3,717 research outputs found
Ab initio parametrised model of strain-dependent solubility of H in alpha-iron
The calculated effects of interstitial hydrogen on the elastic properties of
alpha-iron from our earlier work are used to describe the H interactions with
homogeneous strain fields using ab initio methods. In particular we calculate
the H solublility in Fe subject to hydrostatic, uniaxial, and shear strain. For
comparison, these interactions are parametrised successfully using a simple
model with parameters entirely derived from ab initio methods. The results are
used to predict the solubility of H in spatially-varying elastic strain fields,
representative of realistic dislocations outside their core. We find a strong
directional dependence of the H-dislocation interaction, leading to strong
attraction of H by the axial strain components of edge dislocations and by
screw dislocations oriented along the critical slip direction. We
further find a H concentration enhancement around dislocation cores, consistent
with experimental observations.Comment: part 2/2 from splitting of 1009.3784 (first part was 1102.0187),
minor changes from previous version
On piezophase effects in mechanically loaded atomic scale Josephson junctions
The response of an intrinsic Josephson contact to externally applied stress
is considered within the framework of the dislocation-induced atomic scale
Josephson effect. The predicted quasi-periodic (Fraunhofer-like)stress-strain
and stress-current patterns should manifest themselves for experimentally
accessible values of applied stresses in intrinsically defected (e.g.,twinned)
crystals.Comment: REVTEX (epsf style), 2 EPS figure
Transition to 21st century socialism in the European Union
This paper attempts to outline the economic steps that would be necessary to convert a capitalist economy like the EU into a socialist one. We examine the issue in very concrete terms and propose specific policy measures. The measures we propose differ significantly from the tradition of 20th century European Social Democracy
Wisconsin’s Disaggregated Development and the Study of the Midwest
Understanding Wisconsin’s decentralized and greatly localized early development offers important clues for historians of later eras who are attempting to come to terms with the history of the Midwest as a region. The Fox River Valley is but one example of the divisions – economic and otherwise – that make the Midwestern states a patchwork of regions centered on places that might have little bearing to other locations within even their own state. This is both a challenge and an opportunity for historians of the Midwest, typically accustomed to state-based histories, to consider both the global and the intensely local in their work
Scaling Behaviour and Complexity of the Portevin-Le Chatelier Effect
The plastic deformation of dilute alloys is often accompanied by plastic
instabilities due to dynamic strain aging and dislocation interaction. The
repeated breakaway of dislocations from and their recapture by solute atoms
leads to stress serrations and localized strain in the strain controlled
tensile tests, known as the Portevin-Le Chatelier (PLC) effect. In this present
work, we analyse the stress time series data of the observed PLC effect in the
constant strain rate tensile tests on Al-2.5%Mg alloy for a wide range of
strain rates at room temperature. The scaling behaviour of the PLC effect was
studied using two complementary scaling analysis methods: the finite variance
scaling method and the diffusion entropy analysis. From these analyses we could
establish that in the entire span of strain rates, PLC effect showed Levy walk
property. Moreover, the multiscale entropy analysis is carried out on the
stress time series data observed during the PLC effect to quantify the
complexity of the distinct spatiotemporal dynamical regimes. It is shown that
for the static type C band, the entropy is very low for all the scales compared
to the hopping type B and the propagating type A bands. The results are
interpreted considering the time and length scales relevant to the effect.Comment: 35 pages, 6 figure
FGFR2 amplification in colorectal adenocarcinoma
FGFR2 is recurrently amplified in 5% of gastric cancers and 1%–4% of breast cancers; however, this molecular alteration has never been reported in a primary colorectal cancer specimen. Preclinical studies indicate that several FGFR tyrosine-kinase inhibitors (TKIs), such as AZD4547, have in vitro activity against the FGFR2-amplified colorectal cell line, NCI-H716. The efficacy of these inhibitors is currently under investigation in clinical trials for breast and gastric cancer. Thus, better characterizing colorectal tumors for FGFR2 amplification could identify a subset of patients who may benefit from FGFR TKI therapies. Here, we describe a novel FGFR2 amplification identified by clinical next-generation sequencing in a primary colorectal cancer. Further characterization of the tumor by immunohistochemistry showed neuroendocrine differentiation, similar to the reported properties of the NCI-H716 cell line. These findings demonstrate that the spectrum of potentially clinically actionable mutations detected by targeted clinical sequencing panels is not limited to only single-nucleotide polymorphisms and insertions/deletions but also to copy-number alterations.</jats:p
A new method for the spectroscopic identification of stellar non-radial pulsation modes. II. Mode identification of the Delta Scuti star FG Virginis
We present a mode identification based on new high-resolution time-series
spectra of the non-radially pulsating Delta Scuti star FG~Vir (HD 106384, V =
6.57, A5V). From 2002 February to June a global Delta Scuti Network (DSN)
campaign, utilizing high-resolution spectroscopy and simultaneous photometry
has been conducted for FG~Vir in order to provide a theoretical pulsation
model. In this campaign we have acquired 969 Echelle spectra covering 147 hours
at six observatories. The mode identification was carried out by analyzing line
profile variations by means of the Fourier parameter fit method, where the
observational Fourier parameters across the line are fitted with theoretical
values. This method is especially well suited for determining the azimuthal
order m of non-radial pulsation modes and thus complementary with the method of
Daszynska-Daszkiewicz (2002) which does best at identifying the degree l. 15
frequencies between 9.2 and 33.5 c/d were detected spectroscopically. We
determined the azimuthal order m of 12 modes and constrained their harmonic
degree l. Only modes of low degree (l <= 4) were detected, most of them having
axisymmetric character mainly due to the relatively low projected rotational
velocity of FG Vir. The detected non-axisymmetric modes have azimuthal orders
between -2 and 1. We derived an inclination of 19 degrees, which implies an
equatorial rotational rate of 66 km/s.Comment: 14 pages, 26 figure
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