27 research outputs found
Performance of Molecular Lymphosonography for Detection and Quantification of Metastatic Involvement in Sentinel Lymph Nodes
TEMPORAL TRENDS IN OBESITY AND STATUS OF DYSLIPIDEMIA IN TURKEY: A META-ANALYSIS OF EPIDEMIOLOGICAL STUDIES
86th Congress of the European-Atherosclerosis-Society (EAS) -- MAY 05-08, 2018 -- Lisbon, PORTUGALWOS: 000442512600729European Atherosclerosis So
ASSESSMENT OF THE FRONTAL SINUS DIMENSIONS USING CBCT FOR GENDER DETERMINATION AMONG SAMPLES OF DUTCH AND TURKISH INDIVIDUALS
DATA ON SMOKING IN TURKEY: SYSTEMATIC REVIEW, META-ANALYSIS AND META-REGRESSION OF EPIDEMIOLOGICAL STUDIES ON CARDIOVASCULAR RISK FACTORS
87th Congress of the European-Atherosclerosis-Society (EAS) -- MAY 26-29, 2019 -- Maastricht, NETHERLANDS[Abstract Not Available]European Atherosclerosis So
Tumor apelin immunoreactivity is correlated with body mass index in ovarian high grade serous carcinoma
Factors effecting the model performance measures area under the ROC curve, net reclassification improvement and integrated discrimination improvement
Tumor apelin immunoreactivity is correlated with body mass index in ovarian high grade serous carcinoma
Ovarian cancer has a high mortality rate. Serous carcinoma is the most common subtype and can be detected by distant or lymph node metastasis in advanced stages. Apelin, an adipokine associated with obesity, and its receptor, APJ, participate in lymphatic invasion. Angiogenesis also can affect lymph node involvement in serous ovarian carcinomas. We investigated apelin/APJ receptor immunoreactivity in stages III and IV ovarian cancer with or without lymph node involvement and correlated the results with body mass index (BMI) to determine whether the potential relation of the two affects the outcome of the cancer. We investigated 30 patients diagnosed between 2014 and 2016 with high grade serous ovarian cancer. Tumor:stroma ratio, indirect immunoperoxidase method, H-score and MATLAB analysis were performed. In obese and pre-obese patients, tumor apelin immunoreactivity was stronger than for patients with normal BMI. Tumor:stroma ratio was correlated with survival and lymph node involvement. Strong apelin and moderate APJ immunoreactivity was detected in both lymph node negative and positive patients. BMI was related to both survival outcome and apelin immunoreactivity. BMI, adipokines such as apelin, and the stromal compartment play critical roles in advanced stage serous carcinomas. © 2019, © 2019 The Biological Stain Commission
Decrease in prevalence of hypertension in 15 years: a success story of a population through salt reduction initiatives
European-Society-of-Cardiology Congress -- AUG 25-29, 2018 -- Munich, GERMANY…European Soc Cardio
Decrease in prevalence of hypertension in 15 years: a success story of a population through salt reduction initiatives
European-Society-of-Cardiology Congress -- AUG 25-29, 2018 -- Munich, GERMANYWOS: 000459824004431European Soc Cardio
