14,387 research outputs found
Mutual information for examining correlations in DNA
This paper examines two methods for finding whether long-range correlations
exist in DNA: a fractal measure and a mutual information technique. We evaluate
the performance and implications of these methods in detail. In particular we
explore their use comparing DNA sequences from a variety of sources. Using
software for performing in silico mutations, we also consider evolutionary
events leading to long range correlations and analyse these correlations using
the techniques presented. Comparisons are made between these virtual sequences,
randomly generated sequences, and real sequences. We also explore correlations
in chromosomes from different species.Comment: 8 pages, 3 figure
Dynamic polarization of graphene by moving external charges: random phase approximation
We evaluate the stopping and image forces on a charged particle moving
parallel to a doped sheet of graphene by using the dielectric response
formalism for graphene's -electron bands in the random phase approximation
(RPA). The forces are presented as functions of the particle speed and the
particle distance for a broad range of charge-carrier densities in graphene. A
detailed comparison with the results from a kinetic equation model reveal the
importance of inter-band single-particle excitations in the RPA model for high
particle speeds. We also consider the effects of a finite gap between graphene
and a supporting substrate, as well as the effects of a finite damping rate
that is included through the use of Mermin's procedure. The damping rate is
estimated from a tentative comparison of the Mermin loss function with a HREELS
experiment. In the limit of low particle speeds, several analytical results are
obtained for the friction coefficient that show an intricate relationship
between the charge-carrier density, the damping rate, and the particle
distance, which may be relevant to surface processes and electrochemistry
involving graphene.Comment: 14 pages, 10 figures, accepted for publication in Phys. Rev.
Bubbles in a minority game setting with real financial data
© 2005 COPYRIGHT SPIE--The International Society for Optical Engineering Copyright 2005 Society of Photo-Optical Instrumentation Engineers. This paper was published in Complex Systems, edited by Axel Bender, Proc. of SPIE Vol. 6039, 60390C and is made available as an electronic reprint with permission of SPIE. One print or electronic copy may be made for personal use only. Systematic or multiple reproduction, distribution to multiple locations via electronic or other means, duplication of any material in this paper for a fee or for commercial purposes, or modification of the content of the paper are prohibited.It is a well observed fact that markets follow both positive and/or negative trends, crashes and bubble effects. In general a strong positive trend is followed by a crash--a famous example of these effects was seen in the recent crash on the NASDAQ (April 2000) and prior to the crash in the Hong Kong market, which was associated with the Asian crisis in the early 1994. In this paper we use real market data coupled into a minority game with different payoff functions to study the dynamics and the location of financial bubbles.Frédéric D.R. Bonnet, Andrew Allison, and Derek Abbot
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Effect of Brief Biofeedback via a Smartphone App on Stress Recovery: Randomized Experimental Study.
BACKGROUND:Smartphones are often vilified for negatively influencing well-being and contributing to stress. However, these devices may, in fact, be useful in times of stress and, in particular, aid in stress recovery. Mobile apps that deliver evidence-based techniques for stress reduction, such as heart rate variability biofeedback (HRVB) training, hold promise as convenient, accessible, and effective stress-reducing tools. Numerous mobile health apps that may potentially aid in stress recovery are available, but very few have demonstrated that they can influence health-related physiological stress parameters (eg, salivary biomarkers of stress). The ability to recover swiftly from stress and reduce physiological arousal is particularly important for long-term health, and thus, it is imperative that evidence is provided to demonstrate the effectiveness of stress-reducing mobile health apps in this context. OBJECTIVE:The purpose of this research was to investigate the physiological and psychological effects of using a smartphone app for HRVB training following a stressful experience. The efficacy of the gamified Breather component of the Happify mobile health app was examined in an experimental setting. METHODS:In this study, participants (N=140) underwent a laboratory stressor and were randomly assigned to recover in one of three ways: with no phone present, with a phone present, with the HRBV game. Those in the no phone condition had no access to their phone. Those in the phone present condition had their phone but did not use it. Those in the HRVB game condition used the serious game Breather on the Happify app. Stress recovery was assessed via repeated measures of salivary alpha amylase, cortisol, and self-reported acute stress (on a 1-100 scale). RESULTS:Participants in the HRVB game condition had significantly lower levels of salivary alpha amylase during recovery than participants in the other conditions (F2,133=3.78, P=.03). There were no significant differences among the conditions during recovery for salivary cortisol levels or self-reported stress. CONCLUSIONS:These results show that engaging in a brief HRVB training session on a smartphone reduces levels of salivary alpha amylase following a stressful experience, providing preliminary evidence for the effectiveness of Breather in improving physiological stress recovery. Given the known ties between stress recovery and future well-being, this study provides a possible mechanism by which gamified biofeedback apps may lead to better health
Friction force on slow charges moving over supported graphene
We provide a theoretical model that describes the dielectric coupling of a 2D
layer of graphene, represented by a polarization function in the Random Phase
Approximation, and a semi-infinite 3D substrate, represented by a surface
response function in a non-local formulation. We concentrate on the role of the
dynamic response of the substrate for low-frequency excitations of the combined
graphene-substrate system, which give rise to the stopping force on slowly
moving charges above graphene. A comparison of the dielectric loss function
with experimental HREELS data for graphene on a SiC substrate is used to
estimate the damping rate in graphene and to reveal the importance of phonon
excitations in an insulating substrate. A signature of the hybridization
between graphene's pi plasmon and the substrate's phonon is found in the
stopping force. A friction coefficient that is calculated for slow charges
moving above graphene on a metallic substrate shows an interplay between the
low-energy single-particle excitations in both systems.Comment: 13 pages, 5 figures, submitted to Nanotechnology for a special issue
related to the NGC 2009 conference (http://asdn.net/ngc2009/index.shtml
Two Weeks of Ischemic Conditioning Improves Walking Speed and Reduces Neuromuscular Fatigability in Chronic Stroke Survivors
This pilot study examined whether ischemic conditioning (IC), a noninvasive, cost-effective, and easy-to-administer intervention, could improve gait speed and paretic leg muscle function in stroke survivors. We hypothesized that 2 wk of IC training would increase self-selected walking speed, increase paretic muscle strength, and reduce neuromuscular fatigability in chronic stroke survivors. Twenty-two chronic stroke survivors received either IC or IC Sham on their paretic leg every other day for 2 wk (7 total sessions). IC involved 5-min bouts of ischemia, repeated five times, using a cuff inflated to 225 mmHg on the paretic thigh. For IC Sham, the cuff inflation pressure was 10 mmHg. Self-selected walking speed was assessed using the 10-m walk test, and paretic leg knee extensor strength and fatigability were assessed using a Biodex dynamometer. Self-selected walking speed increased in the IC group (0.86 ± 0.21 m/s pretest vs. 1.04 ± 0.22 m/s posttest, means ± SD; P\u3c 0.001) but not in the IC Sham group (0.92 ± 0.47 m/s pretest vs. 0.96 ± 0.46 m/s posttest; P= 0.25). Paretic leg maximum voluntary contractions were unchanged in both groups (103 ± 57 N·m pre-IC vs. 109 ± 65 N·m post-IC; 103 ± 59 N·m pre-IC Sham vs. 108 ± 67 N·m post-IC Sham; P = 0.81); however, participants in the IC group maintained a submaximal isometric contraction longer than participants in the IC Sham group (278 ± 163 s pre-IC vs. 496 ± 313 s post-IC, P = 0.004; 397 ± 203 s pre-IC Sham vs. 355 ± 195 s post-IC Sham; P = 0.46). The results from this pilot study thus indicate that IC training has the potential to improve walking speed and paretic muscle fatigue resistance poststroke
Linewidths in bound state resonances for helium scattering from Si(111)-(1x1)H
Helium-3 spin-echo measurements of resonant scattering from the Si(111)–(1 × 1)H surface, in the energy range 4–14 meV, are presented. The measurements have high energy resolution yet they reveal bound state resonance features with uniformly broad linewidths. We show that exact quantum mechanical calculations of the elastic scattering, using the existing potential for the helium/Si(111)–(1 × 1)H interaction, cannot reproduce the linewidths seen in the experiment. Further calculations rule out inelastic and other mechanisms that might give rise to losses from the elastic scattering channels. We show that corrugation in the attractive part of the atom–surface potential is the most likely origin of the experimental lineshapes
Microstructural characterisation of biocompatible sol-gel derived vanadium doped TiO2 on Ti substrates
Sol-gel derived pure titania is compared with vanadium and / or aluminium modified titania deposited by spin coating on pure titanium substrates annealed at 300C and 650C. Reflection high-energy electron diffraction indicated the presence of anatase from the surface layers of samples annealed at 300C with a transition to rutile with increasing annealing temperature and addition of vanadium. Cross-sectional transmission electron microscopy indicated a gradation of Ti-O phases through the layer with the dominant presence of rutile. Aluminium was found to inhibit grain growth while vanadium promoted crystallisation
Algebraic arctic curves in the domain-wall six-vertex model
The arctic curve, i.e. the spatial curve separating ordered (or `frozen') and
disordered (or `temperate) regions, of the six-vertex model with domain wall
boundary conditions is discussed for the root-of-unity vertex weights. In these
cases the curve is described by algebraic equations which can be worked out
explicitly from the parametric solution for this curve. Some interesting
examples are discussed in detail. The upper bound on the maximal degree of the
equation in a generic root-of-unity case is obtained.Comment: 15 pages, no figures; v2: metadata correcte
A Training Framework and Follow-Up Observations for Multiculturally Inclusive Teaching: Is Believing That We are Emphasizing Diversity Enough?
The authors present a theoretically and empirically grounded training for multiculturally inclusive teaching for new instructors. After implementing this training, qualitative data were gathered from instructors to identify their experience of the training and concerns related to incorporating issues of diversity into their classrooms (Study 1). At the end of the semester immediately following the training, quantitative data were gathered from instructors and their students to examine the interaction between students’ and instructors’ perceived diversity emphasis (Study 2). When allowed to choose the extent to which they incorporated issues of diversity in their classes, the instructors differentially reported emphasizing diversity in class. In addition, results from multi-level linear modeling analyses demonstrated that instructors’ reported emphasis on diversity in the classroom did not predict students’ perceptions of the inclusion of issues of diversity. The authors discuss implications for the development of multiculturally supportive programs of learning at universities
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