52 research outputs found

    COVID-19 Vaccination in Pregnancy, Paediatrics, Immunocompromised Patients, and Persons with History of Allergy or Prior SARS-CoV-2 Infection: Overview of Current Recommendations and Pre- and Post-Marketing Evidence for Vaccine Efficacy and Safety

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    VIII Encuentro de Docentes e Investigadores en Historia del Diseño, la Arquitectura y la Ciudad

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    Acta de congresoLa conmemoración de los cien años de la Reforma Universitaria de 1918 se presentó como una ocasión propicia para debatir el rol de la historia, la teoría y la crítica en la formación y en la práctica profesional de diseñadores, arquitectos y urbanistas. En ese marco el VIII Encuentro de Docentes e Investigadores en Historia del Diseño, la Arquitectura y la Ciudad constituyó un espacio de intercambio y reflexión cuya realización ha sido posible gracias a la colaboración entre Facultades de Arquitectura, Urbanismo y Diseño de la Universidad Nacional y la Facultad de Arquitectura de la Universidad Católica de Córdoba, contando además con la activa participación de mayoría de las Facultades, Centros e Institutos de Historia de la Arquitectura del país y la región. Orientado en su convocatoria tanto a docentes como a estudiantes de Arquitectura y Diseño Industrial de todos los niveles de la FAUD-UNC promovió el debate de ideas a partir de experiencias concretas en instancias tales como mesas temáticas de carácter interdisciplinario, que adoptaron la modalidad de presentación de ponencias, entre otras actividades. En el ámbito de VIII Encuentro, desarrollado en la sede Ciudad Universitaria de Córdoba, se desplegaron numerosas posiciones sobre la enseñanza, la investigación y la formación en historia, teoría y crítica del diseño, la arquitectura y la ciudad; sumándose el aporte realizado a través de sus respectivas conferencias de Ana Clarisa Agüero, Bibiana Cicutti, Fernando Aliata y Alberto Petrina. El conjunto de ponencias que se publican en este Repositorio de la UNC son el resultado de dos intensas jornadas de exposiciones, cuyos contenidos han posibilitado actualizar viejos dilemas y promover nuevos debates. El evento recibió el apoyo de las autoridades de la FAUD-UNC, en especial de la Secretaría de Investigación y de la Biblioteca de nuestra casa, como así también de la Facultad de Arquitectura de la UCC; va para todos ellos un especial agradecimiento

    Drug interactions in users of tablet vs. oral liquid levothyroxine formulations: a real-world evidence study in primary care

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    Several medications may interact with levothyroxine (LT4) intestinal absorption or metabolism, thus reducing its bioavailability. We investigated the variability of thyroid stimulating hormone (TSH) levels and prescribed daily dosages (PDDs) of LT4 before and during potential drug-drug interactions (DDIs) in users of tablets vs. oral liquid LT4 formulations

    Social Structure Analysis in Internet of Vehicles

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    International audienceInternet, in its most recent evolution, is going to be the playground where a multitude of heterogeneous interconnected " things " autonomously exchange information to accomplish some tasks or to provide a service. Recently, the idea of giving to those smart devices the capability to organize themselves according to a social structure, gave birth to the so-called paradigm of the Social Internet of Things. The expected benefits of SIoT range from the enhanced effectiveness, scalability and speed of the navigability of the network of interconnected objects, to the provision of a level of trustworthiness that can be established by averaging the social relationships among things that are " friends ". Bearing in mind the beneficial effects of social components in IoT, we consider a social structure in a vehicular context i.e., Social Internet of Vehicles (SIoV). In SIoV, smart vehicles build social relationships with other social objects they might come into contact, with the intent of creating an overlay social network to be exploited for information search and dissemination for vehicular applications. In this paper, we aim to investigate the social behavior of vehicles in SIoV and how it is affected by mobility patterns. Specifically, through the analysis of simulated traffic traces, we distinguish friendly and acquaintance vehicles based on the encounter time and connection maintenanc

    Regular use of acetaminophen or acetaminophen–codeine combinations and prescription of rescue therapy with non-steroidal anti-inflammatory drugs: a population-based study in primary care

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    Objective: There are contrasting positions concerning the benefit\u2013risk ratio of acetaminophen use for osteoarthritis (OA)-related pain. To clarify the effectiveness of acetaminophen or acetaminophen\u2013codeine combinations according to their regimen of use, we evaluated whether being a regular user (adherent) of these medications decreased the occurrence of rescue therapy with non-steroidal anti-inflammatory drugs (NSAIDs). Methods: Using the Health Search IMS Health Longitudinal Patient Database, we formed a cohort of patients aged 6518 years and newly treated with acetaminophen or acetaminophen\u2013codeine combinations for OA between 1 January 2001 and 31 December 2013. These patients were followed up for one year in which they were categorized as regular or irregular users of these medications according to a variable medication possession ratio (VMPR)\u2009 65\u200950% or lower. We operationally defined the rescue therapy as the use of any NSAIDs prescribed for OA-related pain. Results: Overall, 40,029 patients (69.5% females; mean age: 68\u2009\ub1\u200913.57) treated with acetaminophen or acetaminophen\u2013codeine combinations formed the cohort. After the first year of treatment, regular users showed a statistically significantly lower risk of being prescribed with rescue therapy with NSAIDs (OR\u2009=\u20090.89; 95% CI 0.84\u20130.96). Conclusion: These findings show that regular use of acetaminophen or acetaminophen\u2013codeine combinations may reduce the need for NSAIDs to treat OA-related pain

    Allopurinol adherence among patients with gout: an Italian general practice database study

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    Allopurinol is used as long-term therapy to reduce the occurrence of gout flares. This study estimated the impact of patient adherence to allopurinol on hyperuricaemia (serum uric acid levels, sUA > 6 mg/dl) and the identification of non-adherence predictors
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