8,996 research outputs found
Dental erosion: In vitro model of wine assessor's erosion
The document attached has been archived with permission from the Australian Dental Association. An external link to the publisher’s copy is included.Background: Wine makers and assessors frequently experience severe dental erosion. The objectives of this study were to develop an in vitro model of dental erosion caused by frequent wine contact with teeth, and to use this model to assess the effectiveness of a variety of methods which might protect against this form of erosion. Methods: An initial pilot study found that riesling style wine was more erosive than champagne style, and both more than claret. Wine tasting was simulated by subjecting exposed windows of enamel and root surfaces on 50 intact, extracted human teeth to 1400 one minute exposures to white wine (pH 3.2). A variety of dental materials were applied to the exposed windows on groups of teeth prior to erosive challenge, to assess their protective ability. Results: Protective resin coatings and fluoride varnishes protected both enamel and roots against wine induced erosion. A high degree of protection was provided by APF gel, with less by NaF gel. Conclusions: It was concluded that dentists may be able to help minimise erosion resulting from frequent wine-tasting in their patients by the clinical application of one or a combination of these agents at times prior to prolonged assessment periods.Tong Bee Mok, J McIntyre and D Hun
Teaching Physics Using Virtual Reality
We present an investigation of game-like simulations for physics teaching. We
report on the effectiveness of the interactive simulation "Real Time
Relativity" for learning special relativity. We argue that the simulation not
only enhances traditional learning, but also enables new types of learning that
challenge the traditional curriculum. The lessons drawn from this work are
being applied to the development of a simulation for enhancing the learning of
quantum mechanics
Visible and near infrared spectroscopy of Hayabusa re-entry using semi-autonomous tracking
A ground-based tracking camera and co-aligned slit-less spectrograph were used to measure the spectral signature of visible radiation emitted from the Hayabusa capsule as it entered into the Earth's atmosphere in June 2010. Good quality spectra were obtained that showed the presence of radiation from the heat shield of the vehicle and the shock-heated air in front of the vehicle. An analysis of the black body nature of the radiation concluded that the peak average temperature of the surface was about (3100±100) K
The Interaction between the ISM and Star Formation in the Dwarf Starburst Galaxy NGC 4214
We present the first interferometric study of the molecular gas in the
metal-poor dwarf starburst galaxy NGC 4214. Our map of the 12CO(1-0) emission,
obtained at the OVRO millimeter array, reveals an unexpected structural wealth.
We detected three regions of molecular emission in the north-west (NW),
south-east (SE) and centre of NGC 4214 which are in very different and distinct
evolutionary stages (total molecular mass: 5.1 x 10^6 M_sun). These differences
are apparent most dramatically when the CO morphologies are compared to optical
ground based and HST imaging: massive star formation has not started yet in the
NW region; the well-known starburst in the centre is the most evolved and star
formation in the SE complex started more recently. We derive a star formation
efficiency of 8% for the SE complex. Using high--resolution VLA observations of
neutral hydrogen HI and our CO data we generated a total gas column density map
for NGC 4214 (HI + H_2). No clear correlation is seen between the peaks of HI,
CO and the sites of ongoing star formation. This emphasizes the irregular
nature of dwarf galaxies. The HI and CO velocities agree well, so do the
H-alpha velocities. In total, we cataloged 14 molecular clumps in NGC 4214. Our
results from a virial mass analysis are compatible with a Galactic CO-to-H_2
conversion factor for NGC 4214 (lower than what is usually found in metal-poor
dwarf galaxies).Comment: accepted for publication in the AJ (February 2001), full ps file at:
ftp://ftp.astro.caltech.edu/users/fw/ngc4214/walter_prep.p
Long-range ferromagnetism of Mn12 acetate single-molecule magnets under a transverse magnetic field
We use neutron diffraction to probe the magnetization components of a crystal
of Mn12 single-molecule magnets. Each of these molecules behaves, at low
temperatures, as a nanomagnet with spin S = 10 and strong anisotropy along the
crystallographic c axis. Application of a magnetic field perpendicular to c
induces quantum tunneling between opposite spin orientations, enabling the
spins to attain thermal equilibrium. Below approximately 0.9 K, intermolecular
interactions turn this equilibrium state into a ferromagnetically ordered
phase. However, long range ferromagnetic correlations nearly disappear for
fields larger 5.5 T, possibly suggesting the existence of a quantum critical
point.Comment: 4 pages, 4 figure
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Alteration and Oxidiation of an Olivine Lamprophyre Dike from Southern Utah, USA: An Analog for Mars
We report on oxidized basaltic dike intrusions on the Colorado Plateau as analog for Martian basalt oxidation
Allosteric modulation of beta1 integrin function induces lung repair in animal model of emphysema.
Emphysema is a progressive lung disease characterised by loss of lung parenchyma with associated functional changes including decreased tissue elastance. Here we report beta1 integrin is a novel target for tissue repair and regeneration in emphysema. We show a single dose of a monoclonal antibody against beta1 integrin induced both functional and structural reversal of elastase-induced lung injury in vivo, and we found that similar matrix remodelling changes occurred in human lung tissue. We also identified a potential mechanism of action as this allosteric modulation of beta1 integrin inhibited elastase-induced caspase activation, F-actin aggregate formation and changes in cellular ATP levels. This was accompanied by maintenance of beta1?integrin levels and inhibition of caveolin-1 phosphorylation. We propose that allosteric modulation of beta1 integrin-mediated mechanosensing prevents cell death associated with lung injury and progressive emphysema, thus allowing cells to survive and for repair and regeneration to ensue
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