Topological solitons in highly anisotropic two dimensional ferromagnets

e study the solitons, stabilized by spin precession in a classical two--dimensional lattice model of Heisenberg ferromagnets with non-small easy--axis anisotropy. The properties of such solitons are treated both analytically using the continuous model including higher then second powers of magnetization gradients, and numerically for a discrete set of the spins on a square lattice. The dependence of the soliton energy $E$ on the number of spin deviations (bound magnons) $N$ is calculated. We have shown that the topological solitons are stable if the number $N$ exceeds some critical value $N_{\rm{cr}}$. For $N < N_{\rm{cr}}$ and the intermediate values of anisotropy constant $K_{\mathrm{eff}} <0.35J$ ($J$ is an exchange constant), the soliton properties are similar to those for continuous model; for example, soliton energy is increasing and the precession frequency $\omega (N)$ is decreasing monotonously with $N$ growth. For high enough anisotropy $K_{\mathrm{eff}} > 0.6 J$ we found some fundamentally new soliton features absent for continuous models incorporating even the higher powers of magnetization gradients. For high anisotropy, the dependence of soliton energy E(N) on the number of bound magnons become non-monotonic, with the minima at some "magic" numbers of bound magnons. Soliton frequency $\omega (N)$ have quite irregular behavior with step-like jumps and negative values of $\omega$ for some regions of $N$. Near these regions, stable static soliton states, stabilized by the lattice effects, exist.Comment: 17 page

Explanation and Elaboration Document for the STROBE-Vet Statement: Strengthening the Reporting of Observational Studies in Epidemiology—Veterinary Extension

The STROBE (Strengthening the Reporting of Observational Studies in Epidemiology) statement was first published in 2007 and again in 2014. The purpose of the original STROBE was to provide guidance for authors, reviewers and editors to improve the comprehensiveness of reporting; however, STROBE has a unique focus on observational studies. Although much of the guidance provided by the original STROBE document is directly applicable, it was deemed useful to map those statements to veterinary concepts, provide veterinary examples and highlight unique aspects of reporting in veterinary observational studies. Here, we present the examples and explanations for the checklist items included in the STROBE-Vet Statement. Thus, this is a companion document to the STROBE-Vet Statement Methods and process document, which describes the checklist and how it was developed

Soliton-Magnon Scattering in Two-Dimensional Isotropic Ferromagnets

It is studied the scattering of magnons by the 2d topological Belavin-Polyakov soliton in isotropic ferromagnet. Analytical solutions of the scattering problem are constructed: (i) exactly for any magnon wave vectors for the partial wave with the azimuthal number m=1 (translational mode), and (ii) in the long- and short-wave limits for the rest modes. The magnon mode frequencies are found for the finite size magnets. An effective equation of the soliton motion is constructed. The magnon density of states, connected with the soliton-magnon interaction, is found in a long-wave approximation.Comment: 4 pages, REVTe

Internal Modes and Magnon Scattering on Topological Solitons in 2d Easy-Axis Ferromagnets

We study the magnon modes in the presence of a topological soliton in a 2d Heisenberg easy-axis ferromagnet. The problem of magnon scattering on the soliton with arbitrary relation between the soliton radius R and the "magnetic length" Delta_0 is investigated for partial modes with different values of the azimuthal quantum numbers m. Truly local modes are shown to be present for all values of m, when the soliton radius is enough large. The eigenfrequencies of such internal modes are calculated analytically on limiting case of a large soliton radius and numerically for arbitrary soliton radius. It is demonstrated that the model of an isotropic magnet, which admits an exact analytical investigation, is not adequate even for the limit of small radius solitons, R<<Delta_0: there exists a local mode with nonzero frequency. We use the data about local modes to derive the effective equation of soliton motion; this equation has the usual Newtonian form in contrast to the case of the easy-plane ferromagnet. The effective mass of the soliton is found.Comment: 33 pages (REVTeX), 12 figures (EPS

Both base excision repair and O-6-methylguanine-DNA methyltransferase protect against methylation-induced colon carcinogenesis

Methylating agents are widely distributed environmental carcinogens. Moreover, they are being used in cancer chemotherapy. The primary target of methylating agents is DNA, and therefore, DNA repair is the first-line barrier in defense against their toxic and carcinogenic effects. Methylating agents induce in the DNA O[superscript 6]-methylguanine (O[superscript 6]MeG) and methylations of the ring nitrogens of purines. The lesions are repaired by O[superscript 6]-methylguanine-DNA methyltransferase (Mgmt) and by enzymes of the base excision repair (BER) pathway, respectively. Whereas O[superscript 6]MeG is well established as a pre-carcinogenic lesion, little is known about the carcinogenic potency of base N-alkylation products such as N3-methyladenine and N3-methylguanine. To determine their role in cancer formation and the role of BER in cancer protection, we checked the response of mice with a targeted gene disruption of Mgmt or N-alkylpurine-DNA glycosylase (Aag) or both Mgmt and Aag, to azoxymethane (AOM)-induced colon carcinogenesis, using non-invasive mini-colonoscopy. We demonstrate that both Mgmt- and Aag-null mice show a higher colon cancer frequency than the wild-type. With a single low dose of AOM (3 mg/kg) Aag-null mice showed an even stronger tumor response than Mgmt-null mice. The data provide evidence that both BER initiated by Aag and O[superscript 6]MeG reversal by Mgmt are required for protection against alkylation-induced colon carcinogenesis. Further, the data indicate that non-repaired N-methylpurines are not only pre-toxic but also pre-carcinogenic DNA lesions.Deutsche Forschungsgemeinschaft (DFG) (FOR 527)Deutsche Forschungsgemeinschaft (DFG) (DFG KA 724/13-3)Deutsche Forschungsgemeinschaft (DFG) (WI 3304/1-1

A global reference database of crowdsourced cropland data collected using the Geo-Wiki platform

A global reference data set on cropland was collected through a crowdsourcing campaign using the Geo-Wiki crowdsourcing tool. The campaign lasted three weeks, with over 80 participants from around the world reviewing almost 36,000 sample units, focussing on cropland identification. For quality assessment purposes, two additional data sets are provided. The first is a control set of 1,793 sample locations validated by students trained in satellite image interpretation. This data set was used to assess the quality of the crowd as the campaign progressed. The second data set contains 60 expert validations for additional evaluation of the quality of the contributions. All data sets are split into two parts: the first part shows all areas classified as cropland and the second part shows cropland average per location and user. After further processing, the data presented here might be suitable to validate and compare medium and high resolution cropland maps generated using remote sensing. These could also be used to train classification algorithms for developing new maps of land cover and cropland extent

Direct and indirect effects of interspecific competition in a highly partitioned guild of reef fishes

Competitive interactions and resource partitioning facilitate species coexistence in complex ecosystems. However, while pairwise interactions between ecologically similar species have been well studied, multi‐species competitive networks have received less attention. When interference competition between two species results in partitioning of resources, this may have indirect consequences for other species distributed along the same resource gradient. Here, we tested whether interference competition between two territorial damselfish influenced the fine‐scale species distributions of five other territorial damselfish in Kimbe Bay, Papua New Guinea. These species partition habitat across three reef zones—the flat, crest, and slope, with distinct patterns of distribution within these zones. We predicted the two species with similar distributions and microhabitat use, Pomacentrus adelus and Pomacentrus bankanensis, would display the greatest level of aggression toward one another. This was tested through an intruder experiment where stimulus fish were introduced into a resident's territory, which confirmed disproportionately high levels of interspecific aggression between these two species. We also predicted that the fine‐scale differences in the distribution of each species were maintained through multi‐species interference competition among neighboring species, with further indirect effects on species that did not directly interact. To test this, we conducted a large‐scale (22 × 10 m) experimental removal of the most abundant species, Po. adelus, and quantified the abundance and distribution of all territorial damselfish species for 6 months to a 25 cm resolution. The main direct competitor, Po. bankanensis, exhibited a marked increase in abundance and expanded its distribution (+1.33 m) to acquire the space previously occupied by Po. adelus. This competitive release triggered indirect effects on the distribution of other neighboring species further back on the reef flat, with Chrysiptera unimaculata moving into the zone formerly occupied by Po. bankanensis. This study indicates that the distinct distribution patterns among the reef crest species are linked to levels of interspecific agonistic behavior. We argue that the competitive release following the removal of a superior competitor resulted in both direct and indirect effects, with the immediate neighbor shifting into the newly available space, followed by successive shifts in species responding to the change in the distributions of their immediate neighbors

Energy dependence of the differences between the quark and gluon jet fragmentation

Three jet events arising from decays of the Z boson, collected by the DELPHI detector, were used to measure differences in quark and gluon fragmentation. Gluon jets were anti-tagged by identifying b quark jets. Unbiased quark jets came from events with two jets plus one photon. Quark and gluon jet properties in different energy ranges were compared for the first time within the same detector. Quark and gluon jets of nearly the same energy in symmetric three jet event topologies were also compared. Using three independent methods, the average value of the ratio of the mean charged multiplicities of gluon and quark jets is $$=1.241\pm 0.015\ (stat.) \pm 0.025\ (syst.).$$ Gluon jets are broader and produce fragments with a softer energy spectrum than quark jets of equivalent energy. The string effect has been observed in fully symmetric three jet events. The measured ratio R_{\gamma} of the charged particle flow in the q\overline{q} inter-jet region of the q\bar{q}g and q\bar{q}\gamma samples agrees with the perturbative QCD expectation. The dependence of the mean charged multiplicity on the hadronic center-of-mass energy was analysed in photon plus n-jet events. The value for \alpha_s(M_Z) determined from these data using a QCD prediction with corrections at leading and next-to-leading order is \[ \alpha_s(M_Z)=0.116 \pm 0.003\ (stat.) \pm 0.009\ (syst.). \

Natural humoral immune response to ribosomal P0 protein in colorectal cancer patients

Tumor associated antigens are useful in colorectal cancer (CRC) management. The ribosomal P proteins (P0, P1, P2) play an important role in protein synthesis and tumor formation. The immunogenicity of the ribosomal P0 protein in head and neck, in breast and prostate cancer patients and the overexpression of the carboxyl-terminal P0 epitope (C-22 P0) in some tumors were reported