An Efficient Method for Number Plate Detection and Extraction Using White Pixel Detection (WPD) Method

Intelligent transport systems play an important role in supporting smart cities because of their promising applications in various areas, such as electronic toll collection, highway surveillance, urban logistics and traffic management. One of the key components of intelligent transport systems is vehicle license plate recognition, which enables the identification of each vehicle by recognizing the characters on its license plate through various image processing and computer vision techniques. Vehicle license plate recognition typically consists of smoothing image using median filter, White pixel detection (WPD), and number plate extraction. In this work an efficient White pixel detection method has been describing a license plates in various luminance conditions. Mostly we will focus on vehicle number plate detection along with the white pixel detection method we will use median filters and Line density filters to increase the detection accuracy for number plate. Subjective and objective quality assessment parameters will give us robustness of proposed work compared to state of License Plate Detection(LPD) techniques

Case series of Foley’s induction in patients with previous caesarean

Background: The objective of this study was to study the efficacy of intracervical Foley’s catheter induction in women with previous history of caesarean section and to evaluate the maternal and fetal outcome of these pregnancies.Methods: It is a prospective analysis of 30 patients whose labour was induced by intracervical Foley’s bulb for VBAC delivery. This study was conducted in KIMS, Hubli. Age, parity, indication of previous caesarean, inter-pregnancy interval and outcome of index pregnancy were studied in detail and analysed.Results: 30 women with previous history of caesarean were included into the study. Various indications of induction during index pregnancies were- post-datism, IUGR, intra-uterine foetal demise and severe pre-eclampsia and eclampsia. Out of 30 women, 18 (60%) had successful VBAC delivery, 12 (40%) underwent repeat LSCS. 19 cases needed augmentation of labour. Indications for caesarean section were failed induction in 5 (16.6%) women, threatened scar rupture in 3 (10%), non-progress of labour in 2 (6.6%) and meconium stained amniotic fluid in 2 (6.6%). No cases of uterine rupture or maternal mortality was noted in the study.Conclusions: In our study the rate of vaginal birth was 60% without major maternal complications. Hence intracervical Foley’s catheter is an effective, safe and acceptable for labour induction in women with previous caesarean

Effect of smoking on vitamin C and MDA: a cross sectional comparative study

Background: Plasma gets exposed to the gases present in the smoke of the cigarette which leads to peroxidation. The ascorbic acid present in the body gets oxidized there is danger of derangement of lipid profile. The measure of malondialdehyde which is formed in lipid peroxidation reaction is indicative of oxidative stress. Oxidative stress seen among the smokers has been attributed to high MDA levels. Objective was to study the effect of smoking on vitamin C and MDA.Methods: Present study was cross sectional study. Two groups of subjects were compared. Out of 100 study subjects, 25 were non smokers and were kept in one group. Remaining 75 were smokers. These two groups were compared to find out how the smoking habit affects the MDA as well as vitamin C levels among them.Results: The levels of MDA were more in smokers compared to those who did not smoke and this difference was significant. The levels of vitamin C were less in smokers compared to those who did not smoke and this difference was significant (p<0.05). It was found that the MDA levels were significantly more among all degrees of smokers. It was less in smokers with mild degree compared to smokers with heavy or moderate degree. Level of vitamin C was more in non smokers compared to smokers. Mild degree of smokers had better levels of vitamin C compared to moderate degree of smokers.Conclusions: Smoking affects the vitamin C levels and MDA levels in the human body

A study of serum lipid profile in smokers and non-smokers: evaluation of role of smoking on lipid profile

Background: Several studies have reported elevated blood cholesterol levels among persons who regularly smoke cigarettes and lowered blood cholesterol levels among persons quitting smoking. Other studies have also shown that smoking lowers high density lipoprotein level, resulting in an increased risk of coronary heart disease. Smoking also leads to increase in LDL cholesterol and triglyceride levels. The objective was to study serum lipid profile in smokers and non-smokers.Methods: A cross sectional comparative study was carried in 100 subjects. The subjects were divided into two groups. First group consisted of 25 nonsmokers and second group of 75 smokers. The group of 75 smokers was again divided into three equal sub groups of 25 each depending upon the duration and intensity of smoking. Concentration of serum total cholesterol and HDL was determined by Zak’s method. Concentration of serum LDL and VLDL cholesterol was determined by Friedwald’s formula. Concentration of serum triglyceride level was determined by enzymatic end point peroxidase coupled method.Results: All the values of lipid profile i.e., total cholesterol, triglycerides, LDL, VLDL were found to be significantly higher among the smokers compared to the non-smokers. HDL value was significantly lower among smokers. As the degree of smoking increased from mild to heavy smokers, the values of total cholesterol, triglycerides, LDL and VLDL increased. The degree of smoking was inversely proportional to HDL values i.e., the HDL value decreased as the smoking degree increased.Conclusions: Thus, it can be said based on the present study that smoking affects and deranges the lipid profile of the person

Awareness Of Safety Measures In Chemistry Laboratory And Interest In Chemistry Practical Among Xi Standard Students

The purpose of the present investigation was to study the relationship among safety measures in a chemistry laboratory and interest in chemistry practical with reference to some selected variables like gender, area of residence, and medium of instruction. There exists a positive relationship between these two variables safety measures in a chemistry laboratory and interest in chemistry practical

Bis(S-benzyl­isothio­uronium) tetra­chloridozincate(II)

The asymmetric unit of the title compound, (C8H11N2S)2[ZnCl4], contains two S-benzyl­isothio­uronium cations which differ in the C—C—S—C torsion angle [165.3 (2) and 81.9 (2)°] and a tetrahedral tetra­chloridozincate anion. The crystal structure is stabilized by N—H⋯Cl, C—H⋯Cl and C—H⋯S inter­actions

Identification and Analysis of Novel Amino-Acid Sequence Repeats in Bacillus anthracis str. Ames Proteome Using Computational Tools

We have identified four repeats and ten domains that are novel in proteins encoded by the Bacillus anthracis str. Ames proteome using automated in silico methods. A “repeat” corresponds to a region comprising less than 55-amino-acid residues that occur more than once in the protein sequence and sometimes present in tandem. A “domain” corresponds to a conserved region with greater than 55-amino-acid residues and may be present as single or multiple copies in the protein sequence. These correspond to (1) 57-amino-acid-residue PxV domain, (2) 122-amino-acid-residue FxF domain, (3) 111-amino-acid-residue YEFF domain, (4) 109-amino-acid-residue IMxxH domain, (5) 103-amino-acid-residue VxxT domain, (6) 84-amino-acid-residue ExW domain, (7) 104-amino-acid-residue NTGFIG domain, (8) 36-amino-acid-residue NxGK repeat, (9) 95-amino-acid-residue VYV domain, (10) 75-amino-acid-residue KEWE domain, (11) 59-amino-acid-residue AFL domain, (12) 53-amino-acid-residue RIDVK repeat, (13) (a) 41-amino-acid-residue AGQF repeat and (b) 42-amino-acid-residue GSAL repeat. A repeat or domain type is characterized by specific conserved sequence motifs. We discuss the presence of these repeats and domains in proteins from other genomes and their probable secondary structure

Hydrogen bonding and tautomeric equilibria in Schiff bases derived from 2-amino pyridines: electronic spectral evidence for substituent effects

Schiff bases of the type C6H3(R)(OH) CH = NC5H3N(Y)[where R = H, 3-OCH3, 5,6-benzo, 3-CHO-5-CH3,5-CI, 5-Br, 5-CH3, 4-CH3, 3-nitro and 5-nitro and Y=H, 3-CH3 4-CH3, 5-CH3, 6-CH3, 4,6-demethyl and 5-CI) have now been, synthesised and evidence sought for the electronic interaction between the substituents R (in the benzene ring) and Y (in the pyridine ring) in the molecule. The effects of substituents R and Y on the strength of hydrogen bond between OH and CH = N, is coupled to keloenamine &#x21CC; phenoliminc equilibrium. The groups which increase the acidity of the phenolic hydroxyl and the, basicity of the azomethine nitrogen facilitate quinonoid structures with characteristic visible absorption bands in the region 400-600 nm. In those compounds where R = 5,6-benzo, the intensity and the energy of band ~400 nm show a correlation with the electron releasing tendency of Y. Thus there appears an electronic communication between the substituents R and Y causing deviations from the generally accepted model for schiff base structures

SYNTHESIS, CHARACTERIZATION, QUANTITATIVE STRUCTURE-ACTIVITY RELATIONSHIP, DOCKING, ANTIBACTERIAL ACTIVITY, AND BRINE SHRIMP LETHAL STUDIES ON L-PHENYLALANINE SCHIFF BASES

ABSTRACTObjective: Aim of this work is to synthesize and characterization of the hydroxyl group the hydroxyl group substituted L-phenylalanine Schiff basesto compare their predicted quantitative structure-activity relationship (QSAR) and molecular docking against Escherichia coli protein ZipA (1s1j)outcomes with the antibacterial activity and brine shrimp lethal assay (BSLA) results.Methods: The Schiff bases of L-Phenylalanine were synthesized by the simple condensation reaction using methanol, water in 2:1 ratio at reflux andwere characterized by spectral techniques. QSAR parameters of the Schiff bases were predicted using java-based online and offline tools. Moleculardocking carried through online mcule server and CLC Drug Discovery Workbench 3. Antibacterial activity and toxicity studies were conducted usingbroth dilution and brine shrimp lethal assay methods, respectively.Results: The Schiff bases fulfilled the QSAR drug-likeness parameters and showed the docking score between −6.8 and −6.0 Kcal/mol which arehigher than amoxilicillin and gentamicin like standard drugs. They also possess good inhibition for urinary tract infection causing E. coli bacteria,and minimum inhibitory concentrations (MIC) exists between 3.25 and 5.25 μg/ml. The brine shrimp lethal concentration for 50% mortality [LC50])between 58.73 and 135.6 μg/ml.Conclusion: Para, meta and 2,4 hydroxyl substituted Schiff bases exhibited good inhibition against Gram-negative E. coli bacteria at low concentrationand the MIC exists below the LC50 value. The Schiff base showed high drug score, high docking score, and low toxicity than other Schiff base. Dockingscore, high inhibition, low clogP, low MICKeywords: L-phenylalanine, Schiff base, Quantitative structure-activity relationship, Docking, Antibacterial, Lethal concentration for 50% mortality

ZIPRASIDONE HYDROCHLORIDE LOADED NANOSTRUCTURED LIPID CARRIERS (NLCS) FOR INTRANASAL DELIVERY: OPTIMIZATION AND IN VIVO STUDIES

Objective: The present study was an attempt to systemically deliver the most desirable schizophrenia drug, ziprasidone hydrochloride (ZRS) via the intranasal route using nanostructured lipid carrier (NLC) approach. Methods: The desired ZRS loaded NLCs were developed using central composite statistical design and the developed formulation was monitored for improving ZRS bioavailability and their brain targeting efficacy. Results: Pharmacokinetic studies revealed a 10 fold increase (ZRS blood-brain ratio) for NLCs administered through nasal route (in comparison to intravenous route). Similarly, the concentration of ZRS (in the brain) delivered via nasal route exhibits 4 fold increment at all-time points. Conclusion: Therefore, the obtained results suggest a potential nose to brain transport of loaded ZRS by effective bypassing of the Blood-Brain Barrier (BBB)