59 research outputs found
Pharmaceuticals in sewage systems and surface waters – status quo
- Author
- Publication venue
- Essen : Emschergenossenschaft
- Publication date
- 01/01/2015
- Field of study
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Fish utilisation of managed realignments
- Author
- Boesch D.
- Bozeman E.L.
- Claridge P.N.
- Colclough S.R
- Colclough S.R.
- Copp G.H.
- Craft C.
- Craft C.
- Craft C.
- Crooks S.
- Dixon A.M.
- Hemingway K.
- Hettler W.F.
- Keer G.H.
- Kelley D.F.
- Klein R.J.T.
- Laffaille P.
- Leafe R.
- Lyndon A.R.
- Mathieson S.
- McIvor C.C.
- McLusky D.S.
- Peterson G. W.
- Rosas L.P.
- Rupp S.
- Shenker J.M.
- Simenstad C.A.
- Southward A.J.
- West J.M.
- Williams G.D.
- Publication venue
- 'Wiley'
- Publication date
- Field of study
Full text linkNew insights into the genetic etiology of Alzheimer's disease and related dementias
- Author
- Aaltonen L.
- Aaltonen V.
- Aarsland Dag
- Aavikko M.
- Abalos M.S.
- Abdelnour Carla
- Abner E.
- Abraham R.
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- Adams P.M.
- Adarmes-Gómez A.
- Adarmes-Gómez A.D.
- Aguilera N.
- Aguilera N.
- Aguirre A.
- Ahmad S.
- Akinyemi R.O.
- Al-Chalabi A.
- Alarcón-Martín Emilio
- Albert M.S.
- Albin R.L.
- Alcolea Daniel
- Alegret Montserrat
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- Allende I.R.
- Alonso M.D.
- Alonso M.D.
- Alvarez I.
- Alvarez L.
- Amer-Ferrer G.
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- Amouyel Philippe
- Anastasiou A.
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- Andrade V.
- Andreassen Ole A.
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- Antikainen R.
- Antonell A.
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- Aparicio H.J.
- Apostolova L.G.
- Appollonio I.
- Arcaro M.
- Archetti S.
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Get PDFCharacterization of the genetic landscape of Alzheimer's disease (AD) and related dementias (ADD) provides a unique opportunity for a better understanding of the associated pathophysiological processes. We performed a two-stage genome-wide association study totaling 111,326 clinically diagnosed/'proxy' AD cases and 677,663 controls. We found 75 risk loci, of which 42 were new at the time of analysis. Pathway enrichment analyses confirmed the involvement of amyloid/tau pathways and highlighted microglia implication. Gene prioritization in the new loci identified 31 genes that were suggestive of new genetically associated processes, including the tumor necrosis factor alpha pathway through the linear ubiquitin chain assembly complex. We also built a new genetic risk score associated with the risk of future AD/dementia or progression from mild cognitive impairment to AD/dementia. The improvement in prediction led to a 1.6- to 1.9-fold increase in AD risk from the lowest to the highest decile, in addition to effects of age and the APOE ε4 allele
Assessing the creativity of scientific explanations in elementary science: an insider–outsider view of intuitive assessment in the hypothesis space
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- Amabile T.M.
- Ausubel D.P.
- Balchin T.
- Berg R.
- Besemer S.P.
- Boden M.A.
- Boden M.A.
- Claxton G.
- Colman A.M.
- Craft A.
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- Csikszentmihalyi M.
- de la Harpe B.
- DES (Department for Education and Skills)
- DES (Department for Education and Skills)
- DfES (Department for Education and Skills)
- Douglas P. Newton
- Fox H.
- Gardner H.
- Gouge K.
- Jardine L.
- NACCCE (National Advisory Committee on Creative and Cultural Education)
- Newton D.P.
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- Petty G.
- Roberts S.
- Rogers M.
- Rose J.
- Sefton‐Green J.
- Siegel S.
- Treffinger D.
- Treffinger D.J.
- Williams F.E.
- Wolpert L.
- Publication venue
- 'Informa UK Limited'
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Full text linkAlterações metabólicas e funcionais do cobre em diabetes mellitus
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- ARAI K.
- BALEVSKA P.S.
- BENSON G.D.
- BODE A.M.
- BREMNER J.
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- BUCHMAN A.L.
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- CARLTON W.W.
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- FISCHER P.W.F.
- GALLAGER C.H.
- GILLERY P.
- GODIN D.V.
- GUGLIUCCI A.
- HAGGLOF B.
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- HASSEL C.A.
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- JAIN S.K.
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- KLEVAY L.M.
- LAU A.L.
- Lucia de Fátima Campos Pedrosa
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- MADIA A.M.
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- McARDLE H.J.
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- McDERMOTT B.M.
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- SJÖGREN A.
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- STRAIN J.J.
- Sílvia Maria Franciscato Cozzolino
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- THORNALLEY P.
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- TWARDOWSKA-SAUCHA K.
- VILTER R.W.
- WACHNIK A.
- WALTER R.M.
- WEINER A.L.
- WERMAN M.J.
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- WILLIAMS D.M.
- WILLIAMS N.R.
- YAZIGI A.
- Publication venue
- 'FapUNIFESP (SciELO)'
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Full text linkSome student teachers’ conceptions of creativity in school science
- Author
- Altshuller G.
- American Association for the Advancement of Science (AAAS)
- Barrow R.
- Beswick K.
- Bjerstedt A.
- Boden M.A.
- Boden M.A.
- Central Advisory Agency for England (CACE)
- Colman A.M.
- Craft A.
- Csikszentmihalyi M.
- D.P. Newton
- Davies D.
- de Bono E.
- Department for Education and Employment/Qualifications and Curriculum Authority (DfEE/QCA)
- Department for Education and Skills (DfES)
- Dewey J.
- Dickinson V.L.
- Edmonds J.
- Eysenck H.J.
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- Garner R.
- Howe A.
- Klahr D.
- Kwang N.A.
- L.D. Newton
- Mayer R.E.
- McPherson J.H.
- Milne I.
- National Advisory Committee on Creative and Cultural Education (NACCCE)
- Newton D.P.
- Office for Standards in Education (OfSTED)
- Osborn A.
- Ovens P.
- Qualifications and Curriculum Authority (QCA)
- Qualifications and Curriculum Authority/Department for Education and Employment (QCA/DfEE)
- Sternberg R.J.
- Sternberg R.J.
- Taylor R.
- Torrance E.P.
- Weisberg R.W.
- Publication venue
- 'Informa UK Limited'
- Publication date
- Field of study
Full text linkBorrelioses, agentes e vetores
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- Abel I.S.
- Aberer E.
- Ackermann R.
- Adivaldo H. Fonseca
- Afzelius A.
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- Barboza W.G.A.
- Barros P.J.L.
- Battaly G.R.
- Battesti D.M.
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- Sonenshine D.E.
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- Walker E.D.
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- Zaher
- Zbinden R.
- Zingg B.C.
- Zung J.L.
- Publication venue
- 'FapUNIFESP (SciELO)'
- Publication date
- Field of study
Full text linkThe effect of gonadal hormones on pain and nociception
- Publication venue
- Publication date
- 01/01/2005
- Field of study
No full textT'aint what you do (it's the way that you do it) : ICT and creativity in the primary school classroom
- Author
- Publication venue
- 'Springer Science and Business Media LLC'
- Publication date
- 01/01/2010
- Field of study
No full textThis paper reports on one strand of a PhD study that examines newly qualified teachers’ use of Information and Communications Technologies (ICT) to support teaching and learning in Scottish primary classrooms during the first two years of their career. Preliminary data analysis indicates that some of the new teachers are creative, innovative users of new technologies who have embedded ICT effectively into their classroom practice while others remain reluctant users. This paper looks at some of the factors that differentiate the creative from the reluctant. Three levels of influence are discussed, and the interactions between them. They are the national/authority level, the school level and the individual or personal level. Some necessary, although not in themselves sufficient, conditions for creative use of ICT are identified as well as some desirable ones
A Systematic Review for Effective Management of Central Venous Catheters and Catheter Sites in Acute Care Paediatric Patients
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- Publication venue
- 'Wiley'
- Publication date
- Field of study
No full text- …
