551 research outputs found

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    Public and Private Sector HRD Differences

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    The purpose of this study is to examine literature on the differences between the public and private sector with respect to human resource development (HRD). This study will define HRD in addition to exploring various published theories on sector differences. The study will address the importance of values, in addition to, specific sector differences. This study will specifically explore any theoretical, human resource management (HRM), organizational development (OD), organizational commitment, wage or motivational differences between the public and private sector. This study is valuable because it will reveal and define some of the public and private sector differences with respect to human resources. This study, in part, helps to answer the question about what is HRD and how is it defined

    Aboriginal Australia and the new federalism initiative

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    Aboriginal land and development in the Northern Territory

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    Towards the public sector financing of Aboriginal self government

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    Cytotoxic polyfunctionality maturation of cytomegalovirus-pp65-specific CD4 + and CD8 + T-cell responses in older adults positively correlates with response size

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    Cytomegalovirus (CMV) infection is one of the most common persistent viral infections in humans worldwide and is epidemiologically associated with many adverse health consequences during aging. Previous studies yielded conflicting results regarding whether large, CMV-specific T-cell expansions maintain their function during human aging. In the current study, we examined the in vitro CMV-pp65-reactive T-cell response by comprehensively studying five effector functions (i.e., interleukin-2, tumor necrosis factor-α, interferon-γ, perforin, and CD107a expression) in 76 seropositive individuals aged 70 years or older. Two data-driven, polyfunctionality panels (IL-2-associated and cytotoxicity-associated) derived from effector function co-expression patterns were used to analyze the results. We found that, CMV-pp65-reactive CD8 + and CD4 + T cells contained similar polyfunctional subsets, and the level of polyfunctionality was related to the size of antigen-specific response. In both CD8 + and CD4 + cells, polyfunctional cells with high cytotoxic potential accounted for a larger proportion of the total response as the total response size increased. Notably, a higher serum CMV-IgG level was positively associated with a larger T-cell response size and a higher level of cytotoxic polyfunctionality. These findings indicate that CMV-pp65-specific CD4 + and CD8 + T cell undergo simultaneous cytotoxic polyfunctionality maturation during aging
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