30 research outputs found

    Protective effect of a fish egg homogenate marine compound on arterial ultrastructure in spontaneous hypertensive rats

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    We assessed the effect of a sturgeon eggs-based nutraceutical (LD-1227) versus eicosapentaenoic acid (EPA)/docosahexaenoic acid (DHA) on the ultrastructure of spontaneously hypertensive rat (SHR) aortas. Sixty SHR were randomly divided into three groups that were fed (1) rat chow, (2) rat chow plus 10 mg of EPA/DHA, or (3) rat chow plus 10 mg of LD-1227, for 18 weeks. Afterward, aortas of these rats were used for blind measurements of the thickened intima area and examination by electron microscopy. Control SHR showed an expanded subendothelial space and leukocyte infiltration of the intima that were reduced in LD-1227-fed rats (p<0.05) and less in EPA/DHA group. Transmission electron microscopy showed endothelial alteration with severe subcellular injury and, unlike the EPA/DHA-group, LD-1227-treated rats displayed a significant reduction in endothelial alteration with severe subcellular injury (p<0.05). These data suggest that LD-1227 has stronger arterial protective properties and deserves further investigation in view of a preventive medicine strategy

    On the Move to Meaningful Internet Systems: OTM 2011 Part II

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    The two-volume set LNCS 7044 and 7045 constitutes the refereed proceedings of three confederated international conferences: Cooperative Information Systems (CoopIS 2011), Distributed Objects and Applications - Secure Virtual Infrastructures (DOA-SVI 2011), and Ontologies, DataBases and Applications of SEmantics (ODBASE 2011) held as part of OTM 2011 in October 2011 in Hersonissos on the island of Crete, Greece. The 55 revised full papers presented were carefully reviewed and selected from a total of 141 submissions. The 28 papers included in the second volume constitute the proceedings of DOA-SVI 2011 with 15 full papers organized in topical sections on performance measurement and optimization, instrumentation, monitoring, and provisioning, quality of service, security and privacy, and models and methods, and ODBASE 2011 with 9 full papers organized in topical sections on acquisition of semantic information, use of semantic information, and reuse of semantic information and 4 short papers

    On the Move to Meaningful Internet Systems: OTM 2011 Part I

    No full text
    The two-volume set LNCS 7044 and 7045 constitutes the refereed proceedings of three confederated international conferences: Cooperative Information Systems (CoopIS 2011), Distributed Objects and Applications - Secure Virtual Infrastructures (DOA-SVI 2011), and Ontologies, DataBases and Applications of SEmantics (ODBASE 2011) held as part of OTM 2011 in October 2011 in Hersonissos on the island of Crete, Greece. The 55 revised full papers presented were carefully reviewed and selected from a total of 141 submissions. The 27 papers included in the first volume constitute the proceedings of CoopIS 2011 and are organized in topical sections on business process repositories, business process compliance and risk management, service orchestration and workflows, intelligent information systems and distributed agent systems, emerging trends in business process support, techniques for building cooperative information systems, security and privacy in collaborative applications, and data and information management
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