On the Determinants of Distribution Dynamics

n this paper we propose a novel approach to identify the impact of growth determinants on the distribution dynamics of productivit y. Our approach integrates counterfactual analysis with the estima tion of stochastic kernels. The counterfactuals are constructed from a semi-parametric growth regression, in which the cross-section heterogeneity in the growth determinants is removed. The methodology also allows us to test for potential distributional effects in the residuals. We illustrate the usefulness of the proposed methodology by an application to a cross-section of countries, which highlights the significant impact on inequality and polarization in the world productivity distribution of growth determinants from an augmented Solow model

On the Determinants of Distribution Dynamics

n this paper we propose a novel approach to identify the impact of growth determinants on the distribution dynamics of productivit y. Our approach integrates counterfactual analysis with the estima tion of stochastic kernels. The counterfactuals are constructed from a semi-parametric growth regression, in which the cross-section heterogeneity in the growth determinants is removed. The methodology also allows us to test for potential distributional effects in the residuals. We illustrate the usefulness of the proposed methodology by an application to a cross-section of countries, which highlights the significant impact on inequality and polarization in the world productivity distribution of growth determinants from an augmented Solow model

Productivity Dynamics across European Regions: the Impact of Structural and Cohesion Funds

This paper analyzes the impact of the European Union regional policy of the three programming periods 1975-1988, 1989-1993 and 1994-1999 on the dynamics of productivity of European regions. On average, funding had a positive, but concave, e\ufb00ect on productivity growth. In particular, a share of funds on GVA of 10% GVA is estimated to raise the regional growth rate of about 0.9% per year. However, by separately considering the three programming periods and the composition of the funds according to the objectives de\ufb01ned by the EU, we \ufb01nd that: i) only the funds allocated in the second and third programming periods, when they remarkably increased, had a signi\ufb01cant impact; and ii) only Objective 1 and Cohesion funds played a signi\ufb01cantly positive impact, while funds devoted to Objectives 2, 3, 4 and 5 had a negative or non signi\ufb01cant impact. The results are robust to potential endogeneity of funds and spatial dependence

Counterfactual Distribution Dynamics across European Regions

This paper proposes a methodology which combines elements of parametric regression analysis with the nonparametric distribution dynamics approach in order to analyse the role of some variables in the convergence of productivity across European regions over the period 1980-2002. We find that the initial productivity crucially accounts in the convergence process across European regions. Differently, employment growth seems not to play a role, while the Structural and Cohesion Funds seem to play a positive role, even though such effect seems to be very low and statistically significant only at the low bound of the range of initial productivity. The structural change of regional economies plays a positive role, but such effect is statistically significant only for the least productive regions. The output composition of a region in 1980 affects the convergence process of productivity growth in several ways. In particular, the share of non market services on output acts like a source of convergence from 1980 to 2002 but in the long-run it plays a negligible role. Finally, the share of finance acts like a force of divergence across European regions, especially for the least productive regions

The IkB kinase inhibitor nuclear factor-kB essential modulator–binding domain peptide for inhibition of balloon injury-induced neointimal formation

Objective—The activation of nuclear factor-kB (NF-kB) is a crucial step in the arterial wall’s response to injury. The identification and characterization of the NF-kB essential modulator– binding domain (NBD) peptide, which can block the activation of the IkB kinase complex, have provided an opportunity to selectively abrogate the inflammation-induced activation of NF-kB. The aim of the present study was to evaluate the effect of the NBD peptide on neointimal formation.<br></br> Methods and Results—In the rat carotid artery balloon angioplasty model, local treatment with the NBD peptide (300 microg/site) significantly reduced the number of proliferating cells at day 7 (by 40%; P<0.01) and reduced injury-induced neointimal formation (by 50%; P<0.001) at day 14. These effects were associated with a significant reduction of NF-kB activation and monocyte chemotactic protein-1 expression in the carotid arteries of rats treated with the peptide. In addition, the NBD peptide (0.01 to 1 micromol/L) reduced rat smooth muscle cell proliferation, migration, and invasion in vitro. Similar results were observed in apolipoprotein E-/-, mice in which the NBD peptide (150 microg/site) reduced wire-induced neointimal formation at day 28 (by 47%; P<0.01).<br></br> Conclusion—The NBD peptide reduces neointimal formation and smooth muscle cell proliferation/migration, both effects associated with the inhibition of NF-kB activation

'White knuckle care work' : violence, gender and new public management in the voluntary sector

Drawing on comparative data from Canada and Scotland, this article explores reasons why violence is tolerated in non-profit care settings. This article will provide insights into how workers' orientations to work, the desire to care and the intrinsic rewards from working in a non-profit context interact with the organization of work and managerially constructed workplace norms and cultures (Burawoy, 1979) to offset the tensions in an environment characterized by scarce resources and poor working conditions. This article will also outline how the same environment of scarce resources causes strains in management's efforts to establish such cultures. Working with highly excluded service users with problems that do not respond to easy interventions, workers find themselves working at the edge of their endurance, hanging on by their fingernails, and beginning to participate in various forms of resistance; suggesting that even among the most highly committed, 'white knuckle care' may be unsustainable

Collection Of Freshwater And Coastal Fishes From Sulawesi Tenggara, Indonesia [Koleksi Ikan-ikan Air Tawar dan Pantai di Sulawesi Tenggara]

We report 69 fish species in 34 teleost families nearly all collected during a preliminary survey of the Sungai Pohara and coastal localities in Sulawesi Tenggara, including Muna Island, in June 2010. Of these species, nine are introduced or exotic and another is questionably native. The family Gobiidae is the most diverse taxon, represented by 14 native species. Atherinomorph fishes of the family Adrianichthyidae are represented in the province by four endemic species and two others that are widespread, all in the genus Oryzias. This fish fauna contrasts sharply with the riverine ichthyo-fauna of the adjacent Sulawesi Tenggara islands of Buton and Kabaena in which there are reportedly no ricefishes and few endemics. New species are being described by the field team and collaborators. Our ultimate goal is to discover, describe, highlight, understand and encourage the conservation of the native freshwater and coastal fish biota of Sulawesi

Wodzicki Residue for Operators on Manifolds with Cylindrical Ends

We define the Wodzicki Residue TR(A) for A in a space of operators with double order (m_1,m_2). Such operators are globally defined initially on R^n and then, more generally, on a class of non-compact manifolds, namely, the manifolds with cylindrical ends. The definition is based on the analysis of the associate zeta function. Using this approach, under suitable ellipticity assumptions, we also compute a two terms leading part of the Weyl formula for a positive selfadjoint operator belonging the mentioned class in the case m_1=m_2.Comment: 24 pages, picture changed, added references, corrected typo

Growth factor restriction impedes progression of wound healing following cataract surgery: identification of VEGF as a putative therapeutic target

Secondary visual loss occurs in millions of patients due to a wound-healing response, known as posterior capsule opacification (PCO), following cataract surgery. An intraocular lens (IOL) is implanted into residual lens tissue, known as the capsular bag, following cataract removal. Standard IOLs allow the anterior and posterior capsules to become physically connected. This places pressure on the IOL and improves contact with the underlying posterior capsule. New open bag IOL designs separate the anterior capsule and posterior capsules and further reduce PCO incidence. It is hypothesised that this results from reduced cytokine availability due to greater irrigation of the bag. We therefore explored the role of growth factor restriction on PCO using human lens cell and tissue culture models. We demonstrate that cytokine dilution, by increasing medium volume, significantly reduced cell coverage in both closed and open capsular bag models. This coincided with reduced cell density and myofibroblast formation. A screen of 27 cytokines identified nine candidates whose expression profile correlated with growth. In particular, VEGF was found to regulate cell survival, growth and myofibroblast formation. VEGF provides a therapeutic target to further manage PCO development and will yield best results when used in conjunction with open bag IOL designs