14 research outputs found

    Interferensi Bahasa Bali dan Bahasa Asing dalam Cerita Lisan Bahasa Indonesia Kelas VII Siswa SMP Negeri 10 Denpasar

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    This study uses the technique of observation, record, record. The results of this study showed 18 students did not slip Balinese language and foreign language, whereas 32 respondents are interference ranges one and two interference in a discourse. In Bali interference there are kind interferences, those are phonology interference, morphology, syntax, and semantics, while the interference of foreign languages ​​are syntactic and semantic. Balinese language interference into the Indonesian language showing that interference is not due to deliberate by students in order to facilitate the delivery of his thoughts, but it is because control systems first language (Balinese) they are higher than their ability recalled the Indonesian language. It was concluded that the interference is part of sociolinguistics that occur due to the use of two or more languages ​​in a multilingual speech community

    Renal Thrombotic Microangiopathy in Mice with Combined Deletion of Endocytic Recycling Regulators EHD3 and EHD4

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    Eps15 Homology Domain-containing 3 (EHD3), a member of the EHD protein family that regulates endocytic recycling, is the first protein reported to be specifically expressed in the glomerular endothelium in the kidney; therefore we generated Ehd3–/– mice and assessed renal development and pathology. Ehd3–/– animals showed no overt defects, and exhibited no proteinuria or glomerular pathology. However, as the expression of EHD4, a related family member, was elevated in the glomerular endothelium of Ehd3–/– mice and suggested functional compensation, we generated and analyzed Ehd3–/–; Ehd4–/– mice. These mice were smaller, possessed smaller and paler kidneys, were proteinuric and died between 3–24 weeks of age. Detailed analyses of Ehd3–/–; Ehd4–/– kidneys demonstrated thrombotic microangiopathy (TMA)-like glomerular lesions including thickening and duplication of glomerular basement membrane, endothelial swelling and loss of fenestrations. Other changes included segmental podocyte foot process effacement, mesangial interposition, and abnormal podocytic and mesangial marker expression. The glomerular lesions observed were strikingly similar to those seen in human pre-eclampsia and mouse models of reduced VEGF expression. As altered glomerular endothelial VEGFR2 expression and localization and increased apoptosis was observed in the absence of EHD3 and EHD4, we propose that EHD-mediated endocytic traffic of key surface receptors such as VEGFR2 is essential for physiological control of glomerular function. Furthermore, Ehd3–/–; Ehd4–/– mice provide a unique model to elucidate mechanisms of glomerular endothelial injury which is observed in a wide variety of human renal and extra-renal diseases

    Lesion sterilization and tissue repair therapy using GAM antibiotic paste: A series of cases

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    Despite the efforts to prevent dental caries among children, premature loss of primary teeth due to pulp and periapical diseases is a common problem. The effect of this premature loss on the development of dentition is a matter of great interest. Importantly, the primary teeth are considered as natural space maintainers and therefore should be retained until their natural exfoliation. Based on these issues and concerns, the concept of “Lesion sterilization and tissue repair (LSTR)” therapy proposed by the Cariology Research Unit of the Niigata University School of Dentistry, would be preferable to current endodontic treatments
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