1,570 research outputs found

    Calculation of resonances in the Coulomb three-body system with two disintegration channels in the adiabatic hyperspherical approach

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    The method of calculation of the resonance characteristics is developed for the metastable states of the Coulomb three-body (CTB) system with two disintegration channels. The energy dependence of K-matrix in the resonance region is calculated with the use of the stabilization method. Resonance position and partial widths are obtained by fitting the numerically calculated K(E)-matrix with the help of the generalized Breit-Wigner formula.Comment: Latex, 11 pages with 5 figures and 2 table

    Stochastic inequalities for single-server loss queueing systems

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    The present paper provides some new stochastic inequalities for the characteristics of the M/GI/1/nM/GI/1/n and GI/M/1/nGI/M/1/n loss queueing systems. These stochastic inequalities are based on substantially deepen up- and down-crossings analysis, and they are stronger than the known stochastic inequalities obtained earlier. Specifically, for a class of GI/M/1/nGI/M/1/n queueing system, two-side stochastic inequalities are obtained.Comment: 17 pages, 11pt To appear in Stochastic Analysis and Application

    Lipid peroxidation is essential for α-synuclein-induced cell death.

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    Parkinson's disease is the second most common neurodegenerative disease and its pathogenesis is closely associated with oxidative stress. Deposition of aggregated α-synuclein (α-Syn) occurs in familial and sporadic forms of Parkinson's disease. Here, we studied the effect of oligomeric α-Syn on one of the major markers of oxidative stress, lipid peroxidation, in primary co-cultures of neurons and astrocytes. We found that oligomeric but not monomeric α-Syn significantly increases the rate of production of reactive oxygen species, subsequently inducing lipid peroxidation in both neurons and astrocytes. Pre-incubation of cells with isotope-reinforced polyunsaturated fatty acids (D-PUFAs) completely prevented the effect of oligomeric α-Syn on lipid peroxidation. Inhibition of lipid peroxidation with D-PUFAs further protected cells from cell death induced by oligomeric α-Syn. Thus, lipid peroxidation induced by misfolding of α-Syn may play an important role in the cellular mechanism of neuronal cell loss in Parkinson's disease. We have found that aggregated α-synuclein-induced production of reactive oxygen species (ROS) that subsequently stimulates lipid peroxidation and cell death in neurons and astrocytes. Specific inhibition of lipid peroxidation by incubation with reinforced polyunsaturated fatty acids (D-PUFAs) completely prevented the effect of α-synuclein on lipid peroxidation and cell death

    Cross sections for geodesic flows and \alpha-continued fractions

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    We adjust Arnoux's coding, in terms of regular continued fractions, of the geodesic flow on the modular surface to give a cross section on which the return map is a double cover of the natural extension for the \alpha-continued fractions, for each α\alpha in (0,1]. The argument is sufficiently robust to apply to the Rosen continued fractions and their recently introduced \alpha-variants.Comment: 20 pages, 2 figure

    THE DEVELOPMENT OF METHOD AND ON-BOARD DEVICES FOR COLLISION AVOIDANCE WHEN OVERTAKING

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    A method for improving the safety of overtaking maneuver by using the on-board collision avoidance system, which has an increased assessment reliability of safety of vehicles overtaking that move in the same direction is offered. The proposed system takes into account the main factors that affect the overtaking maneuver

    Multi-level Dynamical Systems: Connecting the Ruelle Response Theory and the Mori-Zwanzig Approach

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    In this paper we consider the problem of deriving approximate autonomous dynamics for a number of variables of a dynamical system, which are weakly coupled to the remaining variables. In a previous paper we have used the Ruelle response theory on such a weakly coupled system to construct a surrogate dynamics, such that the expectation value of any observable agrees, up to second order in the coupling strength, to its expectation evaluated on the full dynamics. We show here that such surrogate dynamics agree up to second order to an expansion of the Mori-Zwanzig projected dynamics. This implies that the parametrizations of unresolved processes suited for prediction and for the representation of long term statistical properties are closely related, if one takes into account, in addition to the widely adopted stochastic forcing, the often neglected memory effects.Comment: 14 pages, 1 figur
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