48 research outputs found

    The Grizzly, November 5, 2015

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    Wellness Increases Accessibility to Students • Trending: Discounted Jerseys • U-Imagine to Host Annual Bear Pitch Competition • A New Take on an Old Genre • STAT: More Than Just an Acronym • Opinions: Students Who Go the Distance; Sicario • Field Hockey Set to Defend Centennial Conference Title • Battle in Gettysburghttps://digitalcommons.ursinus.edu/grizzlynews/1676/thumbnail.jp

    The Grizzly, October 22, 2015

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    New President on the Brock: Brock Blomberg Takes the Helm at Ursinus • Blomberg Installed as 17th President • Blomberg Begins New Era with Intellectual Discussions • Homecoming Court Crowned • 5 Questions with Brock • A Historic Moment Celebrated in a Historic Place • A Taste of the Workplace • Dr. Hess has Good Chemistry with Freshmen Students • Opinions: Should UC Ban Cigarettes?; New Film Green Inferno Rates 3 / 10 • Distance Doesn\u27t Matter: Two Women\u27s Soccer Players Come From Very Far Apart • Men\u27s and Women\u27s Soccer Look to End Seasons on a High Notehttps://digitalcommons.ursinus.edu/grizzlynews/1674/thumbnail.jp

    The Grizzly, October 29, 2015

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    SPINT Hosts Trick-or-Treating • Fall Foliage at Ursinus • Antisemitism Panel Seeks Nuance • HEART Lab Brings Promising Results • Harvest Festival Ends Sustainability Week • Rekindling the Lantern • A Poem a Day Keeps Writer\u27s Block Away • In the Voice of the Frog • Opinions: Voter Ambivalence is Harmful; Gun Control a Loaded Issue • Division III Sports Offer Big-Time Benefits to Ursinus Athletes • Men\u27s and Women\u27s Swimming Prepare for Start of Seasonhttps://digitalcommons.ursinus.edu/grizzlynews/1675/thumbnail.jp

    The Grizzly, September 10, 2015

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    Campus Adapts to Canvas Roll Out • Blomberg Spends Summer Traveling, Meeting with Alumni • New Greek Organizations Look to Form Chapters on Campus • Student Government Launches Free Textbook Pilot Program • Ursinus Songwriter Explores Human Nature Through Music • Mentors in Academics and Life: Ursinus Remembers Dr. Cameron and Dr. Hemphill • Theater Community Welcomes Performing Arts Scholar • Opinions: New Tips for a New Year at UC; Straight Outta Compton Rates 7 / 10 • Globetrotters: Men\u27s Basketball Competes in Europe • Bears Upset Millersville in Record Five Overtimeshttps://digitalcommons.ursinus.edu/grizzlynews/1669/thumbnail.jp

    The Grizzly, November 12, 2015

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    Highlighting a New Trend on Campus • Making Connections: Ursinus Prepares to Break Ground on a Structure Between Pfahler and Thomas • Acclaimed Literary Critic to Give Talk on Campus • Ursinus Brings Top Lawyer Aboard in New Position • International Perspective: How One Student Uses Dance to Connect Ethiopia and Ursinus • Can You Really Netflix and Chill Without Killing Your Grades? • Opinions: Are You a White Feminist?; Bridge of Spies • Defensive Lineman Unleashes Passion for Music • Field Hockey Upsets F&M for Titlehttps://digitalcommons.ursinus.edu/grizzlynews/1677/thumbnail.jp

    The Grizzly, November 19, 2015

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    On the Way to the Final Four • Watson Finalists Prepare for Next Steps • U-Imagine Center Offers First Course • Committee Searches for Violence Prevention Educator • International Perspective: Dealing With Graduation Concerns Abroad • Warming Up to the Challenge • Podcast Roars to Life • Preparing for Professional Life • Opinions: It\u27s On Us is Insufficient; Wellness Critics are Ill-Informed • New Era Begins for Women\u27s Basketball • Two Wrestlers Named Preseason All-Americans • Final Four Boundhttps://digitalcommons.ursinus.edu/grizzlynews/1678/thumbnail.jp

    Propulsion in cubomedusae : mechanisms and utility

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    © The Author(s), 2013. This article is distributed under the terms of the Creative Commons Attribution License. The definitive version was published in PLoS ONE 8 (2013): e56393, doi:10.1371/journal.pone.0056393.Evolutionary constraints which limit the forces produced during bell contractions of medusae affect the overall medusan morphospace such that jet propulsion is limited to only small medusae. Cubomedusae, which often possess large prolate bells and are thought to swim via jet propulsion, appear to violate the theoretical constraints which determine the medusan morphospace. To examine propulsion by cubomedusae, we quantified size related changes in wake dynamics, bell shape, swimming and turning kinematics of two species of cubomedusae, Chironex fleckeri and Chiropsella bronzie. During growth, these cubomedusae transitioned from using jet propulsion at smaller sizes to a rowing-jetting hybrid mode of propulsion at larger sizes. Simple modifications in the flexibility and kinematics of their velarium appeared to be sufficient to alter their propulsive mode. Turning occurs during both bell contraction and expansion and is achieved by generating asymmetric vortex structures during both stages of the swimming cycle. Swimming characteristics were considered in conjunction with the unique foraging strategy used by cubomedusae.This work was supported by an ONR MURI award (N000140810654) and National Science Foundation grant OCE 0623508 to JHC, SPC, JOD. And the work was supported by the Roger Williams University Foundation to Promote Scholarship

    Pan-cancer Alterations of the MYC Oncogene and Its Proximal Network across the Cancer Genome Atlas

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    Although theMYConcogene has been implicated incancer, a systematic assessment of alterations ofMYC, related transcription factors, and co-regulatoryproteins, forming the proximal MYC network (PMN),across human cancers is lacking. Using computa-tional approaches, we define genomic and proteo-mic features associated with MYC and the PMNacross the 33 cancers of The Cancer Genome Atlas.Pan-cancer, 28% of all samples had at least one ofthe MYC paralogs amplified. In contrast, the MYCantagonists MGA and MNT were the most frequentlymutated or deleted members, proposing a roleas tumor suppressors.MYCalterations were mutu-ally exclusive withPIK3CA,PTEN,APC,orBRAFalterations, suggesting that MYC is a distinct onco-genic driver. Expression analysis revealed MYC-associated pathways in tumor subtypes, such asimmune response and growth factor signaling; chro-matin, translation, and DNA replication/repair wereconserved pan-cancer. This analysis reveals insightsinto MYC biology and is a reference for biomarkersand therapeutics for cancers with alterations ofMYC or the PMN

    Genomic, Pathway Network, and Immunologic Features Distinguishing Squamous Carcinomas

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    This integrated, multiplatform PanCancer Atlas study co-mapped and identified distinguishing molecular features of squamous cell carcinomas (SCCs) from five sites associated with smokin
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