AN ASSESSMENT OF WORKAROUNDS FOR SPATIAL EFFECTS IN THE CASE OF BINARY PROBIT

The consequences of spatial effects on discrete choice models have not been well established. Various ad hoc workarounds have been proposed to mitigate potential estimation problems. This paper employs Monte Carlo simulation to investigate the severity of the problems introduced by spatial effects and the effectiveness of the workarounds.Research Methods/ Statistical Methods,

Finger-Tip Injuries

Finger-tip injuries are among the most common injuries which have to be dealt with in emergency departments.They present a variety of problems which can be treated in different ways. This paper will present a variety of these injuries and discuss the treatment of each of them

Fractal Properties of the Distribution of Earthquake Hypocenters

We investigate a recent suggestion that the spatial distribution of earthquake hypocenters makes a fractal set with a structure and fractal dimensionality close to those of the backbone of critical percolation clusters, by analyzing four different sets of data for the hypocenter distributions and calculating the dynamical properties of the geometrical distribution such as the spectral dimension $d_s$. We find that the value of $d_s$ is consistent with that of the backbone, thus supporting further the identification of the hypocenter distribution as having the structure of the percolation backbone.Comment: 11 pages, LaTeX, HLRZ 68/9

A multi-data source surveillance system to detect a bioterrorism attack during the G8 summit in Scotland

In 18 weeks, Health Protection Scotland (HPS) deployed a syndromic surveillance system to early-detect natural or intentional disease outbreaks during the G8 Summit 2005 at Gleneagles, Scotland. The system integrated clinical and non-clinical datasets. Clinical datasets included Accident and Emergency (A and E) syndromes, and General Practice (GPs) codes grouped into syndromes. Non-clinical data included telephone calls to a nurse helpline, laboratory test orders, and hotel staff absenteeism. A cumulative sum-based detection algorithm and a log-linear regression model identified signals in the data. The system had a fax-based track for real-time identification of unusual presentations. Ninety-five signals were triggered by the detection algorithms and four forms were faxed to HPS. Thirteen signals were investigated. The system successfully complemented a traditional surveillance system in identifying a small cluster of gastroenteritis among the police force and triggered interventions to prevent further cases

Anisotropy beta functions

The flow of couplings under anisotropic scaling of momenta is computed in $\phi^3$ theory in 6 dimensions. It is shown that the coupling decreases as momenta of two of the particles become large, keeping the third momentum fixed, but at a slower rate than the decrease of the coupling if all three momenta become large simultaneously. This effect serves as a simple test of effective theories of high energy scattering, since such theories should reproduce these deviations from the usual logarithmic scale dependence.Comment: uuencoded ps file, 6 page

A review of modular strategies and architecture within manufacturing operations

This paper reviews existing modularity and modularization literature within manufacturing operations. Its purpose is to examine the tools, techniques, and concepts relating to modular production, to draw together key issues currently dominating the literature, to assess managerial implications associated with the emerging modular paradigm, and to present an agenda for future research directions. The review is based on journal papers included in the ABI/Inform electronic database and other noteworthy research published as part of significant research programmes. The research methodology concerns reviewing existing literature to identify key modular concepts, to determine modular developments, and to present a review of significant contributions to the field. The findings indicate that the modular paradigm is being adopted in a number of manufacturing organizations. As a result a range of conceptual tools, techniques, and frameworks has emerged and the field of modular enquiry is in the process of codifying the modular lexicon and developing appropriate modular strategies commensurate with the needs of manufacturers. Modular strategies and modular architecture were identified as two key issues currently dominating the modular landscape. Based on this review, the present authors suggest that future research areas need to focus on the development and subsequent standardization of interface protocols, cross-brand module use, supply chain power, transparency, and trust. This is the first review of the modular landscape and as such provides insights into, first, the development of modularization and, second, issues relating to designing modular products and modular supply chains

Scotin, a novel p53-inducible proapoptotic protein located in the ER and the nuclear membrane

p53 is a transcription factor that induces growth arrest or apoptosis in response to cellular stress. To identify new p53-inducible proapoptotic genes, we compared, by differential display, the expression of genes in spleen or thymus of normal and p53 nullizygote mice after γ-irradiation of whole animals. We report the identification and characterization of human and mouse Scotin homologues, a novel gene directly transactivated by p53. The Scotin protein is localized to the ER and the nuclear membrane. Scotin can induce apoptosis in a caspase-dependent manner. Inhibition of endogenous Scotin expression increases resistance to p53-dependent apoptosis induced by DNA damage, suggesting that Scotin plays a role in p53-dependent apoptosis. The discovery of Scotin brings to light a role of the ER in p53-dependent apoptosis

A Discrete and Bounded Envy-free Cake Cutting Protocol for Four Agents

We consider the well-studied cake cutting problem in which the goal is to identify a fair allocation based on a minimal number of queries from the agents. The problem has attracted considerable attention within various branches of computer science, mathematics, and economics. Although, the elegant Selfridge-Conway envy-free protocol for three agents has been known since 1960, it has been a major open problem for the last fifty years to obtain a bounded envy-free protocol for more than three agents. We propose a discrete and bounded envy-free protocol for four agents