Evaluation of Overlay/underlay Waveform via SD-SMSE Framework for Enhancing Spectrum Efficiency

Recent studies have suggested that spectrum congestion is mainly due to the inefficient use of spectrum rather than its unavailability. Dynamic Spectrum Access (DSA) and Cognitive Radio (CR) are two terminologies which are used in the context of improved spectrum efficiency and usage. The DSA concept has been around for quite some time while the advent of CR has created a paradigm shift in wireless communications and instigated a change in FCC policy towards spectrum regulations. DSA can be broadly categorized as using a 1) Dynamic Exclusive Use Model, 2) Spectrum Commons or Open sharing model or 3) Hierarchical Access model. The hierarchical access model envisions primary licensed bands, to be opened up for secondary users, while inducing a minimum acceptable interference to primary users. Spectrum overlay and spectrum underlay technologies fall within the hierarchical model, and allow primary and secondary users to coexist while improving spectrum efficiency. Spectrum overlay in conjunction with the present CR model considers only the unused (white) spectral regions while in spectrum underlay the underused (gray) spectral regions are utilized. The underlay approach is similar to ultra wide band (UWB) and spread spectrum (SS) techniques utilize much wider spectrum and operate below the noise floor of primary users. Software defined radio (SDR) is considered a key CR enabling technology. Spectrally modulated, Spectrally encoded (SMSE) multi-carrier signals such as Orthogonal Frequency Domain Multiplexing (OFDM) and Multi-carrier Code Division Multiple Access (MCCDMA) are hailed as candidate CR waveforms. The SMSE structure supports and is well-suited for SDR based CR applications. This work began by developing a general soft decision (SD) CR framework, based on a previously developed SMSE framework that combines benefits of both the overlay and underlay techniques to improve spectrum efficiency and maximizing the channel capacity. The resultant SD-SMSE framework provides a user with considerable flexibility to choose overlay, underlay or hybrid overlay/underlay waveform depending on the scenario, situation or need. Overlay/Underlay SD-SMSE framework flexibility is demonstrated by applying it to a family of SMSE modulated signals such as OFDM, MCCDMA, Carrier Interferometry (CI) MCCDMA and Transform Domain Communication System (TDCS). Based on simulation results, a performance analysis of Overlay, Underlay and hybrid Overlay/Underlay waveforms are presented. Finally, the benefits of combining overlay/underlay techniques to improve spectrum efficiency and maximize channel capacity are addressed

Cost and Consequences of Sedentary Living: New Battleground for an Old Enemy

The purpose of this review is to update our earlier review by itemizing, as best we can, the costs and consequences of sedentary living, and thus provide cost reasons to fight a war against sedentary lifestyles

Polymorphisms in ARMS2/HTRA1 and complement genes and age-related macular degeneration in India: findings from the INDEYE study.

PURPOSE: Association between genetic variants in complement factor H (CFH), factor B (CFB), component 2 (C2), and in the ARMS2/HTRA1 region with age-related macular degeneration (AMD) comes mainly from studies of European ancestry and case-control studies of late-stage disease. We investigated associations of both early and late AMD with these variants in a population-based study of people aged 60 years and older in India. METHODS: Fundus images were graded using the Wisconsin Age-Related Maculopathy Grading System and participants assigned to one of four mutually exclusive stages based on the worse affected eye (0 = no AMD, 1-3 = early AMD, 4 = late AMD). Multinomial logistic regression was used to derive risk ratios (RR) accounting for sampling method and adjusting for age, sex, and study center. RESULTS: Of 3569 participants, 53.2% had no signs of amd, 45.6% had features of early amd, and 1.2% had late amd. CFH (RS1061170), C2 (RS547154), OR CFB (RS438999) was not associated with early or late AMD. In the ARMS2 locus, RS10490924 was associated with both early (adjusted RR 1.22, 95% confidence interval [CI]: 1.13-1.33, P < 0.0001) and late AMD (adjusted RR 1.81, 95% CI: 1.15-2.86; P = 0.01); rs2672598 was associated only with early AMD (adjusted RR 1.12, 95% CI: 1.02-1.23; P = 0.02); rs10490923 was not associated with early or late AMD. CONCLUSIONS: Two variants in ARMS2/HTRA1 were associated with increased risk of early AMD, and for one of these, the increased risk was also evident for late AMD. The study provides new insights into the role of these variants in early stages of AMD in India

Consistent Anisotropic Repulsions for Simple Molecules

We extract atom-atom potentials from the effective spherical potentials that suc cessfully model Hugoniot experiments on molecular fluids, e.g., $O_2$ and $N_2$. In the case of $O_2$ the resulting potentials compare very well with the atom-atom potentials used in studies of solid-state propertie s, while for $N_2$ they are considerably softer at short distances. Ground state (T=0K) and room temperatu re calculations performed with the new $N-N$ potential resolve the previous discrepancy between experimental and theoretical results.Comment: RevTeX, 5 figure

Objective structured practical examination (OSPE) as a tool in formative assessment of II MBBS students, in pathology

Background: Assessment drives the student learning. Regular periodical assessment not only improves learning habits, but also enhances the competence in all levels of medical education. Traditional practical examination is more subjective. It depends on examiners subjectivity, varying difficulty level of various experiments, and also internal marks variation etc. These flaws can be overcome by newer methods like OSPE. The aim of the study was to implement OSPE as a tool of internal assessment for practical skills in the II MBBS. To compare this with traditional practical examination (TPE). To obtain the students and faculty feedback regarding OSPE as a tool of assessment.Methods: A cross sectional study was carried out for 158 students in II internal pathology practical examination for six days in the second week of September 2016 at Department of Pathology, Dr. Pinnamaneni Siddhartha institute of medical sciences & Research Foundation, Chinnaoutpalli. Faculty and students were sensitized; blueprint were used to arrange twenty OSPE stations for the exercises conducted as per TPE and for the same 25 marks as per TPE. Simultaneously, all the students were subjected to both TPE and OSPE at the same time and venue. TPE was assessed by two professors and OSPE by separate eight faculty members independently without interaction with the students. The procedural stations were evaluated by using checklist and the response stations which consisted of short answers and MCQs, facilitated correction. Feedback was given to the student on their performance and feedback was obtained from the students and faculty regarding OSPE by questionnaire with Yes/No answers.Results: Performance score of students in OPSE (13.73 ±2.49) was higher as compared to TPE (9.27±1.86) which was statistically significant. Based on the response to the questionnaire, students perception towards OSPE was analyzed. Majority strongly agree OSPE to be fairer, more transparent and objective in comparison to TPE. In contrast, all the faculty members unanimously opined that OSPE was difficult to arrange, time taken and faculty versus students ratio was high for evaluation. Though, the faculty (91%) overall opined that OSPE should be included as a method of assessment.Conclusions: Present study revealed that OSPE was acceptable, feasible and reliable to the students as well as for faculty for the internal assessment in pathology. Opinions of both students and faculties strongly agreed that OPSE is more effective objective assessment tool