Priming attachment security and outgroup humanization: The mediation role of intergroup emotions

Individuals tend to dehumanize the outgroup. In this paper, we explore whether the activation of attachment security can attenuate dehumanization. Two studies were performed. In Study 1, attachment security was primed by showing pictures that depicted relationships with attachment figures; the outgroup was the homeless and humanization was measured considering the attribution of uniquely human and non-uniquely human emotions to this group. In Study 2, the sense of interpersonal security was activated by inviting participants to relive a recent interaction that left them with a feeling of safety and warmth. Outgroup members were the Roma, and humanization was measured considering the attribution of uniquely human and human nature traits to them. In Study 2, the mediation effect of intergroup emotions was investigated. In both studies, outgroup humanization effects were highlighted. In Study 2, these effects were mediated by increased empathy toward the outgroup. Interestingly, the positive impact of security activation was not moderated by chronic attachment orientations. Findings suggest strategies that can be used to improve intergroup relations in specific contexts and in society at large

Surgical treatment of an aseptic fistulized acromioclavicular joint cyst: a case report and review of the literature.

An acromioclavicular joint cyst is an uncommonly reported condition, which seems to result from a massive rotator cuff tear and degenerative osteoarthritis of the acromioclavicular joint. We present the case of an 81-year-old man affected by an acromioclavicular joint cyst, associated to a massive rotator cuff tear, proximal migration of the humeral head and osteoarthritis of the gleno-humeral joint. The mass was 7 x 2.5 cm in size and the overlying skin presented a fistula that drained clear synovial-like fluid. Plain X-ray examination of the left shoulder showed proximal migration of the humeral head migration and osteoarthritis of the gleno-humeral joint, and further MRI evaluation confirmed the clinical diagnosis of a complete rotator cuff tear and observed a large subcutaneous cyst in communication with the degenerative acromioclavicular joint. The patient underwent surgical excision of the cyst and lateral resection of the clavicle to prevent disease recurrence. To the best of our knowledge, this is the first reported case of an acromioclavicular joint cyst complicated by an aseptic fistula resulting from multiple aspirations

A Role for IFITM Proteins in Restriction of Mycobacterium tuberculosis Infection

SummaryThe interferon (IFN)-induced transmembrane (IFITM) proteins are critical mediators of the host antiviral response. Here, we expand the role of IFITM proteins to host defense against intracellular bacterial infection by demonstrating that they restrict Mycobacterium tuberculosis (MTb) intracellular growth. Simultaneous knockdown of IFITM1, IFITM2, and IFITM3 by RNAi significantly enhances MTb growth in human monocytic and alveolar/epithelial cells, whereas individual overexpression of each IFITM impairs MTb growth in these cell types. Furthermore, MTb infection, Toll-like receptor 2 and 4 ligands, and several proinflammatory cytokines induce IFITM1–3 gene expression in human myeloid cells. We find that IFITM3 co-localizes with early and, in particular, late MTb phagosomes, and overexpression of IFITM3 enhances endosomal acidification in MTb-infected monocytic cells. These findings provide evidence that the antiviral IFITMs participate in the restriction of mycobacterial growth, and they implicate IFITM-mediated endosomal maturation in its antimycobacterial activity

Two-dimensional double-quantum spectra reveal collective resonances in an atomic vapor

We report the observation of double-quantum coherence signals in a gas of potassium atoms at twice the frequency of the one-quantum coherences. Since a single atom does not have a state at the corresponding energy, this observation must be attributed to a collective resonance involving multiple atoms. These resonances are induced by weak inter-atomic dipole-dipole interactions, which means that the atoms cannot be treated in isolation, even at a low density of $10^{12}$ cm$^{-3}$

The impact of delays to admission from the emergency department on inpatient outcomes

<p>Abstract</p> <p>Background</p> <p>We sought to determine the impact of delays to admission from the Emergency Department (ED) on inpatient length of stay (LOS), and IP cost.</p> <p>Methods</p> <p>We conducted a retrospective analysis of 13,460 adult (≥ 18 yrs) ED visits between April 1 2006 and March 30 2007 at a tertiary care teaching hospital with two ED sites in which the mode of disposition was admission to ICU, surgery or inpatient wards. We defined ED Admission Delay as ED time to decision to admit > 12 hours. The primary outcomes were IP LOS, and total IP cost.</p> <p>Results</p> <p>Approximately 11.6% (n = 1558) of admitted patients experienced admission delay. In multivariate analysis we found that admission delay was associated with 12.4% longer IP LOS (95% CI 6.6% - 18.5%) and 11.0% greater total IP cost (6.0% - 16.4%). We estimated the cumulative impact of delay on all delayed patients as an additional 2,183 inpatient days and an increase in IP cost of $2,109,173 at the study institution.</p> <p>Conclusions</p> <p>Delays to admission from the ED are associated with increased IP LOS and IP cost. Improving patient flow through the ED may reduce hospital costs and improve quality of care. There may be a business case for investments to reduce emergency department admission delays.</p

Length of tandem repeats in fibrin's αC region correlates with fiber extensibility

The mechanical properties of blood clots are of central importance to hemostasis, thrombosis and embolism. Fibrin fiber networks are the major structural constituent of clots, and numerous studies dating back several decades have characterized their macroscopic viscoelastic properties. The fiber-level and molecular details giving rise to these properties have not been established, however. The correlation between mechanical properties and amino acid sequence is critical for a predictive understanding of the role of genetic defects in clot pathologies. To address this issue, we have developed a nanomanipulation technique for evaluating individual fibrin fibers. It consists of a combination fluorescence/atomic force microscope system that permits viewing of fiber deformation simultaneous with quantitative strain data. Recently we and our colleagues reported on the high extensibility of individual human fibrin fibers, with extensibility (or strain at breaking) of some fibers exceeding 300%, and elastic recovery with strains of up to 180%. This places human fibrin among the most extensible protein polymers, exceeding elastin and resilin in extensibility. Here we test the hypothesis that the majority of the strain is taken up by the tandem repeat segment of the flexible αC region of fibrin. Our study focused on this portion of the protein by mechanically evaluating fibrins with varying lengths of the tandem repeat segment. Using our integrated nanomanipulation system, we stretched individual fibrin fibers made of human, mouse and chicken fibrinogen which have long, intermediate and zero length tandem repeat segments respectively. We found that extensibility correlated with the lengths of the tandem repeat segments

Conductance of Distorted Carbon Nanotubes

We have calculated the effects of structural distortions of armchair carbon nanotubes on their electrical transport properties. We found that the bending of the nanotubes decreases their transmission function in certain energy ranges and leads to an increased electrical resistance. Electronic structure calculations show that these energy ranges contain localized states with significant $\sigma$-$\pi$ hybridization resulting from the increased curvature produced by bending. Our calculations of the contact resistance show that the large contact resistances observed for SWNTs are likely due to the weak coupling of the NT to the metal in side bonded NT-metal configurations.Comment: 5 pages RevTeX including 4 figures, submitted to PR

Single- and multi-walled carbon nanotubes viewed as elastic tubes with Young's moduli dependent on layer number

The complete energy expression of a deformed single-walled carbon nanotube (SWNT) is derived in the continuum limit from the local density approximation model proposed by Lenosky {\it et al.} \lbrack Nature (London) {\bf 355}, 333 (1992)\rbrack and shows to be content with the classic shell theory by which the Young's modulus, the Poisson ratio and the effective wall thickness of SWNTs are obtained as $Y=4.70$TPa, $\nu=0.34$, $h=0.75{\rm \AA}$, respectively. The elasticity of a multi-walled carbon nanotube (MWNT) is investigated as the combination of the above SWNTs of layer distance $d=3.4 {\rm \AA}$ and the Young's modulus of the MWNT is found to be an apparent function of the number of layers, $N$, varying from 4.70TPa to 1.04TPa for N=1 to $\infty$.Comment: 4 pages, 1 figur