5 research outputs found
Spectrophotometric Determination of Methandienone in Tablets Using 1.4-Dihydrazinophthalazine
No full textA simple and sensitive method for the determination of methandienone in tablets using 1.4-dihydrazinophthalazine as the reagent is presented. The yellow coloured dihydralazinhydrazone shows the maximum at 401 nm and molar absorptivity of 1.5x104 1 mol-1cm-1. Beer's law is obeyed up to 16 μ g/ml methandienone. The method applied for the assay of methandienone in dosage form gave precise and reproducible results; recovery was 98.57. and relative standard deviation was 1.57%
HPTLC assay of cephalexin and cefaclor in pharmaceuticals
No full textA simple and reliable HPTLC method for the simultaneous determination of cephalexin and cefaclor is developed and validated. The methanol-ethyl acetate-acetone-water (5:2.5:2.5:1.5 v/v/v/v) solvent system is used for the quantitative evaluation of chromatograms. The chromatographic zones, corresponding to the spots of cephalexin and cefaclor on the silica gel plates, are scanned in the reflectance/absorbance mode at 265 nm. The method is found to be reproducible and convenient for the quantitative analysis of cephalexin and cefaclor in its dosage forms
