12,683 research outputs found

    Uncoordinated cooperative forwarding in vehicular networks with random transmission range

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    © 2015 IEEE. This paper investigates cooperative forwarding in large highly dynamic vehicular networks. Unlike traditional coordinated cooperative forwarding schemes that require a large amount of coordination information to be exchanged before making the forwarding decision, this paper proposes an uncoordinated cooperative forwarding scheme where each node, a random transmission range, decides whether or not to forward a received packet independently based on a forwarding probability determined by its own location. Analytical results are derived on the successful end-to-end transmission probability and the expected number of forwarding nodes involved in the cooperative forwarding process. The multi-hop correlations and multi-path correlations, which constitute major challenges in the analysis, are carefully considered in our analysis. Simulations are conducted to establish the performance of the proposed scheme assuming different forwarding probability functions. In addition to developing an uncoordinated cooperative forwarding scheme, which is particularly suited for the highly dynamic vehicular networks, this paper also makes important theoretical contributions on analyzing the connectivity of networks with nodes of variable and random transmission ranges

    Interference-constrained adaptive simultaneous spectrum sensing and data transmission scheme for unslotted cognitive radio network

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    Cognitive radio (CR) is widely recognized as a novel approach to improve the spectrum efficiency. However, there exists one problem needed to be resolved urgently, that is the two conflicting goals in CR network: one is to minimize the interference to primary (licensed) system; the other is to maximize the throughput of secondary (unlicensed) system. Meanwhile, the secondary user (SU) has to monitor the spectrum continuously to avoid the interference to primary user (PU), thus the throughput of the secondary system is affected by how often and how long the spectrum sensing is performed. Aiming to balance the two conflicting goals, this article proposes a novel Interference-Constrained Adaptive Simultaneous spectrum Sensing and data Transmission (ICASST) scheme for unslotted CR network, where SUs are not synchronized with PUs. In the ICASST scheme, taking advantage of the statistic information of PU's activities, the data transmission time is adaptively adjusted to avoid the interference peculiar to unslotted CR network; the operation of spectrum sensing is moved to SU receiver from SU transmitter to increase the data transmission time and hence improve the throughput of SU. Simulation results validate the efficiency of ICASST scheme, which significantly increases the throughput of secondary system and decreases the interference to PU simultaneously. © 2012 Yang et al

    Study on utilization of carboxyl group decorated carbon nanotubes and carbonation reaction for improving strengths and microstructures of cement paste

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    Carbon nanotubes (CNTs) have excellent mechanical properties and can be used to reinforce cement-based materials. On the other hand, the reaction product of carbonation with hydroxides in hydrated cement paste can reduce the porosity of cement-based materials. In this study, a novel method to improve the strength of cement paste was developed through a synergy of carbon nanotubes decorated with carboxyl group and carbonation reactions. The experimental results showed that the carboxyl group (–COOH) of decorated carbon nanotubes and the surfactant can control the morphology of the calcium carbonate crystal of carbonation products in hydrated cement paste. The spindle-like calcium carbonate crystals showed great morphological differences from those observed in the conventional carbonation of cement paste. The spindle-like calcium carbonate crystals can serve as fiber-like reinforcements to reinforce the cement paste. By the synergy of the carbon nanotubes and carbonation reactions, the compressive and flexural strengths of cement paste were significantly improved and increased by 14% and 55%, respectively, when compared to those of plain cement paste

    Tick-borne encephalitis virus induces chemokine RANTES expression via activation of IRF-3 pathway.

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    BACKGROUND: Tick-borne encephalitis virus (TBEV) is one of the most important flaviviruses that targets the central nervous system (CNS) and causes encephalitides in humans. Although neuroinflammatory mechanisms may contribute to brain tissue destruction, the induction pathways and potential roles of specific chemokines in TBEV-mediated neurological disease are poorly understood. METHODS: BALB/c mice were intracerebrally injected with TBEV, followed by evaluation of chemokine and cytokine profiles using protein array analysis. The virus-infected mice were treated with the CC chemokine antagonist Met-RANTES or anti-RANTES mAb to determine the role of RANTES in affecting TBEV-induced neurological disease. The underlying signaling mechanisms were delineated using RANTES promoter luciferase reporter assay, siRNA-mediated knockdown, and pharmacological inhibitors in human brain-derived cell culture models. RESULTS: In a mouse model, pathological features including marked inflammatory cell infiltrates were observed in brain sections, which correlated with a robust up-regulation of RANTES within the brain but not in peripheral tissues and sera. Antagonizing RANTES within CNS extended the survival of mice and reduced accumulation of infiltrating cells in the brain after TBEV infection. Through in vitro studies, we show that virus infection up-regulated RANTES production at both mRNA and protein levels in human brain-derived cell lines and primary progenitor-derived astrocytes. Furthermore, IRF-3 pathway appeared to be essential for TBEV-induced RANTES production. Site mutation of an IRF-3-binding motif abrogated the RANTES promoter activity in virus-infected brain cells. Moreover, IRF-3 was activated upon TBEV infection as evidenced by phosphorylation of TBK1 and IRF-3, while blockade of IRF-3 activation drastically reduced virus-induced RANTES expression. CONCLUSIONS: Our findings together provide insights into the molecular mechanism underlying RANTES production induced by TBEV, highlighting its potential importance in the process of neuroinflammatory responses to TBEV infection

    Anti-noise-folding regularized subspace pursuit recovery algorithm for noisy sparse signals

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    © 2014 IEEE. Denoising recovery algorithms are very important for the development of compressed sensing (CS) theory and its applications. Considering the noise present in both the original sparse signal x and the compressive measurements y, we propose a novel denoising recovery algorithm, named Regularized Subspace Pursuit (RSP). Firstly, by introducing a data pre-processing operation, the proposed algorithm alleviates the noise-folding effect caused by the noise added to x. Then, the indices of the nonzero elements in x are identified by regularizing the chosen columns of the measurement matrix. Afterwards, the chosen indices are updated by retaining only the largest entries in the Minimum Mean Square Error (MMSE) estimated signal. Simulation results show that, compared with the traditional orthogonal matching pursuit (OMP) algorithm, the proposed RSP algorithm increases the successful recovery rate (and reduces the reconstruction error) by up to 50% and 86% (35% and 65%) in high noise level scenarios and inadequate measurements scenarios, respectively

    Analytical models for delay and power analysis of zero-V load unipolar thin-film Transistor Logic Circuits

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    In thin-film transistor (TFT) logic circuit applications, propagation delay and power dissipation are two key constraints to be considered in optimal circuit design and synthesis. The unipolar zero-V-load logic design is widely used for implementation of TFT digital circuits, because of the simple structure, easy processing, and relatively high gain. In this paper, the analytical models for delay and power were developed for zero-V-load inverters, which clarify the relationships between device and design parameters and the two key design constraints. The proposed models were verified by circuit simulations, and could serve as a guideline for optimal design of unipolar zero-V-load logic circuits

    Mixed adsorption and surface tension prediction of nonideal ternary surfactant systems

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    To deal with the mixed adsorption of nonideal ternary surfactant systems, the regular solution approximation for nonideal binary surfactant systems is extended and a pseudo-binary system treatment is also proposed. With both treatments, the compositions of the mixed monolayer and the solution concentrations required to produce given surface tensions can be predicted based only on the gamma-LogC curves of individual surfactants and the pair interaction parameters. Conversely, the surface tensions of solutions with different bulk compositions can be predicted by the surface tension equations for mixed surfactant systems. Two ternary systems: SDS/Hyamine 1622/AEO7, composed of homogeneous surfactants, and AES/DPCl/AEO9, composed of commercial surfactants, in the presence of excess NaCl, are examined for the applicability of the two treatments. The results show that, in general, the pseudo-binary system treatment gives better prediction than the extended regular solution approximation, and the applicability of the latter to typical anionic/cationic/nonionic nonideal ternary surfactant systems seems to depend on the combined interaction parameter, (βans+βcns)/2−βacs/4 {\mathop {(\beta }\nolimits_{an}^s } + {\mathop \beta \nolimits_{cn}^s })/2 - {\mathop \beta \nolimits_{ac}^s }/4 : the more it deviates from zero, the larger the prediction difference. If (βans+βcns)/2−βacs/4 {\mathop {(\beta }\nolimits_{an}^s } + {\mathop \beta \nolimits_{cn}^s })/2 - {\mathop \beta \nolimits_{ac}^s }/4 rarr0, good agreements between predicted and experimental results can be obtained and both treatments, though differently derived, are interrelated and tend to be equivalent

    Multipotent stem cells with neural crest stem cells characteristics exist in bovine adipose tissue

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    Neural crest stem cells (NCSCs) often referred to as the fourth germ layer, comprise a migratory, stem and progenitor cell population and are synonymous with vertebrate evolution and development. The cells follow specific paths to migrate to different locations of the body where they generate a diverse array of cell types and tissues. There are NCSCs which are maintained in an undifferentiated state throughout the life in the animal tissues. Based on some cells migratory property, we successfully developed a separation strategy to isolate and identify a population of adipose-derived stem cells with neural crest stem cell features in adult bovine adipose tissues within minimally-invasive surgical procedures. The cells have a high degree of multi-potency and self-renewal capabilities, can be cultured and maintained in feeder-free adhesion conditions as monolayer cells, and also be able to grow in the suspension condition in the form of neurosphere. For the purpose of simple description, we name this type cell as bovine adipose-derived neural crest stem cell (baNCSC). Taken together our study describes a readily accessible source of multipotent baNCSC for autologous tissue engineer and cell-based therapeutic researches

    Blockchain Based Secure Package Delivery via Ridesharing

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    © 2019 IEEE. Delivery service via ridesharing is a promising service to share travel costs and improve vehicle occupancy. Existing ridesharing systems require participating vehicles to periodically report individual private information (e.g., identity and location) to a central controller, which is a potential central point of failure, resulting in possible data leakage or tampering in case of controller break down or under attack. In this paper, we propose a Blockchain secured ridesharing delivery system, where the immutability and distributed architecture of the Blockchain can effectively prevent data tampering. However, such tamper-resistance property comes at the cost of a long confirmation delay caused by the consensus process. A Hash-oriented Practical Byzantine Fault Tolerance (PBFT) based consensus algorithm is proposed to improve the Blockchain efficiency and reduce the transaction confirmation delay from 10 minutes to 15 seconds. The Hash-oriented PBFT effectively avoids the double-spending attack and Sybil attack. Security analysis and simulation results demonstrate that the proposed Blockchain secured ridesharing delivery system offers strong security guarantees and satisfies the quality of delivery service in terms of confirmation delay and transaction throughput
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