Ethanol Affects Differentiation‐Related Pathways and Suppresses Wnt Signaling Protein Expression in Human Neural Stem Cells

Peer Reviewedhttp://deepblue.lib.umich.edu/bitstream/2027.42/91167/1/j.1530-0277.2011.01682.x.pd

Effect of feeding maize fiber in wet, dry and silage form with cotton cake supplementation on intake, nutrient utilization and performance in Nellore Brown sheep

Maize fiber was evaluated in wet, dry and silage form with 200 g cotton cake supplementation in growing Nellore Brown ram lambs (24.8±0.96) using six sheep per treatment in a growth-cummetabolism trial of 90 days with collection of feed, leftover, feces and urine samples during the last ten days. Average daily gain (g), nutrient digestibility (OM, CP, NDF, ADF) tended to be higher (P = 0.07 to 0.09) and intake of OM, DOM, CP (gld) and ME (MJ!d) and nitrogen retention were significantly (P = 0. 0002 to 0. 002) higher in lambs when fed maize fiber in silage rather than in wet and dry form. Depending on input such as labor required ensilaging or drying of maize fiber seems an economically more beneficial and from a food security point of view a safer way than feeding wet maize fiber

One-Pot Palladium-Catalyzed Ligand- and Metal-Oxidant-Free Aerobic Oxidative Isocyanide Insertion Leading to 2-Amino-substituted-4(3H)-quinazolinones

An efficient, ligand- and metal-oxidant-free, one-pot, cascade aerobic oxidative, palladium-catalyzed, multicomponent reaction has been developed through isocyanide insertion of less active secondary amide and aromatic amine, which leads to 2-amino-substituted-4(3H)-quinazolinones. This approach proves to be one of the simplest methods for the synthesis of this class of valuable bioactive heterocyclic scaffolds

Evaluation of Surface Water Quality Using Water Quality Index (WQI) and GIS Tool Of Anantapur Location

The objective of this study is to estimate the quality of surface water in a semi-arid area of India, specifically in the pond located in Old Town, BKS Katta Road, Anantapur. The water quality index (WQI) is used to calculate the quality of the water samples taken from the pond, and a map of the water quality was created using geographic information system (GIS). The samples were analyzed for various factors including Electrical Conductivity (EC), Odour, Taste, pH, Temperature, Calcium (Ca2+), Magnesium, Total dissolved solids (TDS), Bicarbonate (HCO-3), Chloride (Cl-), Biological Oxygen Demand (BOD), Chemical Oxygen Demand (COD), Dissolved Oxygen (DO), Nitrate (NO-3) and Iron (Fe-). Based on these analyses, spatial distribution maps were also prepared using GIS. The WQI values swayed from 61.875 to 74, ensuring that the pond water samples were of the highest quality and safe for direct consumption

High Energy Neutrino Signals of Four Neutrino Mixing

We evaluate the upward shower and muon event rates for two characteristic four neutrino mixing models for extragalactic neutrinos, as well as for the atmospheric neutrinos, with energy thresholds of 1 TeV, 10 TeV and 100 TeV. We show that by comparing the shower to muon event rates, one can distinguish between oscillation and no-oscillation models. By measuring shower and muon event rates for energy thresholds of 10 TeV and 100 TeV, and by considering their ratio, it is possible to use extragalactic neutrino sources to determine the type of four-flavor mixing pattern. We find that one to ten years of data taking with kilometer-size detector has a very good chance of providing valuable information about the physics beyond the Standard Model.Comment: version accepted for publication in Phys. Rev.

A study of efficacy of pap smear in a rural medical college and hospital

Background: To screen women for cervical cancer using pap smear technique in rural medical college and hospital. To compare the results with other studies early diagnosis of precancerous lesion of carcinoma of cervix To bring awareness among public. Cervical screening using age, symptoms, per speculum examination as parameters and to compare results with other studies. Methods: In this retrospective study, reports of pap smear test, which was done to women attending obstetrics and gynaecology clinic in the period January 2024 to August 2024, was obtained from department of pathology of Adichunchanagiri institute of medical sciences, B. G. Nagara. During this period total of 620 smears were assessed. Results: 38.01% had white discharge per vagina, 67.76% had other symptoms like irregular menstrual cycle, abdominal pain, intermenstrual bleeding, secondary amenorrhea etc, 9.2% had no symptoms. Total of 31 (5.12%) smears were found abnormal. Atypical squamous cells of undetermined significance (ASC-US) in 2.4%, Atypical squamous cells cannot exclude high grade squamous intraepithelial lesion (ASC-H) in 1.32%, low grade squamous intraepithelial lesion (LSIL) in 0.66% and high-grade intraepithelial lesion (HSIL) in 0.33%. Conclusions: Pap smear is a simple, cost effective, easily accessible screening test which has to be utilised for early detection and treatment of precancerous lesions of carcinoma cervix. Awareness among rural people regarding benefits of screening test has to be made and encourage them to participat

ANTIPROLIFERATIVE EFFECTS OF PSIDIUM GUAJAVA LEAF EXTRACT ON ORAL SQUAMOUS CARCINOMA CELLS

Objective: Cancer is the major cause of mortality affecting population irrespective of age. Oral cancer is one among the various cancers affecting major population in India. To overcome toxicity of chemotherapy and disfiguration by surgical procedures, researchers are targeting phytochemicals for their anticancer properties. This study evaluates the antiproliferative effects of Psidium guajava leaf extract against OSC cells. Methods: KB cells were purchased from NCCS, Pune. Extract from leaves of P. guajava was prepared with ethanol and evaluated with high-performance thin-layer chromatography (HPTLC). Antiproliferative effects of the extract were assessed with 3-(4,5-dimethyl-2-thiazolyl)-2,5-diphenyl--tetrazolium bromide (MTT) assay and flow cytometry. Results: HPTLC revealed the presence of quercetin in the extract. MTT assay showed decreasing pattern in cell viability with the increasing dose of extract. Flow cytometry revealed the seizing of cycle by the extract. Conclusion: The study results conclude the presence of antiproliferative properties in the leaf extract of P. guajava

Radix formation between median and musculocutaneous nerves: embryological, morphological and clinical correlation

In ours study we report radix formation between median nerve and musculocutaneous nerves. The study was conducted in the Department of Anatomy, Kamineni Institute of Medical Sciences, Narketpally, Nalgonda Dt., Andhra Pradesh, India. During routine cadaveric dissections in the upper limbs, we observed an anastomosis (radix) between median and musculocutaneous nerves in the arm. Variations in the origin, course, branching pattern, communications was observed. These variations have clinical significance in brachial plexus block and surgical procedures