Porch Culture: The Stoop of Entitlement

To the class of 2017: Welcome to Gettysburg. Welcome to the next four years of your life. Welcome to the school where you spend vast amounts of time at or trying to get into a Fraternity House. Welcome to the school plagued by porch culture. [excerpt

Chains

Chains is a poem that was inspired by the events surrounding the Steubenville Rape Case, and it is my interpretation of what the victim could have been feeling. The poem was written as a way for me to try to understand how something like this could have happened

Dandelion Game

Dandelion Game is a poem inspired by a picture of myself when I played T-ball at age 6 and would spend most of my time picking dandelions in the outfield

Effects of Community-Based Management on Amazon River Turtles: A Case Study of Podocnemis sextuberculata

Podocnemis sextuberculata is cited as "vulnerable" on the International Union for Conservation of Nature Red List due to a decline in its population as a result of the intensive exploitation pressure throughout its range. Understanding the effects of environmental characteristics and human activities on turtle populations is essential to improve current conservation programs. We analyzed the abundance of Podocnemis sextuberculata in the lower Amazon, where a management experiment is under way, by comparing neighboring areas with and without community-based management (CBM) initiatives. In addition, we analyzed the influence of environmental variables on the species' abundance. Abundance was measured by captures per unit effort expressed in number of individuals (CPUEN) and biomass (CPUEB). The effects of CBM and environmental variables were tested by General Linear Model analysis. A total of 354 individuals were captured, 321 in the areas under CBM and 33 in areas without CBM. CPUEN and CPUEB were strongly correlated, and their values were about 10-fold higher in the areas carrying out CBM initiatives. The variable that best explained variation in CPUEN and CPUEB was CBM. Distance between the sampling point and the nearest nesting beach and river level also influenced capture rates. Results clearly show that local fishing restrictions can have a positive influence on turtle populations. © 2013 Chelonian Research Foundation

Phenotypic expansion of CACNA1C-associated disorders to include isolated neurological manifestations

International audiencePurpose:CACNA1C encodes the alpha-1-subunit of a voltage-dependent L-type calcium channel expressed in human heart and brain. Heterozygous variants in CACNA1C have previously been reported in association with Timothy syndrome and long QT syndrome. Several case reports have suggested that CACNA1C variation may also be associated with a primarily neurological phenotype.Methods:We describe 25 individuals from 22 families with heterozygous variants in CACNA1C, who present with predominantly neurological manifestations.Results:Fourteen individuals have de novo, nontruncating variants and present variably with developmental delays, intellectual disability, autism, hypotonia, ataxia, and epilepsy. Functional studies of a subgroup of missense variants via patch clamp experiments demonstrated differential effects on channel function in vitro, including loss of function (p.Leu1408Val), neutral effect (p.Leu614Arg), and gain of function (p.Leu657Phe, p.Leu614Pro). The remaining 11 individuals from eight families have truncating variants in CACNA1C. The majority of these individuals have expressive language deficits, and half have autism.Conclusion:We expand the phenotype associated with CACNA1C variants to include neurodevelopmental abnormalities and epilepsy, in the absence of classic features of Timothy syndrome or long QT syndrome