Contemporary conservative treatment of priapism

Catedra Urologie şi Nefrologie Chirurgicală, USMF „N.Testemiţanu”, Secţia Urologie IMSP Spitalul Clinic Republican, Profilactoriul „Constructorul”, Secţia Urologie IMSP Spitalul Clinic Municipal „Sfînta Treime”, Al V-lea Congres de Urologie, Dializă şi Transplant Renal din Republica Moldova cu participare internaţională (1-13 iunie 2011)Summary. Eleven consecutive patients who presented with priapism were treated with 0,5 mg phenylephrine diluted in 2 ml normal saline injected directly into the corpus cavernosum. The aim of this study was to assess the effectiveness and complications of intracorporeal phenylephrine administration without aspiration or irrigation as a treatment for priapism. Blood pressure and pulse were measured before and after injection, and monitored every 15 minutes. If no detumescence was noted after 15 minutes, the injection was repeated. Neither penile blood aspiration, nor irrigation was performed. 9 of 11 responded with detumescence. The number of injections required ranged from 1 to 6. No changes in blood pressure, heart rate or side effects were observed. We believe that this is a safe and effective method for treatment of priapism. Routine initial aspiration or irrigation of the corpora before intracorporeal injection of adrenergic agents does not appear to be necessary

Contemporary treatment of metabolic and inflammatory diseases of kidney and urinary ways

Introduction. The problem of an adequate lavage of kidneys and urinary ways, regardless the new diuretic drugs that invaded the market, is still accute. A modern, effective drug shold have a detoxicating, antiseptic, spasmolytic, antyinflammatory, proteolytic action on the urinary tube formed of renal pelvis and calyces, ureter, bladder, and urethra. Objective. The present research has the objective to analyze the treatment results of two groups of patients with kidney and urinary ways inflammatory and metabolic diseases (I.M.D). Methods and Factual Material. A group of 22 patients with inflammatory and metabolic diseases underwent a classical treatment with anty-inflammatory, spasmolytic, detoxicating, etc. drugs and Nephroclins (drug produced by New Spirit Naturals Co., USA & Vitamax XXI century branch) twice a day for 30 days, and were compared with the control group of 30 patients who underwent the usual treatment only. All the patients were subject to monitoring of dysuria, pollakiuria, pain, feebleness, lack of appetite, and Jordano‘s sign before and after the treatment, as well as patients‘ subjective assessment of their own estate with number 1- as being fully comfortable and 5 - as feeling un comfortable and having numerous com plains. A comparative analyzis of the results of patients‘ tests from both groups, namely blood, urine, creatinine, bilirubin, alanine and asparagine transaminase examination, was undertaken. Then, kydneys‘ estate was studied using renography, chromocystoscopy, echography, and i.v urography. Patients from both groups underwent microbial adhesion test (MAT). Patients with no pyuria, hematuria, and epithelium that did not exceed the acceptable threshold followed De-Almeida test. Test results before and after drug taking were recorded using a previously drawn up form. Results. Comparative study of clinical signs monitoring and subjective estate of the patients in both groups, showed good efficacy all 22 patients from the basic group with inflammatory and metabolic diseases, including those with obstructive pyelonephritis and internal bladder obstruction. 8 patients from the control group had persisting urologic signs. Clinic and laboratory tests showed improval of clinical indexes in 20 out of 22 patients, and in 19 out of 30 patients in control group. The functional estate of kidneys has also improved in 17 out of 22 patients, and in 18 out of 30 patients respectively. It is interesting that microbialadhesion test was negativ in all patients from the first group and in 19 patients out 30 in the control group. No side effects in patients of the first group who took the drug were found. Conclusions. The comparative study that was carried out firstly, shows an important efficacy of Nephroclins in the treatment of inflammatory and metabolic diseases of the kidney and urinary ways. Secondly, the drug proves its efficacy both in patients with obstructive and non-obstructive diseases. And thirdly, none of the patients was victim of drug‘s side-effects

Сравнительная оценка структуры заболеваемости студентов I курса Государственного Медицинского и Фармацевтического Университета им. Н. A. Тестемицану

Department of Family Medicine and Laboratory of Genetics, Nicolae Testemiţanu State Medical and Pharmaceutical University, Chisinau, Republic of Moldova, Congresul III al Medicilor de Familie din Republica Moldova, 17–18 mai, 2012, Chişinău, Republica Moldova, Conferinţa Naţională „Maladii bronhoobstructive la copii”, consacrată profesorului universitar, doctor habilitat Victor Gheţeul, 27 aprilie, Chişinău, Republica MoldovaThe purpose of this work was to comparatively evaluate the morbidity spectrum of the first year students of the SMPhU ”Nicolae Testemiţanu” enrolled in 2002-2004 and 2010-2011. Materials and methods: the data of medical examination performed at the University Clinic of Primary Care were analyzed in order to estimate the morbidity spectra. Results: the comparative analysis of the health status of students revealed an increase of students being “sick” from 24.0% in 2002-2004 to 35.0% in 2010-2011. The comparative analysis of morbidity spectra denotes a significant increase in proportions of eye pathology, pathologies of urinary and digestive tracts and endocrine system in the morbidity structure during 2002-2011 period. Conclusions: our data support the need of medical examination of first-year students in order to identify the existing chronic pathologies, proper treatment, and monitoring their diseases during the academic years.Целью настоящей работы была сравнительная оценка структуры заболеваемости студентов первого курса Государственного Медицинского и Фармацевтического Университета имени „Николая Тестемицану”, поступивших на учебу в 2002-2004 и 2010-2011 годы. Материал и методы: результаты медицинского осмотра студентов первого курса 2002-2004 и 2010-2011 годов поступления, для определения спектра заболеваемости. Результаты: сравнительный анализ состояния здоровья студентов показал увеличение группы студентов «больных» от 24,0% в 2002-2004 гг. до 35,0% в 2010-2011 гг. В структуре заболеваемости за период 2002-2011 годы произошло значительное увеличение доли глазной патологии, патологии мочеполового, пищеварительного трактов и эндокринной системы. Выводы: Для выявления существующих хронических заболеваний, своевременного их лечения и мониторинга динамики состояния здоровья студентов во время учебы, необходимо проведение медицинского осмотра студентов на первом курсе

The estimation of the peculiarities and the activity degree of the consisting inflammatory processes in the benign prostatic hyperplasia

Secţia Urologie, IMSP Spitalul Clinic Municipal “ Sf. Treime”, Catedra Morfopatologie, USMF „N. Testemiţanu”, Secţia Ştiinţifică Morfopatologie, IMSP Institutul de Cercetări Ştiinţifice în Domeniul Ocrotirii Sănătăţii Mamei şi Copilului, Catedra Urologie şi Nefrologie Chirurgicală, USMF „N. Testemiţanu”, Al V-lea Congres de Urologie, Dializă şi Transplant Renal din Republica Moldova cu participare internaţională (1-13 iunie 2011)Summary. The conducted study has the aim to estimate the histopathological peculiarities of the inflammatory processes, evaluated in prostatic nodular hyperplasia, the character and the activity of these processes in the area of nodular hyperplasia structures, and the border limit in the adenectomy. The results of the morphopathological study allowed detailed diagnosis of the prostatic hyperplasia. Severe modifications of inflammatory origin and considerable implications of the structural-architectonical components indicate concomitant persisting or coexisting of chronic or acute prostatitis. The establishment of the lesion character, activity degree of the inflammatory process, saving border limit in the surgical management regarding the residual cavity of cleavage and postoperative prognosis was the second aim of the study. It facilitates the choice of the best therapeutic and surgical approach. The character of the inflammatory processes coexisting with prostatic benign hyperplasia was evaluated. A clinical-morphological concept of inflammatory associations in prostate benign hyperplasia was formulated

Characterization of the relations between morphology and physiological status of the pineal gland in connection with the somatic development level in turkeys reared in Romania

This research started from the premises of the existence of some possible relationships between indole and pineal peptide hormones and the somatic development, with participation of hypothalamic-pituitary complex. Experimental factors, which were the subject of the present paper, influenced the dynamics of corporal mass and fodder consumption, leading to the occurrence of some important structural modifications at the level of pineal gland. The exposure of the individuals to continuous light (photic pinealectomy) produces increases in corporal mass, showing the involvement of the pineal gland in neuro-endocrine-metabolic reactions, which contributes to the maintenance of homeostatic balance, including somatic ones. Biological material was represented by a number of 50 individuals belonging to B.U.T. Big 6 hybrid, reared on soil, on a permanent litter, which could assure the expanding of knowledge area regarding the relation between rearing technology, modulation of some microclimate parameters and growing performances. Were also realised cytometric and hystometric muscular determinations

Patogeneza proceselor inflamatorii în rinichi

Summary The aim of this study was to investigate the mechanisms of microbian inoculation and their influence on the inflammatory process development in the kidneys. The study was based on the group of pacients with the chronic pielonefritis, which were parallel with the routine investigation, examinated for the presence of the urinary reflux by the radioizotopic methods and the AFMF Introducere. Majoritatea infecţiilor urinare sunt localizate primar la nivelul intestinului uman, de unde acestea ajung în regiunea permeala la femei şi în regiunea meatului uretral la bărbaţi. Prin meatul uretral în ambele cazuri germenii vor accenziona contracurent cu ajutorul fimbriilor în uroteliul căilor urinare. Pe parcursul tubului urinar germenii se fixează pe celulele epiteliale are uroteliului, determinând apariţia sindromului inflamator. Prin secreţia unor lizine şi a unor endotoxine se realizează paralizia căilor urinare, ureterul transformându-se într-un tub rigid, ce permite ascensiunea germenilor patogeni până la bazinetul renal. Procesul de paralizie a musculaturii pieloureterale continuă, ceea ce contribuie la apariţia stazei, favorizând pătrunderea germenilor în interstiţiul renal. Obiective. Dezideratul acestei lucrări constă în determinarea rolului refluxului urinar şi a fenomenului adheziei microbiene în patogeneza inflamaţiilor renale. Material şi metodă. Studiul se bazează pe un grup de pacienţi cu pielonefrită cronică în număr de 18 persoane, cărora paralel cu investigaţiile de rutină l-i s-a determinat prezenţa refluxului urinar prin m etoda radioizotopică (renogramă sau scintigramă), precum şi prezenţa fenomenului adheziei fimbriale microbiene (FAFM) în sedimentul urinar. Rezultate. Prezenţa refluxului urinar determinat prin metoda radioizotopică a fost depistată la 15 pacienţi dintre cei 18 din lotul examinat. Schimbări ale sedimentului urinar, nu depistare a fenomenului adheziei fimbriale, au fost relevate la 14 pacienţi. Aşadar, se determină o corelaţie directă în ambele investigaţii efectuate. Mai frecvent fenomenul adheziei microbiene s-a depistat în sedimentul urinelor alkaline. Examenul bacteriologic al urinei examinate a depistat mai des geneza colibacilară şi pe cea proteică a infecţiei. Concluzie. Conform materialelor prezentate, în care la majoritatea pacienților s-a depistat refluxul urinar în asociere cu FAFM, putem presupune prezenţa ambelor mecanisme de inoculare microbiană în organ, care asociîndu-se duc la o progresare a procesului inflamator în rinichi

ON THE MECHANISM OF THE RELAXATION PULSE GLOW DISCHARGE

Abstract. A mechanism of the low pressure relaxation glow discharge pulse is presented. Theoretical predictions and experimentally obtained values of discharges parameters are compared. The ion mobility, the secondary electron emission, the ionisation and the electrical parameters have a strong influence on the characteristics while the diffusion is of lesser importance