framework.Comment: 14 pages, 4 figures, Accepted by MNRA

    Domestic ventilation rates, indoor humidity and dust mite allergens : are our homes causing the asthma pandemic?

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    This paper is concerned with historical changes in domestic ventilation rates, relative humidity and the associated risk of house dust mite colonization. A controlled trial evaluated allergen and water vapour control measures on the level of house dust mite (HDM) Der p1 allergen and indoor humidity, concurrently with changes in lung function in 54 subjects who completed the protocol. Mechanical heat recovery ventilation units significantly reduced moisture content in the active group, while HDM allergen reservoirs in carpets and beds were reduced by circa 96%. Self reported health status confirmed a significant clinical improvement in the active group. The study can form the basis for assessing minimum winter ventilation rates that can suppress RH below the critical ambient equilibrium humidity of 60% and thus inhibit dust mite colonization and activity in temperate and maritime in' uenced climatic regions

    The Hubble Space Telescope Treasury Program on the Orion Nebula Cluster

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    The Hubble Space Telescope (HST) Treasury Program on the Orion Nebula Cluster has used 104 orbits of HST time to image the Great Orion Nebula region with the Advanced Camera for Surveys (ACS), the Wide-Field/Planetary Camera 2 (WFPC2) and the Near Infrared Camera and Multi Object Spectrograph (NICMOS) instruments in 11 filters ranging from the U-band to the H-band equivalent of HST. The program has been intended to perform the definitive study of the stellar component of the ONC at visible wavelengths, addressing key questions like the cluster IMF, age spread, mass accretion, binarity and cirumstellar disk evolution. The scanning pattern allowed to cover a contiguous field of approximately 600 square arcminutes with both ACS and WFPC2, with a typical exposure time of approximately 11 minutes per ACS filter, corresponding to a point source depth AB(F435W) = 25.8 and AB(F775W)=25.2 with 0.2 magnitudes of photometric error. We describe the observations, data reduction and data products, including images, source catalogs and tools for quick look preview. In particular, we provide ACS photometry for 3399 stars, most of them detected at multiple epochs, WFPC2 photometry for 1643 stars, 1021 of them detected in the U-band, and NICMOS JH photometry for 2116 stars. We summarize the early science results that have been presented in a number of papers. The final set of images and the photometric catalogs are publicly available through the archive as High Level Science Products at the STScI Multimission Archive hosted by the Space Telescope Science Institute.Comment: Accepted for publication on the Astrophysical Journal Supplement Series, March 27, 201

    The cost-effectiveness of radiofrequency ablation for treating patients with gastric antral vascular ectasia refractory to first line endoscopic therapy

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    OBJECTIVE: This economic evaluation aims to provide a preliminary assessment of the cost-effectiveness of radiofrequency ablation (RFA) compared with argon plasma coagulation (APC), when used to treat APC-refractory gastric antral vascular ectasia (GAVE) in symptomatic patients.METHODS: A Markov model was constructed to undertake a cost-utility analysis for adults with persistent symptoms secondary to GAVE refractory to first line endoscopic therapy. The economic evaluation was conducted from a UK NHS and personal social services (PSS) perspective, with a 20-year time horizon, comparing RFA with APC. Patients transfer between health states defined by haemoglobin level. The clinical effectiveness data were sourced from expert opinion, resource use and costs were reflective of the UK NHS and benefits were quantified using Quality Adjusted Life Years (QALYs) with utility weights taken from the literature. The primary output was the Incremental Cost-Effectiveness Ratio (ICER), expressed as cost per QALY gained.RESULTS: Over a lifetime time horizon, the base case ICER was £4,840 per QALY gained with an 82.2% chance that RFA was cost-effective at a threshold of £20,000 per QALY gained. The model estimated that implementing RFA would result in reductions in the need for intravenous iron, endoscopic intervention and requirement for blood transfusions by 27.1%, 32.3% and 36.5% respectively. Compared to APC, RFA was associated with an estimated 36.7% fewer procedures.CONCLUSIONS: RFA treatment is likely to be cost-effective for patients with ongoing symptoms following failure of first line therapy with APC and could lead to substantive reductions in health care resource
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