Parenting at Midnight: Measuring Parents\u27 Thoughts and Strategies to Help Young Children Sleep Through the Night

Throughout the night, brief periods of arousal are common and not necessarily indicative of problematic sleep. Awakening without an easy return to sleep (“night-waking”), however, can be problematic for parents and children alike. Approximately 30% of preschool-aged children wake at least once per night and require parental intervention (“help or assistance”). Although parents’ responses to children’s night-waking (i.e., parents’ night-waking strategies) can determine the course of night-waking over time, very little is known about night-waking strategy use among parents of preschool-aged children. The purpose of the present dissertation was to lay the foundation upon which a better understanding of the relationship of parenting to night-waking among preschool-aged children can be built. In order to accomplish this goal, four measures were created: the Children’s Night-waking Behaviour Scale (CNBS), the Night-waking Vignettes Scale (NVS), the Parents’ Night-waking Thoughts and Affect Questionnaire (PNTQ), and the Night-waking Strategies Scale (NSS). Rigorous measurement development protocols were followed. These measures, as well as parent-report measures of children’s night-waking and questionnaires used to assess construct validity, were completed by a sample of 203 mothers (M age = 32.4 years, SD =5.1) of preschool-aged children (M age = 3.4 years, SD = 1.0). All four measures displayed adequate to good reliability and promising evidence of convergent validity was observed. Significant associations between the measures and children’s night-waking were also observed. Following measurement development and validation, a series of multiple regressions were conducted to explore associations among the measures and identify areas for further research. In these regressions, mothers’ night-waking strategies (as measured by the NSS) were significantly predicted by children’s behaviour during night-wakings (as measured by the CNBS), mothers’ agreement with night-waking strategies (as measured by the NVS), and mothers’ thoughts and affect during night-waking episodes (as measured by the PNTQ). Clinical and research implications of these findings are discussed

Agreement with night-waking strategies among community mothers of preschool-aged children

Objective: To explore the night-waking schemas of mothers of preschool-aged children, using a new measure of agreement with night-waking strategies (Night-waking Vignettes Scale; NVS). MethodA community sample of 203 mothers (M age=32 years, SD=5.1) of 2- to 5-year-olds (M age=3.4 years, SD=1.0) provided demographic information and completed the NVS and measures of night-waking and general parenting behavior. Results: Few mothers endorsed strong agreement or disagreement with limit-setting, active comforting, or rewards; mothers generally disagreed with punishment. Significant associations between agreement with night-waking strategies, child sex, and maternal educational attainment were observed; only agreement with punishment was correlated with general parenting. Agreement with night-waking strategies differed across the night-waking behaviors depicted in the NVS vignettes. Agreement with limit-setting and agreement with active comforting were correlated with night-waking. Conclusions: Mothers may be ambivalent about common night-waking strategies. Night-waking schemas appear to be complex. © 2011 The Author. Published by Oxford University Press on behalf of the Society of Pediatric Psychology. All rights reserved

Cooperating in Video Games? Impossible! Undecidability of Team Multiplayer Games

We show the undecidability of whether a team has a forced win in a number of well known video games including: Team Fortress 2, Super Smash Brothers: Brawl, and Mario Kart.To do so, we give a simplification of the Team Computation Game [Hearn and Demaine, 2009] and use that to give an undecidable abstract game on graphs. This graph game framework better captures the geometry and common constraints in many games and is thus a powerful tool for showing their computational complexity

Concurrent associations among sleep problems, indicators of inadequate sleep, psychopathology, and shared risk factors in a population-based sample of healthy Ontario children

Objectives Examine the contribution of sleep problems and indicators of inadequate sleep to psychopathology among children after accounting for shared risk and comorbid psychopathology. Methods Secondary analyses of cross-sectional data on 4- to 11-year-old (N = 1,550) children without chronic illness or developmental delay or disability. Parents provided information about sleep problems, indicators of inadequate sleep, symptoms of psychopathology, and risk factors for psychopathology. Teachers provided information about indicators of inadequate sleep and symptoms of psychopathology. Results Adjusting for risk factors and comorbid psychopathology, sleeping more than other children was related to parent-rated aggression. Nightmares and trouble sleeping were related to parent-rated anxious/depressed mood. Sleep problems were not related to attention problems. Being overtired was related to parent- and teacher-rated psychopathology. Conclusions Relations among sleep problems, indicators of inadequate sleep, and psychopathology are complex; accounting for potential confounding variables and considering sleep variables separately may clarify these relations. © 2009 The Author. Published by Oxford University Press on behalf of the Society of Pediatric Psychology. All rights reserved

Evaluation of a Water Channel-Based Platform for Characterizing Aerostat Flight Dynamics: A Case Study on a Lighter-Than-Air Wind Energy System

Peer Reviewedhttps://deepblue.lib.umich.edu/bitstream/2027.42/140442/1/6.2014-2711.pd

Ecohydrologic separation of water between trees and streams in a Mediterranean climate

Water movement in upland humid watersheds from the soil surface to the stream is often described using the concept of translatory flow 1,2 , which assumes that water entering the soil as precipitation displaces the water that was present previously, pushing it deeper into the soil and eventually into the stream 2 . Within this framework, water at any soil depth is well mixed and plants extract the same water that eventually enters the stream. Here we present water-isotope data from various pools throughout a small watershed in the Cascade Mountains, Oregon, USA. Our data imply that a pool of tightly bound water that is retained in the soil and used by trees does not participate in translatory flow, mix with mobile water or enter the stream. Instead, water from initial rainfall events after rainless summers is locked into small pores with low matric potential until transpiration empties these pores during following dry summers. Winter rainfall does not displace this tightly bound water. As transpiration and stormflow are out of phase in the Mediterranean climate of our study site, two separate sets of water bodies with different isotopic characteristics exist in trees and streams. We conclude that complete mixing of water within the soil cannot be assumed for similar hydroclimatic regimes as has been done in the past 3,4 . Links between plant water-use (transpiration) and hydrology have been examined quantitatively since the paired-watershed studies in 1921 (ref. 5). These watershed-scale experiments clearly demonstrated links between vegetation and streamflow. However, the paired-watershed approach can only infer the mechanisms behind these vegetation-streamflow interaction

Active growth signaling promotes senescence and cancer cell sensitivity to CDK7 inhibition

Tumor growth is driven by continued cellular growth and proliferation. Cyclin-dependent kinase 7’s (CDK7) role in activating mitotic CDKs and global gene expression makes it therefore an attractive target for cancer therapies. However, what makes cancer cells particularly sensitive to CDK7 inhibition (CDK7i) remains unclear. Here, we address this question. We show that CDK7i, by samuraciclib, induces a permanent cell-cycle exit, known as senescence, without promoting DNA damage signaling or cell death. A chemogenetic genome-wide CRISPR knockout screen identified that active mTOR (mammalian target of rapamycin) signaling promotes samuraciclib-induced senescence. mTOR inhibition decreases samuraciclib sensitivity, and increased mTOR-dependent growth signaling correlates with sensitivity in cancer cell lines. Reverting a growth-promoting mutation in PIK3CA to wild type decreases sensitivity to CDK7i. Our work establishes that enhanced growth alone promotes CDK7i sensitivity, providing an explanation for why some cancers are more sensitive to CDK inhibition than normally growing cells

The impact of loco-regional recurrences on metastatic progression in early-stage breast cancer: a multistate model

To study whether the effects of prognostic factors associated with the occurrence of distant metastases (DM) at primary diagnosis change after the incidence of loco-regional recurrences (LRR) among women treated for invasive stage I or II breast cancer. The study population consisted of 3,601 women, enrolled in EORTC trials 10801, 10854, or 10902 treated for early-stage breast cancer. Data were analysed in a multivariate, multistate model by using multivariate Cox regression models, including a state-dependent covariate. The presence of a LRR in itself is a significant prognostic risk factor (HR: 3.64; 95%-CI: 2.02-6.5) for the occurrence of DM. Main prognostic risk factors for a DM are young age at diagnosis (</=40: HR: 1.79; 95%-CI: 1.28-2.51), larger tumour size (HR: 1.58; 95%-CI: 1.35-1.84) and node positivity (HR: 2.00; 95%-CI: 1.74-2.30). Adjuvant chemotherapy is protective for a DM (HR: 0.66; 95%-CI: 0.55-0.80). After the occurrence of a LRR the latter protective effect has disappeared (P = 0.009). The presence of LRR in itself is a significant risk factor for DM. For patients who are at risk of developing LRR, effective local control should be the main target of therapy