THE INFORMATION AND COMMUNICATION TECHNOLOGY – IMPACT ON THE HOSPITALITY INDUSTRY IN ROMANIA

In the context of an increasingly dynamic society, globalization has become one of the key issues, causing important changes in the evolution of all economic sectors and especially in the development of the tourism industry, an industry that depends heavily on the free movement of people and unhindered access to information. Although the implications of the globalization phenomenon on tourism are extremely diverse and profound, sometimes difficult to commensurate, the evolution of the information and communication technology is currently outlining the main directions of the global economy through the accelerated pace of innovation. The hospitality industry requires a high level of adaptability to the demands of the tourist market, and the information and communication technology represents an efficient tool for increasing the degree of correlation between tourist supply and clients' demands, thus turning into a real progress bond. Improving the efficiency of this sector's activity becomes one of the primary issues on an increasingly dynamic global market, the changes regarding the distribution channel, the marketing services and the customer relationship management representing the key elements in this respect. In this context, the hotel market in Romania acquires new dimensions, its performance depending on the strong influence that the implementation of the newest informational technologies has on it, determining important changes at both the management and the operational level

HEAT WAVES. CONCEPT, DEFINITION AND METHODS USED TO DETECT

Heat waves. Concepts, definition and methods used to detect. Heat waves have been assessed, as the most dangerous weather events in the United States and in Australia, due to its major impact on human body. Consequently, detailed analyses is needed, both at global as well as at regional or local scales. Due to the high number of definitions and methods used to detect heat waves in the international scientific literature, in this study, we propose a review of the concept, the methods and data used to detect. We also made a brief comparison between two methods: 95th percentile-based method and 35ºC fixed threshold method. As main result, we found that the 95th percentile method is more appropriate as it allows detection of the heat waves all around the year and for each weather stations under study, while the fixed threshold method is very sensitive to location of the weather stations and season

Regional Differentiations for the Temporal Variations of Atmospheric Precipitations in the Transylvanian Depression

This study refers to the trends in precipitation amounts in the central part of Romania (the Transylvanian Depression) between 1961-2000. The general trend was calculated using the least-squares linear fitting for the whole period and for every decade of the period: 1961-1970, 1971-1980, 1981-1990, 1991-2000. The main results of our research are: during the whole period there is a general decreasing trend in this region, especially in its southern area; during the first two decades, there was an increase trend, between 1981-1990 the general trend was a decrease and the trend for the last decade of the 20th century was variable

Future changes in extreme temperature indices in Cluj-Napoca, Romania

At present, research in climatology is mainly focusing on climate change and especially on global warming. Since climate change is already affecting large areas worldwide, it is important to study in details these changes at regional and local scale and to reduce its negative impact. The aim of this study is to analyze changes on extreme temperature indices over the periods 2041-2070 and 2071-2100 in Cluj-Napoca city using a set of 21 indices recommended by Expert Team for Climate Change Detection Monitoring and Indices. Extreme temperature indices for observed and modeled data were calculated by employing ClimPACT2 software. Modeled data for daily minimum and maximum temperature was extracted from EURO-CORDEX Project database. RCP4.5 and RCP8.5 scenarios of three regional climate models (RACMO22E, RCA4, and WRF331F) were considered. Next we compared the average values of the historical period (1981-2010) with the 2041-2070 and 2071-2100 periods for each scenario (RCP 4.5 and RCP 8.5) in order to obtain the future changes. The result of this study shows major changes for all the analyzed indices. The period 2071-2100 presents the highest changes under both analyzed scenarios

Cancer epidemiology in Central and South Eastern European countries

Aim To collect cancer epidemiology data in South Eastern European countries as a basis for potential comparison of their performance in cancer care. Methods The South Eastern European Research Oncology Group (SEEROG) collected and analyzed epidemiological data on incidence and mortality that reflect cancer management in 8 countries – Croatia, Czech Republic, Hungary, Romania, Poland, Slovakia, and Serbia and Montenegro in the last 20-40 years. Results The most common cancer type in men in all countries was lung cancer, followed by colorectal and prostate cancer, with the exception of the Czech Republic, where prostate cancer and colorectal cancer were more common. The most frequent cancer in women was breast cancer followed by colorectal cancer, with the exceptions of Romania and Central Serbia where cervical cancer was the second most common. Cancer mortality data from the last 20-40 years revealed two different patterns in men. In Romania and in Serbia and Montenegro, there was a trend toward an increase, while in the other countries mortality was declining, after increasing for a number of years. In women, a steady decline was observed over many years in the Czech Republic, Hungary, and Slovakia, while in the other countries it remained unchanged. Conclusions There are striking variations in the risk of different cancers by geographic area. Most of the international variation is due to exposure to known or suspected risk factors which provides a clear challenge to prevention. There are some differences in incidence and mortality that cannot be explained by exposure to known risk factors or treatment availabilities

Pharmacogenomic analyses of sunitinib in patients with pancreatic neuroendocrine tumors.

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Hydroxyapatite-ciprofloxacin delivery system: Synthesis, characterisation and antibacterial activity

The main objective of this study was to synthesize hydroxyapatite-ciprofloxacin composites using a chemical precipitation method and to evaluate the properties and in vitro release profile of the drug from the hydroxyapatite-ciprofloxacin composites. Composite characterization was achieved by FT-IR, XRD and DLS. Ciprofloxacin determination was accomplished by HPLC, resulting in good incorporation efficiency of the drug (18.13 %). The in vitro release study (Higuchi model C = K t1/2 and Ritger-Peppas model, C = K t0.6) showed a diffusion-controlled mechanism. The antibacterial activity showed that the bacterial growth inhibition zones were approximately equal for the synthesis composites and for the mechanical mixture on the Staphylococcus aureus germ. The use of hydroxyapatite, which is a biocompatible, bioactive and osteoconductive material, with ciprofloxacin, which has good antibacterial activity in this composite, makes it suitable for the development of bone grafts. Furthermore, the synthesis process allows a slow local release of the drug