166 research outputs found

    Applications of the cavity ring-down technique to a large area rf-plasma reactor

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    Dans une Inde presque encore aux trois quarts rurale, culture des villes et culture des champs peuvent sembler antagonistes: pourtant, le regard contempteur des citadins, l'agressivité en retour d'un "villagisme" dont les idéaux gandhiens ont été largement pervertis et qui s'appuie sur la dénonciation d'un contestable "parti-pris urbain", aussi bien que l'attachement des ruraux à leur village, ne doivent pas faire oublier la complémentarité des deux économies urbaine et rurale: une réalité économique dont rendent compte même les manuels scolaires du primaire. En fait, les paysans qui migrent en ville parviennent à passer d'une culture à l'autre sans trop de difficultés : sans doute parce que la ville ne représente guère pour eux un milieu beaucoup plus étranger que ne l'est un village différent du leur, ou une caste autre. (Résumé d'auteur

    Cerebropulmonary dysgenetic syndrome

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    Author Posting. © The Author(s), 2008. This is the author's version of the work. It is posted here by permission of Elsevier B.V. for personal use, not for redistribution. The definitive version was published in Experimental and Molecular Pathology 85 (2008): 112-116, doi:10.1016/j.yexmp.2008.04.006.Ventilatory treatment of neonatal respiratory distress often results in bronchopulmonary dysplasia from congenital surfactant deficiency due to mutants of transporter protein ABCA3. Association of this condition with other severe disorders in premature newborns has not heretofore been reported. A neonatal autopsy included an in vivo whole blood sample for genetic tcsting. Autopsy revealed severe interstitial pulmonary fibrosis at age 8 days with heterozygotic mutation p.E292V of ABCA3 and severe dystrophic retardation of cerebral cortcx and cerebellum. Subsequently, 1300 archival neonatal autopsies, 1983-2006, were reviewed for comparable concurrent findings and bronchopulmonary dysplasia or retarded cerebral dystrophy lacking the other principal feature of this syndrome. Archival review revealed four similar cases and eight less so, without gene analysis. Further review for bronchopulmonary dysplasia revealed 59 cases, 1983-2006. Several other examples of similar retarded migration of germinal matrix and underdevelopment of cortical mantle, without pulmonary lesions of this type, were identified. The determination of an ABCA3 mutation in one case of severe pulmonary fibrosis with significant dystrophy of the brain and the identification of four highly similar archival cases and eight others with partial pathological findings supports the designation of an independent disorder, here referred to as the cerebroprrlmonary dysgenetic syndrome
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