22,723 research outputs found
Nonlinear dynamics of a cigar-shaped Bose-Einstein condensate coupled with a single cavity mode
We investigate the nonlinear dynamics of a combined system which is composed
of a cigar-shaped Bose-Einstein condensate and an optical cavity. The two sides
couple dispersively. This system is characterized by its nonlinearity: after
integrating out the freedom of the cavity mode, the potential felt by the
condensate depends on the condensate itself. We develop a discrete-mode
approximation for the condensate. Based on this approximation, we map out the
steady configurations of the system. It is found that due to the nonlinearity
of the system, the nonlinear levels of the system can fold up in some parameter
regimes. That will lead to the breakdown of adiabaticity. Analysis of the
dynamical stability of the steady states indicates that the same level
structure also results in optical bistability.Comment: 8 pages, 5 figure
Vector magnetic field sensing by single nitrogen vacancy center in diamond
In this Letter, we proposed and experimentally demonstrated a method to
detect vector magnetic field with a single nitrogen vacancy (NV) center in
diamond. The magnetic field in parallel with the axis of the NV center can be
obtained by detecting the electron Zeeman shift, while the Larmor precession of
an ancillary nuclear spin close to the NV center can be used to measure the
field perpendicular to the axis. Experimentally, both the Zeeman shift and
Larmor precession can be measured through the fluorescence from the NV center.
By applying additional calibrated magnetic fields, complete information of the
vector magnetic field can be achieved with such a method. This vector magnetic
field detection method is insensitive to temperature fluctuation and it can be
applied to nanoscale magnetic measurement.Comment: 5 pages, 5 figure
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Site Selective Antibody-Oligonucleotide Conjugation via Microbial Transglutaminase.
Nucleic Acid Therapeutics (NATs), including siRNAs and AntiSense Oligonucleotides (ASOs), have great potential to drug the undruggable genome. Targeting siRNAs and ASOs to specific cell types of interest has driven dramatic improvement in efficacy and reduction in toxicity. Indeed, conjugation of tris-GalNAc to siRNAs and ASOs has shown clinical efficacy in targeting diseases driven by liver hepatocytes. However, targeting non-hepatic diseases with oligonucleotide therapeutics has remained problematic for several reasons, including targeting specific cell types and endosomal escape. Monoclonal antibody (mAb) targeting of siRNAs and ASOs has the potential to deliver these drugs to a variety of specific cell and tissue types. However, most conjugation strategies rely on random chemical conjugation through lysine or cysteine residues resulting in conjugate heterogeneity and a distribution of Drug:Antibody Ratios (DAR). To produce homogeneous DAR-2 conjugates with two siRNAs per mAb, we developed a novel two-step conjugation procedure involving microbial transglutaminase (MTGase) tagging of the antibody C-terminus with an azide-functionalized linker peptide that can be subsequently conjugated to dibenzylcyclooctyne (DBCO) bearing oligonucleotides through azide-alkyne cycloaddition. Antibody-siRNA (and ASO) conjugates (ARCs) produced using this strategy are soluble, chemically defined targeted oligonucleotide therapeutics that have the potential to greatly increase the number of targetable cell types
Analytical model of non-Markovian decoherence in donor-based charge quantum bits
We develop an analytical model for describing the dynamics of a donor-based
charge quantum bit (qubit). As a result, the quantum decoherence of the qubit
is analytically obtained and shown to reveal non-Markovian features: The
decoherence rate varies with time and even attains negative values, generating
a non-exponential decay of the electronic coherence and a later recoherence.
The resulting coherence time is inversely proportional to the temperature, thus
leading to low decoherence below a material dependent characteristic
temperature.Comment: 19 pages, 3 figure
Overlap with the Separable State and Phase Transition in the Dicke Model: Zero and Finite Temperature
Overlap with the separable state is introduced in this paper for the purpose
of characterizing the overall correlation in many-body systems. This definition
has clear geometric and physical meaning, and moreover can be considered as the
generalization of the concept-Anderson Orthogonality Catastrophe. As an
exemplification, it is used to mark the phase transition in the Dicke model for
zero and finite temperature. And our discussion shows that it can faithfully
reflect the phase transition properties of this model whether for zero or
finite temperature. Furthermore the overlap for ground state also indicates the
appearance of multipartite entanglement in Dicke model.Comment: 11+ pages. Enlarged version including a formal proof for the method
to find the maximal overlap. accepted by PRA
A semi-analytical perspective on massive galaxies at
The most massive and luminous galaxies in the Universe serve as powerful
probes to study the formation of structure, the assembly of mass, and
cosmology. However, their detailed formation and evolution is still barely
understood. Here we extract a sample of massive mock galaxies from the
semi-analytical model of galaxy formation (SAM) GALACTICUS from the
MultiDark-Galaxies, by replicating the CMASS photometric selection from the
SDSS-III Baryon Oscillation Spectroscopic Survey (BOSS). The comparison of the
GALACTICUS CMASS-mock with BOSS-CMASS data allows us to explore different
aspects of the massive galaxy population at , including the
galaxy-halo connection and the galaxy clustering. We find good agreement
between our modelled galaxies and observations regarding the galaxy-halo
connection, but our CMASS-mock over-estimates the clustering amplitude of the
2-point correlation function, due to a smaller number density compared to BOSS,
a lack of blue objects, and a small intrinsic scatter in stellar mass at fixed
halo mass of dex. To alleviate this problem, we construct an alternative
mock catalogue mimicking the CMASS colour-magnitude distribution by randomly
down-sampling the SAM catalogue. This CMASS-mock reproduces the clustering of
CMASS galaxies within 1 and shows some environmental dependency of star
formation properties that could be connected to the quenching of star formation
and the assembly bias.Comment: 15 pages, 10 figures, 2 tables, submitted to MNRA
Dynamic Behavior of Beijing Sandy Clay and the Dynamic Responses of Beijing Subway to Traffic Vibrations
Experiments were carried out for the Beijing sandy clay using a triaxial apparatus Model DTC- 240 (JAPAN) with the dynamic characteristics of the soil obtained and formulated. The test data were applied to the 2-D and 3-D finite element analyses for the dynamic responses of Beijing Subway to traffic vibrations. Resulte acquired from the numerical analyses happened to be in good coincidence with the measured responses
Controlling suction by vapour equilibrium technique at different temperatures, application to the determination of the water retention properties of MX80 clay
Problems related to unsaturated soils are frequently encountered in
geotechnical or environmental engineering works. In most cases, for the purpose
of simplicity, the problems are studied by considering the suction effects on
volume change or shear strength under isothermal conditions. Under isothermal
condition, very often, a temperature independent water retention curve is
considered in the analysis, which is obviously a simplification. When the
temperature changes are too significant to be neglected, it is necessary to
account for the thermal effects. In this paper, a method for controlling
suction using the vapour equilibrium technique at different temperatures is
presented. First, calibration of various saturated saline solutions was carried
out from temperature of 20 degrees C to 60 degrees C. A mirror psychrometer was
used for the measurement of relative humidity generated by saturated saline
solutions at different temperatures. The results obtained are in good agreement
with the data from the literature. This information was then used to determine
the water retention properties of MX80 clay, which showed that the retention
curve is shifting down with increasing of temperature
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