7,236 research outputs found
Tablet computers in assessing performance in a high stakes exam : opinion matters
The authors would like to thank Dr Craig brown, University of Aberdeen for assistance with data analysis.Peer reviewedPublisher PD
Immunity as the predominant factor determining metastasis by murine lymphomas.
The metastatic behaviour of the L5178E (non-M) lymphoma and a highly metastatic subline L51787ES (M) were studied in syngeneic DBA2 mice. The non-M tumour rarely metastasizes in intact syngeneic mice, but produces extensive and rapidly lethal metastases when implanted into irradiated recipients. The metastatic behaviour of the M subline is unaffected by irradiation of the host. By conventional transplantation criteria, the non-M tumour is more immunogenic than the M subline. Both tumours, however, produce similar responses in a lymphnode weight-gain assay. Host-cell infiltration of the tumours growing s.c. is much greater in the non-M than the M, the infiltrating cells being Fc-receptor-positive and maturing into macrophages after 2 days in vitro. Although spontaneous in vitro motility of the M cells is much greater than that of the non-M, the metastatic behaviour of the tumours is clearly determined by host immunological responses
Seeing statistics at the upgraded 3.8m UK infrared telescope (UKIRT)
From 1991 until 1997, the 3.8m UK Infrared Telescope (UKIRT) underwent a
programme of upgrades aimed at improving its intrinsic optical performance.
This resulted in images with a FWHM of 0."17 at 2.2 um in September 1998. To
understand and maintain the improvements to the delivered image quality since
the completion of the upgrades programme, we have regularly monitored the
overall atmospheric seeing, as measured by radial displacements of subaperture
images (i.e. seeing-generated focus fluctuations), and the delivered image
diameters. The latter have been measured and recorded automatically since the
beginning of 2001 whenever the facility imager UFTI (UKIRT Fast Track Imager)
has been in use.
In this paper we report the results of these measurements. We investigate the
relation between the delivered image diameter and the RMS atmospheric seeing
(as measured by focus fluctuations, mentioned above). We find that the best
seeing occurs in the second half of the night, generally after 2am HST and that
the best seeing occurs in the summer between the months of July and September.
We also find that the relationship between Zrms and delivered image diameter is
uncertain. As a result Zrms frequently predicts a larger FWHM than that
measured in the images.
Finally, we show that there is no correlation between near-infrared seeing
measured at UKIRT and sub-mm seeing measured at the Caltech Submillimetre
Observatory (CSO).Comment: 10 pages to appear in the SPIE proceeding vol. 4484 on Observatory
Operations to Maximize Scientific Retur
THYMOCYTES FROM MICE IMMUNIZED AGAINST AN ALLOGRAFT RENDER BONE-MARROW CELLS SPECIFICALLY CYTOTOXIC
Thymocytes from C57BL mice immunized with the DBA/2 lymphoma L5178Y exert in vitro an immunologically specific cytotoxic action against the target cells in the presence of bone-marrow cells. Neither the nonimmune bone marrow nor the immune thymocytes are by themselves cytotoxic. The cells in the bone marrow which take part in the cytotoxic action adhere to glass and are sensitive to anti-macrophage serum. These bone-marrow cells can also be rendered specifically cytotoxic by exposure to the supernatant obtained from a culture of immune thymocytes with the specific target cells. The thymocytes before they are confronted with the specific target cells are very radiosensitive; however, on coming into contact with the target cells, an immunologically specific increase in RNA synthesis occurs and thereafter the thymocytes' capacity to render bone-marrow cells cytotoxic is relatively radioresistant. Two classes of immune lymphocytes occur in mice immunized with allogeneic cells, those that are capable of killing target cells directly and those that produce a factor capable of rendering macrophages (or monocytes) specifically cytotoxic. In the thymus of immune animals only the latter are found while both categories are present in the spleen and lymph nodes of immune animals
Hamiltonian Formulation of Two Body Problem in Wheeler-Feynman electrodynamics
A Hamiltonian formulation for the classical problem of electromagnetic
interaction of two charged relativistic particles is found.Comment: 22 pages, 8 Uuencoded Postscript figure
Seeing motion and apparent motion
In apparent motion experiments, participants are presented with what is in fact a succession of two brief stationary stimuli at two different locations, but they report an impression of movement. Philosophers have recently debated whether apparent motion provides evidence in favour of a particular account of the nature of temporal experience. I argue that the existing discussion in this area is premised on a mistaken view of the phenomenology of apparent motion and, as a result, the space of possible philosophical positions has not yet been fully explored. In particular, I argue that the existence of apparent motion is compatible with an account of the nature of temporal experience that involves a version of direct realism. In doing so, I also argue against two other claims often made about apparent motion, viz. that apparent motion is the psychological phenomenon that underlies motion experience in the cinema, and that apparent motion is subjectively indistinguishable from real motion
On the General Ericksen-Leslie System: Parodi's Relation, Well-posedness and Stability
In this paper we investigate the role of Parodi's relation in the
well-posedness and stability of the general Ericksen-Leslie system modeling
nematic liquid crystal flows. First, we give a formal physical derivation of
the Ericksen-Leslie system through an appropriate energy variational approach
under Parodi's relation, in which we can distinguish the
conservative/dissipative parts of the induced elastic stress. Next, we prove
global well-posedness and long-time behavior of the Ericksen-Leslie system
under the assumption that the viscosity is sufficiently large. Finally,
under Parodi's relation, we show the global well-posedness and Lyapunov
stability for the Ericksen-Leslie system near local energy minimizers. The
connection between Parodi's relation and linear stability of the
Ericksen-Leslie system is also discussed
Confirmation of the planet around HD 95086 by direct imaging
VLT/NaCo angular differential imaging at L' (3.8 microns) revealed a probable
giant planet comoving with the young and early-type HD 95086 also known to
harbor an extended debris disk. The discovery was based on the proper motion
analysis of two datasets spanning 15 months. However, the second dataset
suffered from bad atmospheric conditions, which limited the significance of the
redetection at the 3 sigma level. In this Letter, we report new VLT/NaCo
observations of HD 95086 obtained on 2013 June 26-27 at L' to recover the
planet candidate. We unambiguously redetect the companion HD 95086 b with
multiple independent pipelines at a signal-to-noise ratio greater than or equal
to 5. Combined with previously reported measurements, our astrometry decisively
shows that the planet is comoving with HD 95086 and inconsistent with a
background object. With a revised mass of 5 pm 2 Jupiter masses, estimated from
its L' photometry and "hot-start" models at 17 pm 4 Myr, HD 95086 b becomes a
new benchmark for further physical and orbital characterization of young giant
planets.Comment: accepted for publication to AP
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