8,479 research outputs found
On the ultraviolet behaviour of quantum fields over noncommutative manifolds
By exploiting the relation between Fredholm modules and the
Segal-Shale-Stinespring version of canonical quantization, and taking as
starting point the first-quantized fields described by Connes' axioms for
noncommutative spin geometries, a Hamiltonian framework for fermion quantum
fields over noncommutative manifolds is introduced. We analyze the ultraviolet
behaviour of second-quantized fields over noncommutative 3-tori, and discuss
what behaviour should be expected on other noncommutative spin manifolds.Comment: 10 pages, RevTeX version, a few references adde
Gender assessment through three-dimensional analysis of maxillary sinuses by means of Cone Beam Computed Tomography
OBJECTIVE:
The availability of a low dose radiation technology such as Cone Beam Computed Tomography (CBCT) in dental practice has increased the number of scans available for forensic purposes. Moreover, specific software allows for three-dimensional (3D) characterization of the maxillary sinuses. This study was performed to determine whether sinus maxillary volumes can be useful to identify gender after validating the use of the Dolphin software as a tool for volumetric estimation of maxillary sinus volumes.
PATIENTS AND METHODS:
The validation was performed by four different operators measuring the volume of six phantoms, where the real volume was already known. The maxillary sinus volumes of 52 patients (26 males and 26 females) mean age 24.3 were calculated and compared between genders and sagittal skeletal class subdivision. The measurements for patients and phantoms were based on CBCT scans (ILUMA™) processed by Dolphin 3D software.
RESULTS:
No statistical difference was observed between the real volume and the volume measurements performed by the operators. No statistical difference was found in patient's maxillary sinus volumes between gender.
CONCLUSIONS:
Based on our results, it is not possible to support the use of maxillary sinuses to discern sexual difference in corpse identification
No more time to stay ‘single’ in the detection of Anisakis pegreffii, A. simplex (s. s.) and hybridization events between them: a multi-marker nuclear genotyping approach
A multi-marker nuclear genotyping approach was performed on larval and adult specimens of Anisakis spp. (N = 689) collected from fish and cetaceans in allopatric and sympatric areas of the two species Anisakis pegreffii and Anisakis simplex
(s. s.), in order to: (1) identify specimens belonging to the parental taxa by using nuclear markers (allozymes loci) and sequence analysis of a new diagnostic nuclear DNA locus (i.e. partial sequence of the EF1 α−1 nDNA region) and (2) recognize hybrid categories. According to the Bayesian clustering algorithms, based on those markers, most of the individuals
(N = 678) were identified as the parental species [i.e. A. pegreffii or A. simplex (s. s.)], whereas a smaller portion (N = 11)
were recognized as F1 hybrids. Discordant results were obtained when using the polymerase chain reaction–restriction
fragment length polymorphisms (PCR–RFLPs) of the internal transcribed spacer (ITS) ribosomal DNA (rDNA) on
the same specimens, which indicated the occurrence of a large number of ‘hybrids’ both in sympatry and allopatry.
These findings raise the question of possible misidentification of specimens belonging to the two parental Anisakis and
their hybrid categories derived from the application of that single marker (i.e. PCR–RFLPs analysis of the ITS of
rDNA). Finally, Bayesian clustering, using allozymes and EF1 α−1 nDNA markers, has demonstrated that hybridization
between A. pegreffii and A. simplex (s. s.) is a contemporary phenomenon in sympatric areas, while no introgressive hybridization takes place between the two species
Mortalità per sclerosi multipla nella regione Toscana
OBIETTIVI: Valutare il trend di mortalità per Sclerosi Multipla (SM) in Toscana nel ventennio 1987-2006.
METODI: I dati sulla mortalità per SM sono stati ottenuti consultando gli archivi informatici delle schede di morte presso l’Agenzia Regionale di Sanità Toscana. I dati raccolti sono stati suddivisi per i quattro quinquenni compresi tra il 1987 e il 2006: (1987-1991), (1992-1996), (1997-2001), (2002-2006). Sono stati calcolati i tassi standardizzati di mortalità (metodo di standardizzazione diretta) per SM rispetto alla popolazione toscana del 2000 e i tassi di mortalità per SM specifici per sesso ed età.
RISULTATI: I tassi standardizzati di mortalità con causa SM calcolati per ogni anno mostrano una diminuzione della mortalità, in entrambi i sessi, particolarmente marcata nel primo quinquennio (1987-1991). Per i maschi si osserva, nei quattro quinquenni analizzati, un trend decrescente dei tassi di mortalità che va da 0,61 per il quinquennio 1987-1991 a 0,42 per 100.000 per quello 2002-2006. Analogamente per le femmine si osserva una diminuzione da 1,29 a 0,60 per 100.000.
Analizzando i tassi di mortalità per SM specifici per età abbiamo osservato un picco della mortalità nei maschi in corrispondenza della fascia di età 75-79 anni, mentre nelle donne nella fascia 65-69 anni. In entrambi i sessi il numero dei decessi aumenta fortemente dopo i 45 anni e diminuisce dopo i 79 anni. Considerando l’età di esordio, che andava dai 25 ai 35 anni, e la sopravvivenza delle persone, pari a 30-35 anni dalla diagnosi, la mortalità maggiore si riscontra nelle fasce di età da noi osservate.
CONCLUSIONI: A causa della piccola dimensione del campione, tutti i valori vanno interpretati con cautela, ma i dati presenti in letteratura sono in accordo con i dati osservati nel nostro studio relativi al primo quinquennio. Infatti, il decremento di mortalità nel periodo 1987-1991 è in linea con i dati precedentemente pubblicati in uno studio sulla mortalità per SM in Italia dal 1974 al 1993 (Tassinari, 2001). Per gli anni successivi non esistono dati in letteratura relativi alla mortalità per SM in Italia.
La mortalità più elevata nelle femmine riflette il maggior numero di casi di SM nella popolazione femminile ed è supportata anche dai dati presenti in letteratura sia in Italia che all’estero (Massey e Schoenberg, 1982). La mortalità per SM osservata nel nostro studio è presumibilmente una sottostima poiché talvolta l’SM non viene indicata come causa di morte
High-order dispersion effects in two-photon interference
Two-photon interference and Hong-Ou-Mandel (HOM) effect are relevant tools
for quantum metrology and quantum information processing. In optical coherence
tomography, HOM effect is exploited to achieve high-resolution measurements
with the width of the HOM dip being the main parameter. On the other hand,
applications like dense coding require high-visibility performances. Here we
address high-order dispersion effects in two-photon interference and study,
theoretically and experimentally, the dependence of the visibility and the
width of the HOM dip on both the pump spectrum and the downconverted photon
spectrum. In particular, a spatial light modulator is exploited to
experimentally introduce and manipulate a custom phase function to simulate the
high-order dispersion effects
Report 1 PHIN-CARE-JRA2-WP3 Second Task: Pulse Shaping
This report presents the activity developed on laser pulse shaping argument in years 2004-2005 by Milano-INFN within the framework of CARE /JRA2 \Charge production with Photoinjectors"
second task \Pulse Shaping". A dedicated laser system with the relative diagnostic
tools have been developed. A liquid crystal programmable spatial light modulator(LCP-SLM)
shaper have been studied and set for the generation of di®erent waveforms. The shaper is
integrated in the laser system for an automatic generation of the target waveforms via the
insetion of a computer which drives the system through the developed software. The system
can be programmed to generate any target waveform compatible with the spectral bandwidth
of the laser system and some exemples are presented. The following issues are treated: (i)
the operation stability as function of perturbations of the set-up parameters, (ii) the design
of the shaper for the SPARC project, (iii) a new shaper concept for the generation of long
target waveforms and (iiii) the rectangular pulse generation at the second harmonic
Fredholm Modules on P.C.F. Self-Similar Fractals and their Conformal Geometry
The aim of the present work is to show how, using the differential calculus
associated to Dirichlet forms, it is possible to construct Fredholm modules on
post critically finite fractals by regular harmonic structures. The modules are
d-summable, the summability exponent d coinciding with the spectral dimension
of the generalized laplacian operator associated with the regular harmonic
structures. The characteristic tools of the noncommutative infinitesimal
calculus allow to define a d-energy functional which is shown to be a
self-similar conformal invariant.Comment: 16 page
Optical interferometry in the presence of large phase diffusion
Phase diffusion represents a crucial obstacle toward the implementation of high-precision interferometric measurements and phase-shift-based communication channels. Here we present a nearly optimal interferometric scheme based on homodyne detection and coherent signals for the detection of a phase shift in the presence of large phase diffusion. In our scheme the ultimate bound to interferometric sensitivity is achieved already for a small number of measurements, of the order of hundreds, without using nonclassical light
What guidance are researchers given on how to present network meta-analyses to end-users such as policymakers and clinicians? A systematic review
© 2014 Sullivan et al. This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.Introduction: Network meta-analyses (NMAs) are complex methodological approaches that may be challenging for non-technical end-users, such as policymakers and clinicians, to understand. Consideration should be given to identifying optimal approaches to presenting NMAs that help clarify analyses. It is unclear what guidance researchers currently have on how to present and tailor NMAs to different end-users. Methods: A systematic review of NMA guidelines was conducted to identify guidance on how to present NMAs. Electronic databases and supplementary sources were searched for NMA guidelines. Presentation format details related to sample formats, target audiences, data sources, analysis methods and results were extracted and frequencies tabulated. Guideline quality was assessed following criteria developed for clinical practice guidelines. Results: Seven guidelines were included. Current guidelines focus on how to conduct NMAs but provide limited guidance to researchers on how to best present analyses to different end-users. None of the guidelines provided reporting templates. Few guidelines provided advice on tailoring presentations to different end-users, such as policymakers. Available guidance on presentation formats focused on evidence networks, characteristics of individual trials, comparisons between direct and indirect estimates and assumptions of heterogeneity and/or inconsistency. Some guidelines also provided examples of figures and tables that could be used to present information. Conclusions: Limited guidance exists for researchers on how best to present NMAs in an accessible format, especially for non-technical end-users such as policymakers and clinicians. NMA guidelines may require further integration with end-users' needs, when NMAs are used to support healthcare policy and practice decisions. Developing presentation formats that enhance understanding and accessibility of NMAs could also enhance the transparency and legitimacy of decisions informed by NMAs.The Canadian Institute of Health Research (CIHR) Drug Safety and Effectiveness Network (Funding reference number – 116573)
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