Efficacy of therapist-delivered transdiagnostic CBT for patients with persistent physical symptoms in secondary care: a randomised controlled trial

Background: Medically unexplained symptoms otherwise referred to as persistent physical symptoms (PPS) are debilitating to patients. As many specific PPS syndromes share common behavioural, cognitive, and affective influences, transdiagnostic treatments might be effective for this patient group. We evaluated the clinical efficacy and cost-effectiveness of a therapist-delivered, transdiagnostic cognitive behavioural intervention (TDT-CBT) plus (+) standard medical care (SMC) v. SMC alone for the treatment of patients with PPS in secondary medical care. Methods: A two-arm randomised controlled trial, with measurements taken at baseline and at 9, 20, 40- and 52-weeks post randomisation. The primary outcome measure was the Work and Social Adjustment Scale (WSAS) at 52 weeks. Secondary outcomes included mood (PHQ-9 and GAD-7), symptom severity (PHQ-15), global measure of change (CGI), and the Persistent Physical Symptoms Questionnaire (PPSQ). Results: We randomised 324 patients and 74% were followed up at 52 weeks. The difference between groups was not statistically significant for the primary outcome (WSAS at 52 weeks: estimated difference -1.48 points, 95% confidence interval from -3.44 to 0.48, p = 0.139). However, the results indicated that some secondary outcomes had a treatment effect in favour of TDT-CBT + SMC with three outcomes showing a statistically significant difference between groups. These were WSAS at 20 weeks (p = 0.016) at the end of treatment and the PHQ-15 (p = 0.013) and CGI at 52 weeks (p = 0.011). Conclusion: We have preliminary evidence that TDT-CBT + SMC may be helpful for people with a range of PPS. However, further study is required to maximise or maintain effects seen at end of treatment

The SAMI Galaxy Survey: Cubism and covariance, putting round pegs into square holes

We present a methodology for the regularization and combination of sparse sampled and irregularly gridded observations from fibre-optic multiobject integral field spectroscopy. The approach minimizes interpolation and retains image resolution on combining subpixel dithered data. We discuss the methodology in the context of the Sydney-AAO multiobject integral field spectrograph (SAMI) Galaxy Survey underway at the Anglo-Australian Telescope. The SAMI instrument uses 13 fibre bundles to perform high-multiplex integral field spectroscopy across a 1° diameter field of view. The SAMI Galaxy Survey is targeting ~3000 galaxies drawn from the full range of galaxy environments. We demonstrate the subcritical sampling of the seeing and incomplete fill factor for the integral field bundles results in only a 10 per cent degradation in the final image resolution recovered. We also implement a new methodology for tracking covariance between elements of the resulting data cubes which retains 90 per cent of the covariance information while incurring only a modest increase in the survey data volume

Development of a Halotolerant Community in the St. Lucia Estuary (South Africa) during a Hypersaline Phase

Background: The St. Lucia Estuary, Africa’s largest estuarine lake, is currently experiencing unprecedented freshwater deprivation which has resulted in a northward gradient of drought effects, with hypersaline conditions in its northern lakes. Methodology/Principal Findings: This study documents the changes that occurred in the biotic communities at False Bay from May 2010 to June 2011, in order to better understand ecosystem functioning in hypersaline habitats. Few zooplankton taxa were able to withstand the harsh environmental conditions during 2010. These were the flatworm Macrostomum sp., the harpacticoid copepod Cletocamptus confluens, the cyclopoid copepod Apocyclops cf. dengizicus and the ciliate Fabrea cf. salina. In addition to their exceptional salinity tolerance, they were involved in a remarkably simple food web. In June 2009, a bloom of an orange-pigmented cyanobacterium (Cyanothece sp.) was recorded in False Bay and persisted uninterruptedly for 18 months. Stable isotope analysis suggests that this cyanobacterium was the main prey item of F. cf. salina. This ciliate was then consumed by A. cf. dengizicus, which in turn was presumably consumed by flamingos as they flocked in the area when the copepods attained swarming densities. On the shore, cyanobacteria mats contributed to a population explosion of the staphylinid beetle Bledius pilicollis. Although zooplankton disappeared once salinities exceeded 130, many taxa are capable of producing spores or resting cysts to bridge harsh periods. The hypersaline community was disrupted by heavy summer rains in 2011, which alleviated drought conditions and resulted in a sharp increase in zooplankton stock an

Obese adults\u27 perceptions of news reporting on obesity: the panopticon and synopticon at work

News reporting, in channels such as broadcast and print media, on obesity as an issue has increased dramatically in the last decade. A qualitative study, in which we used in-depth interviews and thematic analysis, was undertaken to explore 142 obese individuals’ perceptions of, and responses to, news reporting about obesity. Participants believed that news reporting on obesity focused on personal responsibility and blame, and portrayed obese people as “freaks.” They described being portrayed as “enemies” of society who were rarely given a voice or identity in such news coverage unless they were seen to be succeeding at weight loss. They were also critical of the simplistic coverage of obesity, which was in contrast with their personal experiences of obesity as complex and difficult to address. Participants believed that obesity news reporting added to the discrimination they experienced. We consider how this news reporting may act as a form of “synoptical” social control, working in tandem with wider public health panoptical surveillance of obesity

The Gigaparsec WiggleZ Simulations: Characterising scale dependant bias and associated systematics in growth of structure measurements

We use the Gigaparsec WiggleZ (GiggleZ) simulations to characterise galaxy bias and its scale dependence for a range of redshifts and halo masses in a standard $\Lambda$LCDM cosmology. Assuming bias converges to a scale independent form at large scales, we develop a phenomenological model which fully expresses the mass and redshift dependence of bias and its scale dependence in real or redshift space. We then use this to illustrate how scale-dependent bias can systematically skew measurements of the growth-rate of cosmic structure obtained from redshift-space distortion measurements. When data is fit only to scales $k_{\rm max}{\le}0.1$ $[h^{-1} \rm{Mpc}]^{-1}$, we find that these effects are significant only for large biases ($b{\gtrsim}3$) at large redshifts ($z{\gtrsim}1$). However, when smaller scales are incorporated ($k_{\rm max}{\le}0.2$ $[h^{-1} \rm{Mpc}]^{-1}$) to increase measurement precision, the combination of reduced statistical uncertainty and increased scale dependent bias can result in highly significant systematics for most large halos across all redshifts. We identify several new interesting aspects of bias, including a significant large-scale bias boost for small halos at low-redshifts due to substructure effects ($\sim$20\% for Milky Way-like systems) and a nearly redshift-independent halo mass (corresponding to a redshift-space bias of ${\sim}1.5$) for which halo bias has little-or-no scale dependence on scales greater than $3$ $[h^{-1} {\rm Mpc}]$. This suggests an optimal strategy of targeting bias ${\sim}{1.5}$ systems for clustering studies which are dominated by systematic uncertainties in how observed halo (or galaxy) distributions map to their underlying mass distribution, such as cosmological measurements of neutrino masses. Code for generating our fitting formula is publicly available at http://gbpoole.github.io/Poole_2014a_code/ (Abridged)Comment: 17 Pages, 10 Figures, Accepted for publication in MNRA

Galaxy And Mass Assembly (GAMA): Testing galaxy formation models through the most massive galaxies in the Universe

We have analysed the growth of Brightest Group Galaxies and Brightest Cluster Galaxies (BGGs/BCGs) over the last 3 billion years using a large sample of 883 galaxies from the Galaxy And Mass Assembly survey. By comparing the stellar mass of BGGs and BCG

First light results from the Hermes spectrograph at the AAT

The High Efficiency and Resolution Multi Element Spectrograph, HERMES is an facility-class optical spectrograph for the AAT. It is designed primarily for Galactic Archeology [21], the first major attempt to create a detailed understanding of galaxy formation and evolution by studying the history of our own galaxy, the Milky Way. The goal of the GALAH survey is to reconstruct the mass assembly history of the of the Milky Way, through a detailed spatially tagged abundance study of one million stars. The spectrograph is based at the Anglo Australian Telescope (AAT) and is fed by the existing 2dF robotic fiber positioning system. The spectrograph uses VPH-gratings to achieve a spectral resolving power of 28,000 in standard mode and also provides a high-resolution mode ranging between 40,000 to 50,000 using a slit mask. The GALAH survey requires a SNR greater than 100 for a star brightness of V=14. The total spectral coverage of the four channels is about 100nm between 370 and 1000nm for up to 392 simultaneous targets within the 2 degree field of view. Hermes has been commissioned over 3 runs, during bright time in October, November and December 2013, in parallel with the beginning of the GALAH Pilot survey starting in November 2013. In this paper we present the first-light results from the commissioning run and the beginning of the GALAH Survey, including performance results such as throughput and resolution, as well as instrument reliability. We compare the abundance calculations from the pilot survey to those in the literature

The Sami Galaxy Survey: Toward a Unified Dynamical Scaling Relation for Galaxies of All Types

We take advantage of the first data from the Sydney-AAO Multi-object Integral field Galaxy Survey to investigate the relation between the kinematics of gas and stars, and stellar mass in a comprehensive sample of nearby galaxies. We find that all 235 objects in our sample, regardless of their morphology, lie on a tight relation linking stellar mass (M∗) to internal velocity quantified by the S0.5 parameter, which combines the contribution of both dispersion (σ) and rotational velocity (Vrot) to the dynamical support of a galaxy (S0.5 = √ 0.5 Vrot2 + σ2). Our results are independent of the baryonic component from which σ and V rot are estimated, as the S 0.5 of stars and gas agree remarkably well. This represents a significant improvement compared to the canonical M∗ versus Vrot and M∗ versus σ relations. Not only is no sample pruning necessary, but also stellar and gas kinematics can be used simultaneously, as the effect of asymmetric drift is taken into account once Vrot and σ are combined. Our findings illustrate how the combination of dispersion and rotational velocities for both gas and stars can provide us with a single dynamical scaling relation valid for galaxies of all morphologies across at least the stellar mass range 8.5 ⊙) < 11. Such relation appears to be more general and at least as tight as any other dynamical scaling relation, representing a unique tool for investigating the link between galaxy kinematics and baryonic content, and a less biased comparison with theoretical models