29 research outputs found
Estimating the net return of a remote calving alarm system in a dairy farm
The aim of the study was to evaluate the net return of the implementation of a remote calving monitoring system for obstetrical and neonatal assistance on the herd economy in a dairy farm model. A total of 680 parturitions over a 7-yr period were evaluated. Age at first calving was restricted from 23 to 27 mo for primiparous cows to be included. Among groups of cows that were ready to calve in a 15-d interval, primiparous and multiparous were randomly assigned to the experimental group and monitored through a calving alarm system, whereas the others accounted for controls. Final parturition groups were as follows: control primiparous (CPP, n = 218), control multiparous (CM, n = 345), monitored primiparous (MPP, n = 56), and monitored multiparous (MM, n = 61). Monitored groups received prompt calving assistance and first neonatal care, whereas the presence of farm personnel was discontinuous for controls. A biological model was built considering significant differences in calf loss, early culling, milk production, and days open between groups. Then, a partial budget model was used to estimate costs and net return on a simulated herd of 100 lactating cows. Incidence of calf death was greater in control groups (11.06% and 10.73% in CPP and CM, respectively) compared with monitored cows (0.00% and 1.69% in MPP and MM, respectively). Multiparous cows with calf loss had increased relative risk (relative risk = 3.487) for early culling compared with multiparous counterparts with no neonatal loss. Daily milk production in the first 2 mo was 3.79 kg greater in multiparous cows with no dead calf, compared with their counterparts. A significant difference in median days open was found in MPP and CPP (118 and 148 d, respectively). In the final economic model, different simulations were analyzed. They were created assuming different prices or hypothesizing calving monitoring only in primiparous animals. The model estimated different, but always positive, net return. In conclusion, implementing a calving alarm system led to a net return from \u20ac37 to 90 per cow per year (\u20ac1 = US$1.15 at the time of the study). However, the device alone is not sufficient: it must be supported by qualified calving monitoring and assistance. Optimized personnel presence in the calving area at the right time leads to prompt calving and neonatal calf assistance and colostrum feeding within the first hours of life, thus reducing calf death and days open, and increasing milk production
Laparotomic intrauterine insemination with frozen-thawed semen in Sopravissana breed ewes in Central Italy
Intrauterine laparoscopic insemination is diffuse in sheep breeding, yet requires veterinary expertise and expensive equipment. Our aim was to evaluate the time required, reproductive outcome and post-operative complications of mini invasive laparotomic intrauterine insemination, as an alternative approach to laparoscopy. A total of 115 Sopravvissana breed ewes were enrolled, including 75 adults and 40 lamb ewes, after oestrus synchronisation. Ewes were sedated and restrained in dorsal recumbence. Uterine horns were exposed through an abdominal incision of 4\u20137 cm, cranially to the udder. Thawed semen, containing 100
7 106 progressive motile (70%) and morphologically normal (80%) sperm cells, was inoculated into uterine lumen through an intravenous catheter. The abdominal incision was then routinely closed. The time interval for: (a) laparotomy and uterine exteriorisation, (b) intrauterine insemination, (c) abdominal wall closure and (d) total procedure was recorded. Pregnancy, lambing, twinning rates and sex ratio were submitted to chi-square test, comparing lamb and adult ewes. Time intervals and the duration of laparotomic procedure were compared in lamb and adults through Mann\u2013Whitney U test for independent samples. Median \ub1 standard error (SE) of total time for laparotomic intrauterine insemination was 5.53 \ub1 0.07 and 4.99 \ub1 0.11 min, for adult and lamb ewes (p<.05), which was similar to what was reported for laparoscopic methods. At pregnancy check, 60% and 70% of adult and lamb ewes resulted pregnant. Laparotomy is poorly applied due to risk of adherence and decreased fertility. In our study, ewes were naturally bred in the following season with 90% pregnancy rate. Our results showed that time for laparotomy is quite similar to laparoscopic insemination, as for the conception and lambing rates.HIGHLIGHTS Time required for the overall procedure (5.53 \ub1 0.07 and 4.99 \ub1 0.11 min, for adult and lamb ewes, respectively, with significant difference (p<.05)) was similar to laparoscopic artificial insemination. About 60% and 70% of adult and lamb ewes resulted pregnant, respectively. No decreased fertility was observed in the following breeding season (90% pregnancy rate at natural insemination). Laparotomic approach is quite similar to laparoscopic insemination, in terms of time required for its complete achievement, for the conception and lambing rates; furthermore it has the advantage of reducing equipment costs
Environmental Factors Affecting the Reproductive Efficiency of Italian Simmental Young Bulls
The objectives of the study aimed to evaluate the effect of weather conditions and scrotal circumference (SC) on standard semen characteristics of Italian Simmental young bulls (n = 577), all raised in the same performance station and sampled by the artificial vagina (AV) method. Considering the increasing SC, the results showed a significant increase in quantitative semen parameters (p < 0.05 and p < 0.0001, for sperm concentration and total number of spermatozoa, respectively); for every extra centimeter of SC, 17.5 × 106 spermatozoa/mL and 0.102 × 109 of total spermatozoa were produced. The age of the animal at semen collection (395 and 465 days) had similar positive effects. The effect of the average temperature humidity index (THI limits ≤ 40 and ≥70) in the previous 60, 30, and 10 days before the semen collection was also considered. Sixty days before the semen collection, the increasing THI increased both primary (p < 0.0001) and secondary (p < 0.0001) abnormalities while the percentage of morphologically normal spermatozoa decreased (p < 0.0001). Thirty and ten days before collection, the same effect on morphological traits was maintained, but total and progressive motility was also influenced (p < 0.01) with an unexpected increasing pattern. Thus, environmental conditions can influence semen quality during the entire spermatogenesis and results can guide future research on this breed
Different expression of Defensin-B gene in the endometrium of mares of different age during the breeding season
Clues to the Formation of Liller 1 from Modeling Its Complex Star Formation History
Liller 1 and Terzan 5 are two massive systems in the Milky Way bulge hosting populations characterized by significantly different ages (Δt > 7-8 Gyr) and metallicities (Δ[Fe/H] ∼ 1 dex). Their origin is still strongly debated in the literature and all formation scenarios proposed so far require some level of fine-tuning. The detailed star formation histories of these systems may represent an important piece of information to assess their origin. Here we present the first attempt to perform such an analysis for Liller 1. The first key result we find is that Liller 1 has been forming stars over its entire lifetime. More specifically, three broad star formation episodes are clearly detected: (1) a dominant one, occurring some 12-13 Gyr ago with a tail extending for up to ∼3 Gyr; (2) an intermediate burst, between 6 and 9 Gyr ago; and (3) a recent one, occurring between 1 and 3 Gyr ago. The old population contributes to about 70% of the total stellar mass, and the remaining fraction is almost equally split between the intermediate and young populations. If we take these results at face value, they would suggest that this system unlikely formed through the merger between an old globular cluster and a giant molecular cloud, as recently proposed. On the contrary, our findings provide further support to the idea that Liller 1 is the surviving relic of a massive primordial structure that contributed to the Galactic bulge formation, similarly to the giant clumps observed in star-forming high-redshift galaxies
Common genetic variants on chromosome 9p21 are associated with myocardial infarction and type 2 diabetes in an Italian population
<p>Abstract</p> <p>Background</p> <p>A genomic region on chromosome 9p21 has been identified as closely associated with increased susceptibility to coronary artery disease (CAD) and to type 2 diabetes (T2D) although the evidence suggests that the genetic variants within chromosome 9p21 that contribute to CAD are different from those that contribute to T2D.</p> <p>We carried out an association case-control study in an Italian population to test the association between two single nucleotide polymorphisms (SNPs) on the 9p21 locus, rs2891168 and rs10811661, previously reported by the PROCARDIS study, and respectively myocardial infarction (MI) and T2D. Our aim was to confirm the previous findings on a larger sample and to verify the independence of their susceptibility effects: rs2891168 associated with MI but not with T2D and rs10811661 associated with T2D but not with MI.</p> <p>Methods</p> <p>Genomic DNA samples of 2407 Italians with T2D (602 patients), who had had a recent MI (600), or had both diseases (600) and healthy controls (605) were genotyped for the two SNPs. The genotypes were determined by allelic discrimination using a fluorescent-based TaqMan assay.</p> <p>Results</p> <p>SNP rs2891168 was associated with MI, but not with T2D and the G-allele odds ratio (OR) was 1.20 (95% CI 1.02-1.41); SNP rs10811661 was associated with T2D, but not with MI, and the T-allele OR was 1.27 (95% CI 1.04-1.55). ORs estimates from the present study and the PROCARDIS study were pooled and confirmed the previous findings, with greater precision.</p> <p>Conclusions</p> <p>Our replication study showed that rs2891168 and rs10811661 are independently associated respectively with MI and T2D in an Italian population. Pooling our results with those reported by the PROCARDIS group, we also obtained a significant result of association with diabetes for rs10811661 in the European population.</p
Gross-total resection of temporal low grade gliomas is a critically important factor in achieving seizure-freedom
Assessment of sensitivity and profitability of an intravaginal sensor for remote calving prediction in dairy cattle
One critical point of dairy farm management is calving and neonatal first care. Timely calving assistance is associated with the reduction of calf mortality and postpartum uterine disease, and with improved fertility in dairy cattle. This study aimed to evaluate the performance and profitability of an intravaginal sensor for the prediction of stage II of labor in dairy farms, thus allowing proper calving assistance. Seventy-three late-gestating Italian Holstein cows were submitted to the insertion of an intravaginal device, equipped with light and temperature sensors, connected with a Central Unit for the commutation of a radio-signal into a cell phone alert. The remote calving alarm correctly identified the beginning of the expulsive phase of labor in 86.3% of the monitored cows. The mean interval from alarm to complete expulsion of the fetus was 71.56 ± 52.98 min, with a greater range in cows with dystocia (p = 0.012). The sensor worked correctly in both cold and warm weather conditions, and during day-or night-time. The intravaginal probe was well tolerated, as any cow showed lesions to the vaginal mucosa after calving. Using sex-sorted semen in heifers and beef bull semen in cows at their last lactation, the economic estimation performed through PrecisionTree™ software led to an income improvement of 119 € and 123 €/monitored delivery in primiparous and pluriparous cows, respectively. Remote calving alarm devices are key components of “precision farming” management and proven to improve animal welfare, to reduce calf losses and to increase farm incomes
How to Predict Parturition in Cattle? A Literature Review of Automatic Devices and Technologies for Remote Monitoring and Calving Prediction
Cattle farming is facing an increase in number of animals that farmers must care for, to-gether with decreasing time for observation of the single animal. Remote monitoring systems are needed in order to optimize workload and animal welfare. Where the presence of personnel is constant, for example in dairy farms with great number of lactating cows or with three milk-ing/day, calving monitoring systems which send alerts during the prodromal stage of labor (stage I) could be beneficial. On the contrary, where the presence of farm personnel is not guaranteed, for example in smaller farms, systems which alert at the beginning of labor (stage II) could be pre-ferred. In this case, time spent observing periparturient animals is reduced. The reliability of each calving alarm should also be considered: automatic sensors for body temperature and activity are characterized by a time interval of 6–12 hours between the alarm and calving. Promising results have been shown by devices which could be placed within the vaginal canal, thus identifying the beginning of fetal expulsion and optimizing the timing of calving assistance. However, some cases of non-optimal local tolerability and cow welfare issues are reported. Future research should be aimed to improve Sensitivity (Se), Specificity (Sp) and Positive Predictive Value (PPV) of calving alert devices in order to decrease the number of false positive alarms and focusing on easy-to-apply, re-usable and well tolerated products