104 research outputs found

    New standards of Bituminous mixtures and cement concrete

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    In the thesis paper “New standards of Bituminous mixtures and cement concrete” I describe the ways of acquiring a certificate of production control and introducing the building product to the market in order to serve its purposes. To master the certificate acquirement, a wide range of expert knowledge is necessary, and further education is obligatory with its development. In this field of expertise more and more knowledge is expected not only from the experts, but also from other participants in the building process. In many cases some individuals outside the building industry also wish to acquire the basic information. The thesis paper features all of the phases of acquirement and sustenance of the certificate, beginning with knowledge on the basic materials, forming rules of procedure and the type- examination. It also features the introduction of a production control system, the initial inspection and the inspection according to the acquirement of a certificate of production control, providing a conformity declaration and CE information, as well as conformity control and the permanent external control, the knowledge on the technological procedures and all the parallel activities, for example testing of the products. A comparison between the new and the abolished standards has also been included

    Protitrombotično zdravljenje in njegove indikacije

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    Protitrombotično zdravljenje pri bolniku, ki prejema simptomatsko zdravljenje

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    Preprečevanje venske trombembolije pri bolnikih z rakom

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    Effectiveness and safety of anticoagulant versus antiplatelet therapy in patients after endovascular revascularisation of the lower limb

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    Background: After revascularisation, patients with peripheral arterial disease (PAD) are routinely prescribed antiplatelet treatment (APT). Patients who receive anticoagulant treatment (ACT) due to comorbidity are an exception. We set out to determine possible differences in the effectiveness and safety between ACT and APT in patients after endovascular revascularisation of the lower limb arteries. Methods: In a single-centre retrospective cohort study, we analysed the data of 1,587 PAD patients who underwent successful endovascular revascularisation of the lower limb arteries due to disabling intermittent claudication or chronic critical limb ischemia over a 5-year period. Patients were divided into the ACT and APT groups based on their prescribed treatment. After balancing both groups’ baseline characteristics with propensity score matching, we compared the effectiveness and safety of both treatment regimens in the first year after revascularisation. Results: Compared to patients with APT, patients with ACT were older, and more often reported arterial hypertension, diabetes, chronic kidney disease, congestive heart failure, ischaemic heart disease, and prior stroke or transient ischaemic attack. After matching, the odds ratio (OR) for an effective outcome with ACT versus APT was 0.78 (95% CI 0.39–1.59; p=0.502), while the OR for a safe outcome with ACT versus APT was 4.12 (95% CI 0.82–20.73; p=0.085). Conclusions: Patients who required ACT were elderly, had more cardiovascular risk factors and had more advanced PAD than patients with APT. After matching, we found no statistically significant difference in the effectiveness and safety of both treatment regimens; however the wide OR confidence intervals warrant further research
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