Health Risk Perceptions Are Associated with Domestic Use of Basic Water and Sanitation Services—Evidence from Rural Ethiopia

We examine factors associated with the use of basic water supply and sanitation services as part of an integrated community-based nutrition programme which included a drinking water, sanitation and hygiene (WaSH) intervention and emphasise findings related to health risk perceptions. Data were collected from 2658 households in four regions in Ethiopia with a cross-sectional survey in WaSH intervention areas, as well as in control areas, where the intervention was not implemented. The data were analysed using bivariate and multivariable regression analysis. Awareness of health risk factors related to inadequate WaSH was high in the programme area. The use of basic water and sanitation services was associated with several health risk perceptions: Perceiving water quality as good increased the odds of using basic water services as opposed to believing the water quality was poor (OR 3.94; CI 3.06–5.08; p ≤ 0.001). Believing that drinking unsafe water was the main cause for diarrhoea increased the odds of using basic water services (OR 1.48; CI 1.20–1.81; p ≤ 0.001). In the WaSH intervention group, the use of basic sanitation was more likely than in the control group. The use of basic sanitation was associated with households who had previously received sanitation training, as opposed to such who had not (OR 1.55; CI 1.22–1.97; p ≤ 0.001). Perceiving dirty space as the main cause of diarrhoea (OR 1.81; CI 1.50–2.19; p ≤ 0.001), and privacy when using a latrine (OR 2.00; CI 1.67–2.40; p ≤ 0.001), were associated with higher odds of using basic sanitation. Households that indicated a disadvantage of owning a latrine was maintenance costs were less likely to use basic sanitation (OR 0.49; CI 0.38–0.63; p ≤ 0.001). Risk perceptions were important determinants of use of basic services. The findings point to risk perceptions motivating the application of positive WaSH-related and health-protective behaviours. This suggests that well-designed health risk communication strategies may be effective for engaging households in healthy WaSH behaviour

Budgeting for Environmental Health Services in Healthcare Facilities: A Ten-Step Model for Planning and Costing

Environmental health services (EHS) in healthcare facilities (HCFs) are critical for safe care provision, yet their availability in low- and middle-income countries is low. A poor understanding of costs hinders progress towards adequate provision. Methods are inconsistent and poorly documented in costing literature, suggesting opportunities to improve evidence. The goal of this research was to develop a model to guide budgeting for EHS in HCFs. Based on 47 studies selected through a systematic review, we identified discrete budgeting steps, developed codes to define each step, and ordered steps into a model. We identified good practices based on a review of additional selected guidelines for costing EHS and HCFs. Our model comprises ten steps in three phases: planning, data collection, and synthesis. Costing-stakeholders define the costing purpose, relevant EHS, and cost scope; assess the EHS delivery context; develop a costing plan; and identify data sources (planning). Stakeholders then execute their costing plan and evaluate the data quality (data collection). Finally, stakeholders calculate costs and disseminate findings (synthesis). We present three hypothetical costing examples and discuss good practices, including using costing frameworks, selecting appropriate indicators to measure the quantity and quality of EHS, and iterating planning and data collection to select appropriate costing approaches and identify data gaps

Environment and Obesity in the National Children\u27s Study

Objective: In this review we describe the approach taken by the National Children’s Study (NCS), a 21-year prospective study of 100,000 American children, to understanding the role of environmental factors in the development of obesity. Data sources and extraction: We review the literature with regard to the two core hypotheses in the NCS that relate to environmental origins of obesity and describe strategies that will be used to test each hypothesis. Data synthesis: Although it is clear that obesity in an individual results from an imbalance between energy intake and expenditure, control of the obesity epidemic will require understanding of factors in the modern built environment and chemical exposures that may have the capacity to disrupt the link between energy intake and expenditure. The NCS is the largest prospective birth cohort study ever undertaken in the United States that is explicitly designed to seek information on the environmental causes of pediatric disease. Conclusions: Through its embrace of the life-course approach to epidemiology, the NCS will be able to study the origins of obesity from preconception through late adolescence, including factors ranging from genetic inheritance to individual behaviors to the social, built, and natural environment and chemical exposures. It will have sufficient statistical power to examine interactions among these multiple influences, including gene–environment and gene–obesity interactions. A major secondary benefit will derive from the banking of specimens for future analysis

Timeline Follow-Back Versus Global Self-Reports of Tobacco Smoking: A Comparison of Findings With Non-Daily Smokers

Methods assessing non-daily smoking are of concern because biochemical measures can not verify self-reports beyond 7 days. This study compares two self-reported smoking measures for non-daily smokers. A total of 389 college students, (48% female, 96% white, mean age of 19) smoking between 1 and 29 days out of the past 30, completed computer assessments in three cohorts with the order of administration of the measures counterbalanced. Values from the two measures were highly correlated. Comparisons of Timeline Follow-Back (TLFB) with the global questions for the total sample of non-daily smokers yielded statistically significant differences (p\u3c.001), albeit small, between measures with the TLFB resulting on average in 2.38 more total cigarettes smoked out of the past 30 days, 0.46 less smoking days, and 0.21 more cigarettes smoked per day. Analyses by level of smoking showed that the discordance between the measures differed by frequency of smoking. Global questions of days smoked resulted in frequent reporting in multiples of five days, suggesting digit bias. Overall the two measures of smoking were highly correlated and equally effective for identifying any smoking in a 30-day period among non-daily smokers

Evaluating Mobile Survey Tools (MSTs) for Field-Level Monitoring and Data Collection: Development of a Novel Evaluation Framework, and Application to MSTs for Rural Water and Sanitation Monitoring

Information and communications technologies (ICTs) such as mobile survey tools (MSTs) can facilitate field-level data collection to drive improvements in national and international development programs. MSTs allow users to gather and transmit field data in real time, standardize data storage and management, automate routine analyses, and visualize data. Dozens of diverse MST options are available, and users may struggle to select suitable options. We developed a systematic MST Evaluation Framework (EF), based on International Organization for Standardization/International Electrotechnical Commission (ISO/IEC) software quality modeling standards, to objectively assess MSTs and assist program implementers in identifying suitable MST options. The EF is applicable to MSTs for a broad variety of applications. We also conducted an MST user survey to elucidate needs and priorities of current MST users. Finally, the EF was used to assess seven MSTs currently used for water and sanitation monitoring, as a validation exercise. The results suggest that the EF is a promising method for evaluating MSTs

Age and structure of the Shyok Suture in the Ladakh region of Northwestern India: Implications for slip on the Karakoram Fault System

A precise age for the collision of the Kohistan-Ladakh block with Eurasia along the Shyok suture zone (SSZ) is one key to understanding the accretionary history of Tibet and the tectonics of Eurasia during the India-Eurasia collision. Knowing the age of the SSZ also allows the suture to be used as a piercing line for calculating total offset along the Karakoram Fault, which effectively represents the SE border of the Tibetan Plateau and has played a major role in plateau evolution. We present a combined structural, geochemical, and geochronologic study of the SSZ as it is exposed in the Nubra region of India to test two competing hypotheses: that the SSZ is of Late Cretaceous or, alternatively, of Eocene age. Coarse-continental strata of the Saltoro Molasse, mapped in this area, contain detrital zircon populations suggestive of derivation from Eurasia despite the fact that the molasse itself is deposited unconformably onto Kohistan-Ladakh rocks, indicating that the molasse is postcollisional. The youngest population of detrital zircons in these rocks (approximately 92 Ma) and a U/Pb zircon date for a dike that cuts basal molasse outcrops (approximately 85 Ma) imply that deposition of the succession began in the Late Cretaceous. This establishes a minimum age for the SSZ and rules out the possibility of an Eocene collision between Kohistan-Ladakh and Eurasia. Our results support correlation of the SSZ with the Bangong suture zone in Tibet, which implies a total offset across the Karakoram Fault of approximately 130–190 km

The immune cell infiltrate populating meningiomas is composed of mature, antigen-experienced T and B cells

BACKGROUND: Meningiomas often harbor an immune cell infiltrate that can include substantial numbers of T and B cells. However, their phenotype and characteristics remain undefined. To gain a deeper understanding of the T and B cell repertoire in this tumor, we characterized the immune infiltrate of 28 resected meningiomas representing all grades. METHODS: Immunohistochemistry was used to grossly characterize and enumerate infiltrating lymphocytes. A molecular analysis of the immunoglobulin variable region of tumor-infiltrating B cells was used to characterize their antigen experience. Flow cytometry of fresh tissue homogenate and paired peripheral blood lymphocytes was used to identify T cell phenotypes and characterize the T cell repertoire. RESULTS: A conspicuous B and T cell infiltrate, primarily clustered in perivascular spaces, was present in the microenvironment of most tumors examined. Characterization of 294 tumor-infiltrating B cells revealed clear evidence of antigen experience, in that the cardinal features of an antigen-driven B cell response were present. Meningiomas harbored populations of antigen-experienced CD4+ and CD8+ memory/effector T cells, regulatory T cells, and T cells expressing the immune checkpoint molecules PD-1 and Tim-3, indicative of exhaustion. All of these phenotypes were considerably enriched relative to their frequency in the circulation. The T cell repertoire in the tumor microenvironment included populations that were not reflected in paired peripheral blood. CONCLUSION: The tumor microenvironment of meningiomas often includes postgerminal center B cell populations. These tumors invariably include a selected, antigen-experienced, effector T cell population enriched by those that express markers of an exhausted phenotype

Youth Practitioners Can Counter Fascism: What We Know and What We Need

Fascist, White nationalist, and misogynist groups are actively recruiting adolescent followers both online and in person. Youth development practitioners can play an important role in mitigating the influence of fascist ideologies on young people’s behavior and reducing the proliferation of youth-perpetrated harassment and violence. In this paper, we present a theoretical integration that draws on empirical research from multiple disciplines and youth development best practices to examine how youth practitioners can counter fascist recruitment of youth. There is much that youth development researchers and practitioners already know and do, or have the capacity to learn and do, that can mitigate the threat of fascist recruitment and deter young people from developmental trajectories leading them towards harmful ideologies and actions. In order to support youth development practitioners in effectively embodying this potential, we detail 3 sets of activities: (a) immunizing youth to reduce susceptibility to fascist recruitment, (b) intervening in fascist recruitment of specific youth, and (c) counter-recruiting youth into community organizing for social justice. For each set of activities, we describe the goals of each component, propose concrete actions it may entail, and highlight existing research and best practices in the field that can be applied to this current challenge. We then propose next steps in research–practice integration to further improve relevant strategies and point to existing resources for supporting youth in resisting fascist recruitment

Co-creating sustainability and responsibility: Exploring students perceptions of the classroom / workplace relationship

A growing population consumes an average of ‘1.7 earths' each year (CRM 2010) and is expected to reach nine-billion by 2050 (Young and Ernst 2012). 93% of CEOs view sustainability as a business issue (KPMG 2018), with 53% expecting to increase spending in this area. From an academic perspective, publications increasingly focus on sustainability and responsibility (herein S&R) (Handy 2012). In this context, Higher Education ‘can serve as a model of sustainability by integrating all aspects of campus life‘ (Cortese 2003). In this context, millennials increasingly wish to work for organizations who take sustainability seriously and ‘stand ready to take action’ (Cone 2019). Scholars emphasise the value of fundamental change in how decisions around problems associated with sustainability are addressed in knowledge systems (Bennett and Kane 2014; Ferri-Reed 2014). Our Business Studies degree students engage in co-creation, deliberatively working with students to deepen pedagogical understanding and create practical outcomes (Wyborn et al. 2019). Specifically, to facilitate transformative change through knowledge production (Trencher et al. 2014). To this end we seek to understand how aspects of the course can be further developed to enhance education, employability and the replication of co-produced knowledge. We elicit how elements of a Business Studies Course concerned with S&R support employability and consider how we modules can be adapted to further this agenda (i.e. Robertson and Duffy 2020). This responds to the shifting expectation of students, as future business leaders and managers with the potential to shape the orientation of business to S&R. Presenting with two or more students we demonstrate the application of co-creation in module development. Attendees will benefit from attendance by better understanding the learner perspective for S&R education, add value in curricula development and replicate co-creative practice in their own contexts