194 research outputs found
Effects of Minijets on Hadronic Spectra and Azimuthal Harmonics in Au-Au Collisions at 200 GeV
The production of hadrons in heavy-ion collisions at RHIC in the low
transverse-momentum () region is investigated in the recombination model
with emphasis on the effects of minijets on the azimuthal anisotropy. Since the
study is mainly on the hadronization of partons at late time, the fluid picture
is not used to trace the evolution of the system. The inclusive distributions
at low are determined as the recombination products of thermal partons.
The dependencies of both pion and proton have a common exponential factor
apart from other dissimilar kinematic and resonance factors, because they are
inherited from the same pool of thermal partons. Instead of the usual
description based on hydrodynamics, the azimuthal anisotropy of the produced
hadrons is explained as the consequence of the effects of minijets, either
indirectly through the recombination of enhanced thermal partons in the
vicinity of the trajectories of the semihard partons, or directly through
thermal-shower recombination. Although our investigation is focussed on the
single-particle distribution at midrapidity, we give reasons why a component in
that distribution can be identified with the ridge, which together with the
second harmonic is due to the semihard partons created near the medium
surface that lead to calculable anisotropy in . It is shown that the
higher azimuthal harmonics, , can also be well reproduced without
reference to flow. The and centrality dependencies of the higher
harmonics are prescribed by the interplay between TT and TS recombination
components. The implication of the success of this drastic departure from the
conventional approach is discussed.Comment: 28 pages and 8 figures, more discussions and references adde
Distensibility of Small Pulmonary Blood Vessels 1
Although vasomotor activity in small pulmonary vessels has been studied extensively in the past, using the concept of resistance to flow, information on the distensibility of these vessels is very sparse. In Introduction The concept of resistance to flow has been extensively used in the past to study vasomotion in the pulmonary vascular bed of man and animals. These previous studies have provided useful information on the responses of the small pulmonary vessels (i.e., pulmonary "resistance" vessels) in various disease states and/or during administration of various drug
Refractive index tomography of turbid media by bifocal optical coherence refractometry
We demonstrate tomographic imaging of the refractive index of turbid media using bifocal optical coherence refractometry (BOCR). The technique, which is a variant of optical coherence tomography, is based on the measurement of the optical pathlength difference between two foci simultaneously present in a medium of interest. We describe a new method to axially shift the bifocal optical pathlength that avoids the need to physically relocate the objective lens or the sample during an axial scan, and present an experimental realization based on an adaptive liquid-crystal lens. We present experimental results, including video clips, which demonstrate refractive index tomography of a range of turbid liquid phantoms, as well as of human skin in vivo.<br /
Expert review document part 2: Methodology, terminology and clinical applications of optical coherence tomography for the assessment of interventional procedures
Optics and Quantum Electronics
Contains table of contents for Section 3 and reports on twenty research projects.Charles S. Draper Laboratories Contract DL-H-467138Joint Services Electronics Program Contract DAAL03-92-C-0001Joint Services Electronics Program Grant DAAH04-95-1-0038U.S. Air Force - Office of Scientific Research Contract F49620-91-C-0091MIT Lincoln LaboratoryNational Science Foundation Grant ECS 90-12787Fujitsu LaboratoriesNational Center for Integrated PhotonicsHoneywell Technology CenterU.S. Navy - Office of Naval Research (MFEL) Contract N00014-94-1-0717U.S. Navy - Office of Naval Research (MFEL) Grant N00014-91-J-1956National Institutes of Health Grant NIH-5-R01-GM35459-09U.S. Air Force - Office of Scientific Research Grant F49620-93-1-0301MIT Lincoln Laboratory Contract BX-5098Electric Power Research Institute Contract RP3170-25ENEC
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Development of a Primary Human Co-Culture Model of Inflamed Airway Mucosa
Neutrophil breach of the mucosal surface is a common pathological consequence of infection. We present an advanced co-culture model to explore neutrophil transepithelial migration utilizing airway mucosal barriers differentiated from primary human airway basal cells and examined by advanced imaging. Human airway basal cells were differentiated and cultured at air-liquid interface (ALI) on the underside of 3 µm pore-sized transwells, compatible with the study of transmigrating neutrophils. Inverted ALIs exhibit beating cilia and mucus production, consistent with conventional ALIs, as visualized by micro-optical coherence tomography (µOCT). µOCT is a recently developed imaging modality with the capacity for real time two- and three-dimensional analysis of cellular events in marked detail, including neutrophil transmigratory dynamics. Further, the newly devised and imaged primary co-culture model recapitulates key molecular mechanisms that underlie bacteria-induced neutrophil transepithelial migration previously characterized using cell line-based models. Neutrophils respond to imposed chemotactic gradients, and migrate in response to Pseudomonas aeruginosa infection of primary ALI barriers through a hepoxilin A3-directed mechanism. This primary cell-based co-culture system combined with µOCT imaging offers significant opportunity to probe, in great detail, micro-anatomical and mechanistic features of bacteria-induced neutrophil transepithelial migration and other important immunological and physiological processes at the mucosal surface
Method for Quantitative Study of Airway Functional Microanatomy Using Micro-Optical Coherence Tomography
We demonstrate the use of a high resolution form of optical coherence tomography, termed micro-OCT (μOCT), for investigating the functional microanatomy of airway epithelia. μOCT captures several key parameters governing the function of the airway surface (airway surface liquid depth, periciliary liquid depth, ciliary function including beat frequency, and mucociliary transport rate) from the same series of images and without exogenous particles or labels, enabling non-invasive study of dynamic phenomena. Additionally, the high resolution of μOCT reveals distinguishable phases of the ciliary stroke pattern and glandular extrusion. Images and functional measurements from primary human bronchial epithelial cell cultures and excised tissue are presented and compared with measurements using existing gold standard methods. Active secretion from mucus glands in tissue, a key parameter of epithelial function, was also observed and quantified
Optical coherence tomography—current technology and applications in clinical and biomedical research
Optics and Quantum Electronics
Contains table of contents for Section 3, reports on twenty-one research projects and a list of publications and meeting papers.Joint Services Electronics Program Contract DAAL03-92-C-0001U.S. Air Force - Office of Scientific Research Contract F49620-91-C-0091Charles S. Draper Laboratories Contract DL-H-441692MIT Lincoln LaboratoryNational Science Foundation Grant ECS 90-12787Fujitsu LaboratoriesU.S. Navy - Office of Naval Research Grant N00014-92-J-1302National Center for Integrated Photonic TechnologyNational Science Foundation Grant ECS 85-52701U.S. Navy - Office of Naval Research (MFEL) Grant N00014-91-C-0084U.S. Navy - Office of Naval Research (MFEL) Grant N00014-91-J-1956National Institutes of Health Grant R01-GM35459-08U.S. Air Force - Office of Scientific Research Grant F49620-93-1-0301MIT Lincoln Laboratory Contract BX-5098Electric Power Research Institute Contract RP3170-2
Optics and Quantum Electronics
Contains table of contents for Section 3 and reports on eighteen research projects.Defense Advanced Research Projects Agency/MIT Lincoln Laboratory Contract MDA972-92-J-1038Joint Services Electronics Program Grant DAAH04-95-1-0038National Science Foundation Grant ECS 94-23737U.S. Air Force - Office of Scientific Research Contract F49620-95-1-0221U.S. Navy - Office of Naval Research Grant N00014-95-1-0715MIT Center for Material Science and EngineeringNational Center for Integrated Photonics Technology Contract DMR 94-00334National Center for Integrated Photonics TechnologyU.S. Navy - Office of Naval Research (MFEL) Contract N00014-94-1-0717National Institutes of Health Grant 9-R01-EY11289MIT Lincoln Laboratory Contract BX-5098Electric Power Research Institute Contract RP3170-25ENEC
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