1,828 research outputs found
Mastery Learning: Improving the Model
In this paper, we report on developments in the Mastery Learning (ML) curriculum and assessment model that has been successfully implemented in a metropolitan university for teaching first-year mathematics. Initial responses to ML were positive; however, we ask whether the nature of the ML tests encourages a focus on shallow learning of procedures, and whether the structure of the assessment regime provides sufficient motivation for learning more complex problem solving. We analysed assessment data, as well as student reports and survey responses in an attempt to answer these questions
Ubiquitin carboxyl-terminal hydrolases are required for period maintenance of the circadian clock at high temperature in Arabidopsis
Protein ubiquitylation participates in a number of essential cellular processes including signal transduction and transcription, often by initiating the degradation of specific substrates through the 26S proteasome. Within the ubiquitin-proteasome system, deubiquitylating enzymes (DUBs) not only help generate and maintain the supply of free ubiquitin monomers, they also directly control functions and activities of specific target proteins by modulating the pool of ubiquitylated species. Ubiquitin carboxyl-terminal hydrolases (UCHs) belong to an enzymatic subclass of DUBs, and are represented by three members in Arabidopsis, UCH1, UCH2 and UCH3. UCH1 and UCH2 influence auxin-dependent developmental pathways in Arabidopsis through their deubiquitylation activities, whereas biological and enzymatic functions of UCH3 remain unclear. Here, we demonstrate that Arabidopsis UCH3 acts to maintain the period of the circadian clock at high temperatures redundantly with UCH1 and UCH2. Whereas single uch1, uch2 and uch3 mutants have weak circadian phenotypes, the triple uch mutant displays a drastic lengthening of period at high temperatures that is more extreme than the uch1 uch2 double mutant. UCH3 also possesses a broad deubiquitylation activity against a range of substrates that link ubiquitin via peptide and isopeptide linkages. While the protein target(s) of UCH1-3 are not yet known, we propose that these DUBs act on one or more factors that control period length of the circadian clock through removal of their bound ubiquitin moieties, thus ensuring that the clock oscillates with a proper period even at elevated temperature
The Influence of in-medium NN cross-sections, symmetry potential and impact parameter on the isospin observables
We explore the influence of in-medium nucleon-nucleon cross section, symmetry
potential and impact parameter on isospin sensitive observables in
intermediate-energy heavy-ion collisions with the ImQMD05 code, a modified
version of Quantum Molecular Dynamics model. At incident velocities above the
Fermi velocity, we find that the density dependence of symmetry potential plays
a more important role on the double neutron to proton ratio and the
isospin transport ratio than the in-medium nucleon-nucleon cross
sections, provided that the latter are constrained to a fixed total NN
collision rate. We also explore both and as a function of the
impact parameter. Since the copious production of intermediate mass fragments
is a distinguishing feature of intermediate-energy heavy-ion collisions, we
examine the isospin transport ratios constructed from different groups of
fragments. We find that the values of the isospin transport ratios for
projectile rapidity fragments with are greater than those constructed
from the entire projectile rapidity source. We believe experimental
investigations of this phenomenon can be performed. These may provide
significant tests of fragmentation time scales predicted by ImQMD calculations.Comment: 24 pages, 9 figures, to be published in Phys. Rev.
Online identities In and around organizations:a critical exploration and way forward
The construction, performance, and regulation of identities in the online world have deep implications for individuals, organizations, and society, particularly as digital technologies become increasingly omnipresent in our daily lives. In the last decades, analyses of online identities’ processes have moved from the exploration of identity play, through identity performance, toward a growing identity regulation through algorithmic management and the monetization of personal data. Despite a significant tradition of critical management and organization studies literature on identity, online identities have to date received only scant attention. This Special Issue explores what critical management and organization studies can contribute to research on online identities. Drawing on empirical analysis of virtual forums, social media, and platforms, the six papers included here highlight the struggles that accompany identity processes in the online environment and their implications for workers, activists, and other organized selves. In this introduction, we contextualize these contributions with reference to online identities studies and metaphors of the internet as a place, a tool, and a way of being. We comment on the contributions they make relating to the role of the body, and individual and collective dynamics in online identities processes. Following this, we propose critical ways forward concerning new forms of digital work, multiphrenic context collapse, and online references and sources of identity. We invite researchers to not only critically explore but also to engage with this brave new world that increasingly shapes our individual and collective selves
The use of conspicuity aids by cyclists and risk of crashes involving other road users: a protocol for a population based case-control study
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