4,245 research outputs found
Analytical investigation of the effects of blade flexibility, unsteady aerodynamics, and variable inflow on helicopter rotor stall characteristics
Analytical investigation of effects of blade flexibility, unsteady aerodynamics, and variable inflow on helicopter rotor stall characteristic
Experimental investigation of model variable-geometry and ogee tip rotors
An experimental investigation was conducted to systematically explore the effects of inter-blade spatial relationships and pitch variations on rotor performance and wake geometry. Variable-geometry rotors consisting of various combinations of blade length, axial spacing, azimuth spacing, and collective pitch were tested at model scale in hover and forward flight. In addition, a hover test of a model rotor with an ogee blade tip design was conducted to determine its performance and wake characteristics. The results of this investigation indicate that properly selected variable geometry rotor configurations can offer substantial improvements in hover performance without adversely affecting forward flight performance. Axial spacing of alternate blades was found to provide the greatest performance benefit, and further improvements were achieved by combining azimuth spacing with axial spacing. The performance benefit appears to be related to the relief of local adverse aerodynamic phenomena produced by vortex interference. The ogee tip design was found to substantially reduce the concentrated core intensity of the tip vortex, and could thus prove beneficial for the relief of blade-vortex interaction problems. However, the ogee tip was found to reduce hover performance at model scale
Prenatal Lead Levels, Plasma Amyloid Ī² Levels, and Gene Expression in Young Adulthood
Background: Animal studies suggest that early-life lead exposure influences gene expression and production of proteins associated with Alzheimerās disease (AD)
Studies on the Occurrence and Elemental Composition of Bacteria in Freshwater Plankton
The occurrence and cation content of bacteria in a eutrophic freshwater lake (Rostherne Mere, Cheshire, UK) were investigated over a one year sampling period in relation to cation changes in the lake surface water and phytoplankton.
Scanning electron microscope examination of trawl-net and filtered samples demonstrated bacterial association with Anabaena, Aphanizomenon and diatoms. Direct counts of associated and unassociated bacteria showed that increases in bacterial population relate to population decline of major algal constituents.
Spectrophotometric determination of selected cation levels in the lake water demonstrated wide fluctuations throughout the sampling period, with elevated levels of transition metals before and at the end of Summer stratification. Zn and Pb also showed increased levels in relation to episodic events.
Mass fractions of spectrophotometrically-determined selected cations (Fe, Cu, Zn and Pb) in phytoplankton also varied considerably during the sampling period, with major increases apparently following peaks in water level.
X-ray microanalysis of whole, unassociated bacterial eel ls demonstrated high levels of soluble and bound cations, including K, Ca, Fe, Cu, Ni, Zn and Pb. Changes in the cation levels of bacteria did not follow a similar pattern to the general phytoplankton - probably due to differences in uptake or adsorption or to cycling of bacterial cells in the water column
Reduced Intellectual Development in Children with Prenatal Lead Exposure
OBJECTIVE: Low-level postnatal lead exposure is associated with poor intellectual development in children, although effects of prenatal exposure are less well studied. We hypothesized that prenatal lead exposure would have a more powerful and lasting impact on child development than postnatal exposure. DESIGN: We used generalized linear mixed models with random intercept and slope to analyze the pattern of lead effect of the cohort from pregnancy through 10 years of age on child IQ from 6 to 10 years. We statistically evaluated doseāresponse nonlinearity. PARTICIPANTS: A cohort of 175 children, 150 of whom had complete data for all included covariates, attended the National Institute of Perinatology in Mexico City from 1987 through 2002. EVALUATIONS/MEASUREMENTS: We used the Wechsler Intelligence Scale for ChildrenāRevised, Spanish version, to measure IQ. Blood lead (BPb) was measured by a reference laboratory of the Centers for Disease Control and Prevention (CDC) quality assurance program for BPb. RESULTS: Geometric mean BPb during pregnancy was 8.0 Ī¼g/dL (range, 1ā33 Ī¼g/dL), from 1 through 5 years was 9.8 Ī¼g/dL (2.8ā36.4 Ī¼g/dL), and from 6 through 10 years was 6.2 Ī¼g/dL (2.2ā18.6 Ī¼g/dL). IQ at 6ā10 years decreased significantly only with increasing natural-log third-trimester BPb (Ī² = ā3.90; 95% confidence interval, ā6.45 to ā1.36), controlling for other BPb and covariates. The doseāresponse BPbāIQ function was log-linear, not linearālinear. CONCLUSIONS: Lead exposure around 28 weeks gestation is a critical period for later child intellectual development, with lasting and possibly permanent effects. There was no evidence of a threshold; the strongest lead effects on IQ occurred within the first few micrograms of BPb. RELEVANCE TO CLINICAL PRACTICE: Current CDC action limits for children applied to pregnant women permit most lead-associated child IQ decreases measured over the studied BPb range
Low-level environmental lead exposure in childhood and adult intellectual function: a follow-up study
<p>Abstract</p> <p>Background</p> <p>Early life lead exposure might be a risk factor for neurocognitive impairment in adulthood.</p> <p>Objectives</p> <p>We sought to assess the relationship between early life environmental lead exposure and intellectual function in adulthood. We also attempted to identify which time period blood-lead concentrations are most predictive of adult outcome.</p> <p>Methods</p> <p>We recruited adults in the Boston area who had participated as newborns and young children in a prospective cohort study that examined the relationship between lead exposure and childhood intellectual function. IQ was measured using the Wechsler Abbreviated Scale of Intelligence (WASI). The association between lead concentrations and IQ scores was examined using linear regression.</p> <p>Results</p> <p>Forty-three adults participated in neuropsychological testing. Childhood blood-lead concentration (mean of the blood-lead concentrations at ages 4 and 10 years) had the strongest relationship with Full-Scale IQ (Ī² = -1.89 Ā± 0.70, p = 0.01). Full-scale IQ was also significantly related to blood-lead concentration at age 6 months (Ī² = -1.66 Ā± 0.75, p = 0.03), 4 years (Ī² = -0.90 Ā± 0.41, p = 0.03) and 10 years (Ī² = -1.95 Ā± 0.80, p = 0.02). Adjusting for maternal IQ altered the significance of the regression coefficient.</p> <p>Conclusions</p> <p>Our study suggests that lead exposure in childhood predicts intellectual functioning in young adulthood. Our results also suggest that school-age lead exposure may represent a period of increased susceptibility. Given the small sample size, however, the potentially confounding effects of maternal IQ cannot be excluded and should be evaluated in a larger study.</p
Improved asteroseismic inversions for red-giant surface rotation rates
Asteroseismic observations of internal stellar rotation have indicated a
substantial lack of angular momentum transport in theoretical models of
subgiant and red-giant stars. Accurate core and surface rotation rate
measurements are therefore needed to constrain internal transport processes
included in the models. We eliminate substantial systematic errors of
asteroseismic surface rotation rates found in previous studies. We propose a
new objective function for the Optimally Localized Averages method of
rotational inversions for red-giant stars, which results in more accurate
envelope rotation rate estimates obtained from the same data. We use synthetic
observations from stellar models across a range of evolutionary stages and
masses to demonstrate the improvement. We find that our new inversion technique
allows us to obtain estimates of the surface rotation rate that are independent
of the core rotation. For a star at the base of the red-giant branch, we reduce
the systematic error from about 20% to a value close to 0, assuming constant
envelope rotation. We also show the equivalence between this method and the
method of linearised rotational splittings. Our new rotational inversion method
substantially reduces the systematic errors of red-giant surface rotation
rates. In combination with independent measures of the surface rotation rate,
this will allow better constraints to be set on the internal rotation profile.
This will be a very important probe to further constrain the internal angular
momentum transport along the lower part of the red-giant branch.Comment: 17 pages, 22 figures, accepted for publication in Astronomy and
Astrophysic
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