Implication of Adam Related Metalloproteases in Equine Laminitis

Master of Science (M.S.

Ending a NYSE tradition: The 1975 Unraveling of Broker\u27s fixed commissions and its Long term impact on Financial Advertising

On May 1, 1975 (“Mayday”), the New York Stock Exchange jettisoned its 183 year old tradition of fixed rate broker commissions in favor of competitive, negotiated rates. While many events, institutions, and individuals helped inspire this controversial policy change, this paper focuses on the pivotal role played by one Exchange insider, NYSE President Robert Haack. Despite his original stalwart defense of fixed rates, Haack came to support rate deregulation. Haack’s rationale for endorsing negotiated rates is evaluated as well as how the new commission fee structure led to surprising changes in the advertising landscape on Wall Street. This paper argues that Mayday transformed the securities industry in more ways than anyone had envisioned at the time

A Master Plan and Prototype Condominium for Taos Ski Valley

With the tremendous technological advances we have experienced in recent years, and shall continue to experience, one will find the working individual\u27s week shortened to thirty, even twenty, hours. Machines will be responsible for a vast amount of labor currently conducted by men. Accompanying this decrease in working hours will be a high correlation of leisure time, much of which will be spent in recreation. At present, facilities in all areas of recreation are highly limited. In the future, a large portion of man\u27s energy will be directed toward provision of adequate facilities in keeping with his role of leisure and toward directing his excess hours to a healthy outlet

Archaeological Investigations at the Fort Hill Earthwork Complex

Geophysical and archaeological investigations were conducted this past summer at the Fort Hill Earthwork Complex located in the Rocky River Reservation of the Cleveland Metroparks. Our investigations have not only revealed when the earthworks were created and by which prehistoric culture group, but we also have uncovered data to suggest how they were constructed and for what possible purpose they may have served. In addition, we conducted extensive archival research at several local historical societies and museums looking for previously unpublished information about this site’s initial discovery in the mid-1800s and for any additional information concerning the prehistoric occupation of the Rocky River Valley.https://engagedscholarship.csuohio.edu/u_poster_2018/1006/thumbnail.jp

Mechanisms of Zika virus infection and neuropathogenesis

A spotlight has been focused on the mosquito-borne Zika virus (ZIKV) because of its epidemic outbreak in Brazil and Latin America, as well as the severe neurological manifestations of microcephaly and Guillain–Barré syndrome associated with infection. In this review, we discuss the recent literature on ZIKV-host interactions, including new mechanistic insight concerning the basis of ZIKV-induced neuropathogenesis

Gonadal hormones, but not sex, affect the acquisition and maintenance of a Go/No-Go odor discrimination task in mice

In mice, olfaction is crucial for identifying social odors (pheromones) that signal the presence of suitable mates. We used a custom-built olfactometer and a thirst-motivated olfactory discrimination Go/No-Go (GNG) task to ask whether discrimination of volatile odors is sexually dimorphic and modulated in mice by adult sex hormones. Males and females gonadectomized prior to training failed to learn even the initial phase of the task, which involved nose poking at a port in one location obtaining water at an adjacent port. Gonadally intact males and females readily learned to seek water when male urine (S+) was present but not when female urine (S−) was present; they also learned the task when non-social odorants (amyl acetate, S+; peppermint, S−) were used. When mice were gonadectomized after training the ability of both sexes to discriminate urinary as well as non-social odors was reduced; however, after receiving testosterone propionate (castrated males) or estradiol benzoate (ovariectomized females), task performance was restored to pre-gonadectomy levels. There were no overall sex differences in performance across gonadal conditions in tests with either set of odors; however, ovariectomized females performed more poorly than castrated males in tests with non-social odors. Our results show that circulating sex hormones enable mice of both sexes to learn a GNG task and that gonadectomy reduces, while hormone replacement restores, their ability to discriminate between odors irrespective of the saliency of the odors used. Thus, gonadal hormones were essential for both learning and maintenance of task performance across sex and odor type.We thank David Giese for help in programming the apparatus used in GNG testing and Alberto Cruz-Martin for comments on an early version of the manuscript. This work was supported by NIDCD grant DC008962 to JAC. (DC008962 - NIDCD grant)Accepted manuscrip

Raising students’ ethical sensitivity with a value relevance approach

This paper introduces a new approach to raising students’ ethical sensitivity. This new “Value Relevance Approach” (VRA) employs active instructional techniques to demonstrate the costs (benefits) associated with acting in an unethical (ethical) manner. Using a within and between subjects, pre/post-test design, we (1) assess the effectiveness of the VRA in affecting students’ ethical sensitivity and (2) compare the effectiveness of the VRA in affecting students’ ethical sensitivity to that of a traditional learning approach (TLA). The results indicate that ethical sensitivity improves for subjects in the VRA condition and also improves to a greater extent than for subjects in the TLA condition, suggesting that the VRA is more effective than a TLA in promoting ethical sensitivity among students

Pedagogic Metaphors and the Nature of Accounting Signification

This paper concerns three metaphors for financial statements associated with accounting education: lenses, photographs, and the board game, Scrabble. These metaphors not only describe financial statements but also affect our interpretations of them and our behavior towards them. The lens metaphor has many implications that accounting cannot live up to; however, that does not mean that it is an inappropriate metaphor to express our aspirations for accounting and to inspire our students. The Scrabble metaphor is a somewhat pejorative metaphor that we may cynically apply to accounting, but it may also be an effective means of criticizing mindless manipulation of financial statement elements. The photographic metaphor, occupying a middle ground, might be the most intriguing of the three. At an elementary level, it captures some simple truths about accounting, or at least some simple statements we would like to be true. But as the complexities of the metaphor are explored, they reveal a variety of intriguing ontological issues that concern financial statements

Money n\u27 Motion - Born to be Wild

There are intriguing parallels between motoring and personal investing: the romance, the thrilling movement, and the freedom; the banality, the enervating repetition, and the entrapment; the subconsciously seductive appeal of crashes that ends it all. Consequently, there are intriguing parallels between the automobile and accounting, without which the activities of motoring and personal investing, respectively, would be severely attenuated, if they were possible at all. And there are intriguing parallels between popular media and accounting education, which are responsible for the enculturation processes that perpetuate the beliefs that in motoring and personal investing, by means of automobiles and accounting, we can be independent, we can be free, we can take control of our lives, and we can rise above the barriers of our social classes. The historian George W. Pierson\u27s mobility thesis explains these parallels. Motoring is not merely a fruitful metaphor for personal investing, automobiles for accounting, and popular media for accounting education. Motoring and personal investing are just two among many manifestations of the mobility which is characteristically American. Physically and financially, Americans need to be in motion