Morphisms and pasting of orthoalgebras

We study orthoalgebra morphisms, we show how orthoalgebra monomorphisms and epimorphisms ought to be defined, and we show how orthoalgebras may be" pasted" together to yield new orthoalgebras

THE TWO SCOPES OF FUZZY PROBABILITY THEORY

The aim of this work is to compare between what seems to be entirely different two highly developing “fuzzy probability” theories. The first theory had been developed firstly by statisticians and the other separately by physicists. We start by indicating the needs to develop such theories and what helped to develop each, then we will establish the basis of the two theories and illustrate that each indeed extends classical probability theory. Moreover, we will try to see whether or not any of the two theory can be embedded into the other

Nonstandard Topology on R

Nonstandard topology on is a kind of topology constructed by means of nonstandard analysis on . The ordered field of nonstandard real numbers (or simply hyperreals) has been introduced. It extends the reals . The hyperreals properties and the main topological definitions for with the standard topology have been presented in the nonstandard context. Nonstandard proofs of well-known theorems from the topology on have been given and compared with the standard ones. Keywords Ultrapower, Hyperreals, Transfer Principle, (Nonstandard) Topology on

Access and utilisation of primary health care services comparing urban and rural areas of Riyadh Providence, Kingdom of Saudi Arabia

The Kingdom of Saudi Arabia (KSA) has seen an increase in chronic diseases. International evidence suggests that early intervention is the best approach to reduce the burden of chronic disease. However, the limited research available suggests that health care access remains unequal, with rural populations having the poorest access to and utilisation of primary health care centres and, consequently, the poorest health outcomes. This study aimed to examine the factors influencing the access to and utilisation of primary health care centres in urban and rural areas of Riyadh province of the KSA

Double Sequences and Double Series

This research considers two traditional important questions, which are interesting, at least to most mathematicians. The first question arises in the theory of double sequences of complex numbers, which concerns the relationship, if any, between the following three limits of a double sequence s : N×N −!

Evaluation of Asphaltenes Deposition Inhibition Factors in Heavy Crude Oil Pipelines

Asphaltenes deposition is considered as Achilles’s heel in the oil industry. The nucleation, precipitation and deposition of asphaltenes reduce the production rate significantly in affected wells and sometimes it can completely block the flow by plugging the flowlines, tubing and process facilities, in severe cases. This chapter evaluates the extrinsic and the intrinsic (thermodynamic) factors within the heavy crude oil production system. The main consequences of asphaltenes deposition are discussed such as the solvent-to-crude oil dilution ratio, crude oil physical properties (cloud point, pour point and API gravity), chemical solvent type (carbon number, functional group), agitation time and temperature changes. This chapter is expected to become the means for understanding the factors affecting the asphaltenes nucleation, precipitation and deposition

Modeling focal epileptic activity in the Wilson-Cowan model with depolarization block

Measurements of neuronal signals during human seizure activity and evoked epileptic activity in experimental models suggest that, in these pathological states, the individual nerve cells experience an activity driven depolarization block, i.e. they saturate. We examined the effect of such a saturation in the Wilson–Cowan formalism by adapting the nonlinear activation function; we substituted the commonly applied sigmoid for a Gaussian function. We discuss experimental recordings during a seizure that support this substitution. Next we perform a bifurcation analysis on the Wilson–Cowan model with a Gaussian activation function. The main effect is an additional stable equilibrium with high excitatory and low inhibitory activity. Analysis of coupled local networks then shows that such high activity can stay localized or spread. Specifically, in a spatial continuum we show a wavefront with inhibition leading followed by excitatory activity. We relate our model simulations to observations of spreading activity during seizures

Religiously Grounded Character and Its Association with Subjective Well-Being in Emerging Adults: A Latent Profile Analysis

Subjective Well-Being (SWB) is a central indicator of mental health and overall quality of life in emerging adulthood; religiosity can contribute to this outcome. Emerging research suggests that religious identity and virtues not only can contribute independently to SWB but may work together in shaping it. Given this interplay, the present study adopts a person-centered approach, using Latent Profile Analysis (LPA), to investigate profiles of emerging adults showing a similar configuration of religious identity and virtues and to examine their contribution to SWB. Two-hundred and ninety-one emerging adults living in Italy aged 18 to 30 completed an online survey asking for various demographic variables, religious status, religious affiliation, religious practices, religious identity (U-MICS Religious domain), character strengths and virtues (VIA- IS), and subjective well-being (SWLS and SPANE). A best-fitting model consisting of three distinct, non-overlapping profiles, each demonstrating a unique configuration of religious identity dimensions (commitment, in-depth exploration, reconsideration) and virtues (Transcendence, Humanity, Temperance), emerged. These profiles were differently associated with SWB. Specifically, individuals in the Engaged with High Religious Virtues profile displayed high levels of religious commitment and exploration, paired with high levels of religious virtues, particularly Transcendence, and exhibited the highest levels of SWB. These findings suggest that religious identity and virtues are strictly intertwined and that higher levels of this conjoint integration correspond to greater SWB. Future interventions aimed at fostering religious self-exploration and cultivating religiously grounded virtues can be particularly effective at this stage of the life cycle

Diagnostic and prognostic value of long noncoding RNAs as biomarkers in urothelial carcinoma

Many long noncoding RNAs (lncRNAs) are deregulated in cancer and contribute to oncogenesis. In urothelial carcinoma (UC), several lncRNAs have been reported to be overexpressed and proposed as biomarkers. As most reports have not been confirmed independently in large tissue sets, we aimed to validate the diagnostic and prognostic value of lncRNA upregulation in independent cohorts of UC patients. Thus, expression of seven lncRNA candidates (GAS5, H19, linc-UBC1, MALAT1, ncRAN, TUG1, UCA1) was measured by RT-qPCR in cell lines and tissues and correlated to clinicopathological parameters including follow-up data (set 1: N n = 10; T n = 106). Additionally, publicly available TCGA data was investigated for differential expression in UC tissues (set 2: N n = 19; T n = 252,) and correlation to overall survival (OS). All proposed candidates tended to be upregulated in tumour tissues, with the exception of MALAT1, which was rather diminished in cancer tissues of both data sets. However, strong overexpression was generally limited to individual tumour tissues and statistically significant overexpression was only observed for UCA1, TUG1, ncRAN and linc-UBC1 in tissue set 2, but for no candidate in set 1. Altered expression of individual lncRNAs was associated with overall survival, but not consistently between both patient cohorts. Interestingly, lower expression of TUG1 in a subset of UC patients with muscle-invasive tumours was significantly correlated with worse OS in both cohorts. Further analysis revealed that tumours with low TUG1 expression are characterized by a basal-squamous-like subtype signature accounting for the association with poor outcome. In conclusion, our study demonstrates that overexpression of the candidate lncRNAs is found in many UC cases, but does not occur consistently and strongly enough to provide reliable diagnostic or prognostic value as an individual biomarker. Subtype-dependent expression patterns of lncRNAs like TUG1 could become useful to stratify patients by molecular subtype, thus aiding personalized treatments