Time Delay Induced Death in Coupled Limit Cycle Oscillators

We investigate the dynamical behaviour of two limit cycle oscillators that interact with each other via time delayed coupling and find that time delay can lead to amplitude death of the oscillators even if they have the same frequency. We demonstrate that this novel regime of amplitude "death" also exists for large collections of coupled identical oscillators and provide quantitative measures of this death region in the parameter space of coupling strength and time delay. Its implication for certain biological and physical applications is also pointed out.Comment: 4 aps formatted revtex pages; 3 figures; to be published in Phys. Rev. Let

Photometric Determination of Fluoride Using Various Metal Oximates

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Simulation of electron transport in quantum well devices

Double barrier resonant tunneling diodes (DBRTD) have received much attention as possible terahertz devices. Despite impressive experimental results, the specifics of the device physics (i.e., how the electrons propagate through the structure) are only qualitatively understood. Therefore, better transport models are warranted if this technology is to mature. In this paper, the Lattice Wigner function is used to explain the important transport issues associated with DBRTD device behavior

Experimental Evidence of Time Delay Induced Death in Coupled Limit Cycle Oscillators

Experimental observations of time delay induced amplitude death in a pair of coupled nonlinear electronic circuits that are individually capable of exhibiting limit cycle oscillations are described. In particular, the existence of multiply connected death islands in the parameter space of the coupling strength and the time delay parameter for coupled identical oscillators is established. The existence of such regions was predicted earlier on theoretical grounds in [Phys. Rev. Lett. 80, 5109 (1998); Physica 129D, 15 (1999)]. The experiments also reveal the occurrence of multiple frequency states, frequency suppression of oscillations with increased time delay and the onset of both in-phase and anti-phase collective oscillations.Comment: 4 aps formatted RevTeX pages; 6 figures; to appear in Phys. Rev. Let

Improving B-cell depletion in systemic lupus erythematosus and rheumatoid arthritis

INTRODUCTION: Rituximab-based B-cell depletion (BCD) therapy is effective in refractory rheumatoid arthritis (RA) and although used to treat patients with refractory systemic lupus erythematosus (SLE) in routine clinical practice, rituximab failed to meet the primary endpoints in two large randomised controlled trials (RCTs) of non-renal (EXPLORER) and renal (LUNAR) SLE. Areas covered: We review how BCD could be improved to achieve better clinical responses in RA and SLE. Insights into the variability in clinical response to BCD in RA and SLE may help develop new therapeutic strategies. To this end, a literature search was performed using the following terms: rheumatoid arthritis, systemic erythematosus lupus, rituximab and B-cell depletion. Expert commentary: Poor trial design may have, at least partly, contributed to the apparent lack of response to BCD in the two RCTs of patients with SLE. Enhanced B-cell depletion and/or sequential therapy with belimumab may improve clinical response at least in some patients with SLE

Meissner screening mass in two-flavor quark matter at nonzero temperature

We calculate the Meissner screening mass of gluons 4--7 in two-flavor quark matter at nonzero temperature. To this end, we study the effective potential of the 2SC/g2SC phases including a vector condensate $$and calculate the Meissner mass from the potential curvature with respect to$$. We find that the Meissner mass becomes real at the critical temperature which is about the half of the chemical potential mismatch. The phase diagram of the neutral two-flavor color superconductor is presented in the plane of temperature and coupling strength. We indicate the unstable region for gluons 4--7 on the phase diagram.Comment: 4 pages, 3 figures, minor revisions to text, version to appear in PR