10,581 research outputs found
The microeconomic determinants of emigration and return migration of the best and brightest: evidence from the Pacific
A unique survey which tracks worldwide the best and brightest academic performers from three Pacific countries is used to assess the extent of emigration and return migration among the very highly skilled, and to analyze, at the microeconomic level, the determinants of these migration choices. Although we estimate that the income gains from migration are very large, not everyone migrates and many return. Within this group of highly skilled individuals the emigration decision is found to be most strongly associated with preference variables such as risk aversion, patience, and choice of subjects in secondary school, and not strongly linked to either liquidity constraints or to the gain in income to be had from migrating. Likewise, the decision to return is strongly linked to family and lifestyle reasons,
rather than to the income opportunities in different countries. Overall the data show a relatively limited role for income maximization in distinguishing migration propensities among the very highly skilled, and a need to pay more attention to other components of the utility maximization decision
A land of milk and honey with streets paved with gold: do emigrants have over-optimistic expectations about incomes abroad?
Millions of people emigrate every year in search of better economic and social
opportunities. Anecdotal evidence suggests that emigrants may have over-optimistic
expectations about the incomes they can earn abroad, resulting in excessive
migration pressure, and in disappointment amongst those who do migrate. Yet there
is almost no statistical evidence on how accurately these emigrants predict the
incomes that they will earn working abroad. In this paper we combine a natural
emigration experiment with unique survey data on would-be emigrants’ probabilistic
expectations about employment and incomes in the migration destination. Our
procedure enables us to obtain moments and quantiles of the subjective distribution
of expected earnings in the destination country. We find a significant underestimation
of both unconditional and conditional labor earnings at all points in the
distribution. This under-estimation appears driven in part by potential migrants
placing too much weight on the negative employment experiences of some
migrants, and by inaccurate information flows from extended family, who may be
trying to moderate remittance demands by understating incomes
Studies of auroral X-ray imaging from high altitude spacecraft
Results of a study of techniques for imaging the aurora from a high altitude satellite at X-ray wavelengths are summarized. The X-ray observations allow the straightforward derivation of the primary auroral X-ray spectrum and can be made at all local times, day and night. Five candidate imaging systems are identified: X-ray telescope, multiple pinhole camera, coded aperture, rastered collimator, and imaging collimator. Examples of each are specified, subject to common weight and size limits which allow them to be intercompared. The imaging ability of each system is tested using a wide variety of sample spectra which are based on previous satellite observations. The study shows that the pinhole camera and coded aperture are both good auroral imaging systems. The two collimated detectors are significantly less sensitive. The X-ray telescope provides better image quality than the other systems in almost all cases, but a limitation to energies below about 4 keV prevents this system from providing the spectra data essential to deriving electron spectra, energy input to the atmosphere, and atmospheric densities and conductivities. The orbit selection requires a tradeoff between spatial resolution and duty cycle
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Developing theory-informed interventions to implement evidence into practice: a systematic approach using the Theoretical Domains Framework
Background: There is little systematic operational guidance about how best to develop complex interventions to reduce the gap between practice and evidence. This article is one in a series of articles documenting the development and use of the Theoretical Domains Framework (TDF) to advance the science of implementation research.
Methods: The intervention was developed considering three main components: theory, evidence, and practical issues. We used a four-step approach, consisting of guiding questions, to direct the choice of the most appropriate components of an implementation intervention: Who needs to do what, differently? Using a theoretical framework, which barriers and enablers need to be addressed? Which intervention components (behaviour change techniques and mode(s) of delivery) could overcome the modifiable barriers and enhance the enablers? And how can behaviour change be measured and understood?
Results: A complex implementation intervention was designed that aimed to improve acute low back pain management in primary care. We used the TDF to identify the barriers and enablers to the uptake of evidence into practice and to guide the choice of intervention components. These components were then combined into a cohesive intervention. The intervention was delivered via two facilitated interactive small group workshops. We also produced a DVD to distribute to all participants in the intervention group. We chose outcome measures in order to assess the mediating mechanisms of behaviour change.
Conclusions: We have illustrated a four-step systematic method for developing an intervention designed to change clinical practice based on a theoretical framework. The method of development provides a systematic framework that could be used by others developing complex implementation interventions. While this framework should be iteratively adjusted and refined to suit other contexts and settings, we believe that the four-step process should be maintained as the primary framework to guide researchers through a comprehensive intervention development process
Detergent Extraction of a Presumptive Gating Component from the Voltage-Dependent Sodium Channel
A physiologically characterized radiolabeled neurotoxin complex obtained from venom of the scorpion Leiurus quinquestriatus has been used to identify detergent-solubilized presumptive sodium channel components in sucrose gradients. This toxin-binding component is found in extracts prepared from three sources of excitable membrane but appears to be absent from similar extracts prepared from nonexcitable membrane or from Torpedo californica membrane. Procedures that destroy the physiological activity of the Leiurus neurotoxin lead to a corresponding loss of toxin binding to the putative sodium channel component. The major component recognized by the Leiurus toxin sediments at 6.5 S. Scatchard analysis of quantitative binding experiments carried out in sucrose gradients shows approximately linear plots and indicates that the toxin recognizes a relatively small number of sites with a dissociation constant near 10 nM. Once formed, the channel element--toxin complex is quite stable. Experiments show diphasic dissociation kinetics with half-times near 70 hr and greater than 200 hr
Effect of rurality on screening for breast cancer: a systematic review and meta-analysis comparing mammography
Introduction: The lower breast cancer survival rate observed among rural women may be related to differences in screening access and utilization. We evaluated existing evidence for rural and urban differences in mammography service use in adult women
Comment on "Plasma ionization by annularly bounded helicon waves" [Phys . Plasmas 13, 063501 (2006)]
The neoclassical calculation of the helicon wave theory contains a
fundamental flaw. Use is made of a proportional relationship between the
magnetic field and its curl to derive the Helmholtz equation describing helicon
wave propagation; however, by the fundamental theorem of Stokes, the curl of
the magnetic field must be perpendicular to that portion of the field
contributing to the local curl. Reexamination of the equations of motion
indicates that only electromagnetic waves propagate through a stationary region
of constant pressure in a fully ionized, neutral medium.Comment: 7 pages, 1 figure, to be published in Phys. Plasmas,
http://link.aip.org/link/?PHPAEN/16/054701/
A Method to Determine the In-Air Spatial Spread of Clinical Electron Beams
We propose and analyze in detail a method to measure the in-air spatial
spread parameter of clinical electron beams. Measurements are performed at the
center of the beam and below the adjustable collimators sited in asymmetrical
configuration in order to avoid the distortions due to the presence of the
applicator. The main advantage of our procedure lies in the fact that the dose
profiles are fitted by means of a function which includes, additionally to the
Gaussian step usually considered, a background which takes care of the dose
produced by different mechanisms that the Gaussian model does not account for.
As a result, the spatial spread is obtained directly from the fitting procedure
and the accuracy permits a good determination of the angular spread. The way
the analysis is done is alternative to that followed by the usual methods based
on the evaluation of the penumbra width. Besides, the spatial spread found
shows the quadratic-cubic dependence with the distance to the source predicted
by the Fermi-Eyges theory. However, the corresponding values obtained for the
scattering power are differing from those quoted by ICRU nr. 35 by a factor ~2
or larger, what requires of a more detailed investigation.Comment: 11 pages, 5 Postscript figures, to be published in Medical Physic
Discrete Lie Advection of Differential Forms
In this paper, we present a numerical technique for performing Lie advection
of arbitrary differential forms. Leveraging advances in high-resolution finite
volume methods for scalar hyperbolic conservation laws, we first discretize the
interior product (also called contraction) through integrals over Eulerian
approximations of extrusions. This, along with Cartan's homotopy formula and a
discrete exterior derivative, can then be used to derive a discrete Lie
derivative. The usefulness of this operator is demonstrated through the
numerical advection of scalar fields and 1-forms on regular grids.Comment: Accepted version; to be published in J. FoC
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