Forced oscillations dynamic tribometer with real-time insights of lubricated interfaces

This paper presents an innovative forced oscillations dynamic tribometer, the CHRONOS tribometer, with a lubricated ball-on-flat contact configuration fitted out with an in situ optical visualization system and a triggered high-speed camera. The CHRONOS tribometer generates controlled oscillating kinematics by means of a shaker with a range of strokes from 5 μm to 2.5 mm and an oscillation frequency which can be adjusted from 5 Hz to 250 Hz. Displacement and velocity are measured using a vibrometer. The ball-on-flat mean contact pressure is set between 200 MPa and 600 MPa. During motion, the instantaneous normal and friction forces and the interfacial film thickness distribution (in the nanometer scale) are simultaneously measured. In addition to this instantaneous approach, a more macroscopic approach is developed in terms of moving averages of friction and velocity. Another parameter, the friction-velocity tilt angle, is also introduced. This last parameter may give information on the friction-velocity dependence. Eventually, the experiments performed on the CHRONOS device lead to the representation of synchronized temporal signals of displacement/velocity, friction, and lubricant central film thickness. This superimposition of key parameters reveals time effects introduced by the periodical fluid squeeze and flow in the contact

IJTC2007-44273 DRAINAGE OF A WETTING LIQUID: SLIP EFFECT OR MOLECULARLY ORGANISED LAYERS?

ABSTRACT A Surface Force Apparatus has been used to investigate the drainage of a blend of copolymer viscosity improver additive molecules in a base oil. A quasi-static squeeze of the interface is used to characterize the first repulsion layer and the confined adsorbed layer. Moreover, dynamical measurements enlighten a significant negative value of the immobile layer thickness (-50 nm). The occurrence of slip at the wall that may result in such effect, is discussed in terms of liquid-solid interface wettability, surface roughness and cleanliness, and friction experiments. As a consequence, a modeling of the interface consisting of two layers of different viscosity is proposed. This model of interfacial molecular organization allows us to explain the drainage behaviour of the wetting liquid

Pattern Analysis of Microtubule-Polymerizing and -Depolymerizing Agent Combinations as Cancer Chemotherapies

Subcellular distribution of mass can be analyzed by a technique that involves culturing cells on interferometers and digitizing their interference contours. Contour sampling resulted in 102 variables per cell, which were predictors of oncogenic transformation. Cell phenotypes can be deconstructed by use of latent factors, which represent the covariance of the real variables. The reversal of the cancertype phenotype by a combination of microtubule- stabilizing and -depolymerizing agents was described previously. The implications of these results have been explored by clinicians who treated patients with the combination of docetaxel and vinorelbine (Navelbine®). The current study was performed to determine the effects of different combinations on phenotype and in phases of the cell cycle other than mitosis. Combinations of paclitaxel with either colchicine, podophyllotoxin, nocodazole, or vinblastine caused phenotype reversal. Paclitaxel analogue, 7-deoxytaxol, by itself caused reversal. Factors #4, (filopodia), #5 (displacement and/or deep invaginations in the periphery), #8, and #12 took on values typical of normal cells, whereas the values of #7 (p21-activated kinase), and #13 (rounding up) shifted toward the cancer-type. All combinations altered microtubule arrangement at the cell edge. Delivery schedules and drug ratios used in clinical studies were subjected to analysis. Clinical response rates were better when the combination was not interspersed with a single agent (P=0.004). The results support the idea that efficacy depends upon simultaneous exposure to both agents, and suggest a novel mechanism for combination therapies. These therapies appear to restore in transformed cells some of the features of a contact-inhibited cell, and to impede progress through the cell cycle even when provided at nanomolar concentrations

The Current State of Performance Appraisal Research and Practice: Concerns, Directions, and Implications

On the surface, it is not readily apparent how some performance appraisal research issues inform performance appraisal practice. Because performance appraisal is an applied topic, it is useful to periodically consider the current state of performance research and its relation to performance appraisal practice. This review examines the performance appraisal literature published in both academic and practitioner outlets between 1985 and 1990, briefly discusses the current state of performance appraisal practice, highlights the juxtaposition of research and practice, and suggests directions for further research

Links between energy dissipation and wear mechanisms in solid epoxy/epoxy sliding contact

This paper covers wear and energy dissipation of solid epoxy induced by the alternative rubbing between two samples of identical thermosetting polymer. Varying normal load, sliding velocity and sliding distance, the authors were able to define and discuss wear and friction laws and associated energy dissipation. Moreover, traces of several wear mechanisms were distinguished on the worn surfaces and associated with applied conditions. Observed under higher velocity, polymer softening and local state transition were explained by surface temperature estimate and confirmed by infra-red spectroscopy measurements. To conclude this study, all observed phenomena are classified into two wear scenarios according to sliding velocity. © 2014 Elsevier Ltd

An Interfacial Friction Law for a Circular EHL Contact Under Free Sliding Oscillating Motion

International audienceThe friction response of a lubricated interface under free sliding oscillating motion is investigated as a function of the contact pressure and the rheology of the lubricant in terms of viscosity and piezoviscosity. For loaded contacts, both velocity dependent friction, referred to as viscous damping, and friction independent of the instantaneous sliding velocity contribute to the energy dissipation. Viscous damping mainly corresponds to the dissipation in the lubricant meniscus surrounding the contact, while dissipation within the confined lubricated interface is mainly independent of the instantaneous sliding velocity. The friction coefficient independent of the instantaneous sliding velocity falls on a master curve for the wide range of tested operating conditions and lubricant rheological properties. The master curve is a logarithmic function of a dimensionless parameter corresponding to the ratio of the viscosity of the confined lubricant to the product of the pressure and a characteristic time. The physical meaning of this latter and the friction law are discussed considering the confined interface as a viscoelastic fluid or a non-Newtonian Eyring fluid

Et au milieu coule le St Laurent. Géohistoire du rapport ville/cours d'eau dans les agglomérations de Québec et Lévis (Canada)

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The application of arti cial radionuclides from Nagasaki A-bomb as a global transport tracer at Canadian Arctic Ice Caps

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