13 research outputs found

    Comparative analysis of overland flow models using finite volume schemes

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    In this paper attention is first focused on a comparative analysis of three hydraulic models for overland flow simulations. In particular, the overland flow was considered as a 2D unsteady flow and was mathematically described using three approaches (fully dynamic, diffusive and kinematic waves). Numerical results highlighted that the differences among the simulations were not very important when the simulations referred to commonly used ideal tests found in the literature in which the topography is reduced to plane surface. Significant differences were observed in more complicated tests for which only the fully dynamic model was able to provide a good prediction of the observed discharges and water depths. Then, attention is focused on the fully dynamic model and in particular on the analysis of two numerical schemes (TVD-MacCormack and HLL) and the influence of the grid size. Numerical tests carried out on irregular topography show that, as the grid size decreases, the performance of the HLL scheme becomes closer to that of the TVD-MacCormack scheme in shorter computational times at least for high rainfall intensity

    Dam breach modelling: influence on downstream water levels and a proposal of a physically based module for flood propagation software

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    The influence exerted by the method used for computing the dam breach hydrograph on the simulated maximum water levels throughout the downstream valley is essential for selecting a specific computing module to be implemented in the numerical codes used by practitioners. This module should be able to balance the need for a reasonable physical description of the phenomenon and, at the same time, limit as much as possible the maximum number of parameters. In order to feed a debate on this field, in this paper the performances of some parametric models used for the dam breach module implemented in the popular HEC-RAS software, and a simplified but physically based model have been analysed. The performances of the dam breach models have been assessed with reference to the historical event of the Big Bay dam, using both one-dimensional and two-dimensional (1-D and 2-D) flood propagation modelling. The results show that the physically based model considered here, without any operations of ad hoc calibration, has provided the best results in predicting computation of that event. Therefore, it may be proposed as a valid alternative to parametric models, which need the estimation of some parameters that can add further uncertainties in studies like these

    Comparing Different Modelling Strategies for the Estimation of Climate Change Effects on Urban Pluvial Flooding

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    In this paper, two different strategies are presented that allow for the assessment of the effects of climate change on urban pluvial flooding, in order to understand potentialities and limitations, advantages and drawbacks. The two strategies are hereby defined as “top-down” and “bottom-up”, according to the relative position of climate change modelling with respect to flood modelling (upstream for top-down, downstream for bottom-up). To provide a practical example, the two strategies are applied to a case study located in Naples, Italy. However, they can be successfully extended for the assessment of any potential impact of climate change in any location

    Role of FAP48 in HIV-associated lipodystrophy

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    The introduction of highly active antiretroviral therapies (HAART) has significantly changed the clinical course of HIV disease, with prolonged survival and better quality of life for HIV infected patients. However, this successful therapeutic advance has been partially marked by the development of serious long-term side effects including metabolic alterations, cardiovascular disease, kidney impairment, bone alterations and adipose tissue redistribution. This last phenomenon is currently indicated as HIV related lipodystrophy (Barbaro, 2006). Even if some studies suggested an independent role for HIV in the development of lipodystrophic phenotype, there is a widely accepted consensus that the risk to develop fat redistribution in HIV patients has to be mostly related to antiretroviral therapy. In order to investigate new pathways involved in the development of lipodystrophy, our group performed an array screening using two identical filter arrays with cDNAlabeled probes, generated from the adipose tissue of either HIV patients affected or not affected by lipodystrophy. Among the genes selected, we focused our attention on a recently described 48 kDa protein of 417 amino acids named FAP48. Our results suggest, using 3T3-L1-FAP48 stable clone, that FAP48 over-expression results in rapid NFAT dephosphorilatyon by activating CaN and in the increase of aP2 gene transcription, a gene expressed at the last phase of the adipocyte differentiation. These data support the role of Fap48 in the activation of adipocyte differentiation through a pathway involving NFAT. Moreover we evaluated the expression of PPARÎł and aP2 in 3T3-L1 FAP48pcDNA stably transfected cells treated with five antiretroviral drugs (Indinavir, Amprenavir, Efavirenz, Stavudine and Saquinavir), belonging to the three main classes of anti-HIV drugs, that were able, in our experimental model, to affect adipocyte differentiation (Esposito et al., 2009). We observed that cells treated with Saquinavir and Efavirenz, using 3T3-L1- FAP48 stable clone, are characterized by an increased expression of PPARÎł and aP2, during the 6 day time course, compared with the control cells. This evidence supports the hypothesis of a protective mechanism, that in 3T3L1 cells could counteract the toxicity of Efavirenz and Saquinavir or could be activated in presence of these drugs. Drawing from our experimental results it can be then postulated that this mechanism could work trough FAP48/ FBP52/Hsp90 pathway, suggesting this complex as a potential target for novel therapeutic approaches to the HAART related lipodystrophy in patients treated with regimen including Efavirenz and Saquinavir

    Advances in Flow Modeling for Water Resources and Hydrological Engineering

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    Surface and ground waters can be considered the main sources of water supply for agricultural, municipal, and industrial consumers. Over the centuries, the combination of both naturally occurring conditions and humanity’s actions has placed increasing pressure on these water resources. As an example, climate change and natural variability in the distribution and occurrence of water are among the natural driving forces that complicate the sustainable development of water resources. Recent advances in computer techniques have allowed scientists to develop complex models at different scales to support water-resource planning and management. The Special Issue “Advances in Flow Modeling for Water Resources and Hydrological Engineering” presents a collection of scientific contributions providing a sample of the state-of-the-art research in this field

    A comparative analysis of 3-D representations of urban flood map in virtual environments for hazard communication purposes

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    The flood hazard/risk maps do not allow a non-expert audience an immediate perception of the flooding impacts. Therefore, we need to modernize maps providing new communication approaches. In this context, 3-D representations of flood inundation through emerging formats in virtual and augmented realities may be considered as a powerful tool to engage users with flood hazards. The challenge of the research is to create a virtual 3-D environment aimed at supporting the public, practitioners and decision-makers in interpreting and understanding the impact of simulated flood hazards. For this purpose, the paper aims to perform a comparative analysis of two techniques to carry out the 3-D realistic visualizations of a flood map for representing a potential flooding of the Crati River, in the old town of Cosenza (South of Italy). The first approach develops a simple and quick workflow that provides an overall look at a neighbourhood level, but reveals some limits in water level visualization at the individual buildings scale. The second one requires additional terrestrial laser scanning (TLS) acquisition and overcomes some limits of the first approach, by providing a visual insight about water level close to building façades

    Performances of the New HEC-RAS Version 5 for 2-D Hydrodynamic-Based Rainfall-Runoff Simulations at Basin Scale: Comparison with a State-of-the Art Model

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    The Hydrologic Engineering Centre-River Analysis System (HEC-RAS), developed by the US Army Corps of Engineers, is one of the most known, analyzed and used model for flood mapping both in the scientific literature and in practice. In the recently released version (release 5.0.7), the HEC-RAS model has been enriched with novel modules, performing fully 2-D computations based on the 2-D fully dynamic equations as well as the 2-D diffusion wave equations; moreover the application of rainfall to each cell of the two-dimensional domain is now possible. Contrarily to the common applications for flood propagation in river reach, this specific module has never been analyzed in the literature. Therefore, the main purpose of this work is to assess the potential and the capabilities of the 2-D HEC-RAS model in rainfall-runoff simulations at the basin scale, comparing the results obtained using both the options (fully dynamic equations and diffusion wave equations) to the simulations obtained by using a 2-D fully dynamic model developed by the authors for research purposes. Both models have been tested in a small basin in Northern Italy to analyze the differences in terms of discharge hydrographs and flooded areas. The application of a criterion for hazard class mapping has shown significant variations between the two models. These results provide practical indications for the water engineering community in the innovative research field related to the use of 2-D SWEs at the basin scale

    Effects of DEM Depression Filling on River Drainage Patterns and Surface Runoff Generated by 2D Rain-on-Grid Scenarios

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    Topographic depressions in Digital Elevation Models (DEMs) have been traditionally seen as a feature to be removed as no outward flow direction is available to route and accumulate flows. Therefore, to simplify hydrologic analysis for practical purposes, the common approach treated all depressions in DEMs as artefacts and completely removed them in DEMs’ data preprocessing prior to modelling. However, the effects of depression filling on both the geomorphic structure of the river network and surface runoff is still not clear. The use of two-dimensional (2D) hydrodynamic modeling to track inundation patterns has the potential to provide novel point of views on this issue. Specifically, there is no need to remove topographic depression from DEM, as performed in the use of traditional methods for the automatic extraction of river networks, so that their effects can be directly taken into account in simulated drainage patterns and in the associated hydrologic response. The novelty introduced in this work is the evaluation of the effects of DEM depression filling on both the structure of the net-points characterizing the simulated networks and the hydrologic response of the watersheds to simplified rainfall scenarios. The results highlight how important these effects might be in practical applications, providing new insights in the field of watershed-scale modeling

    Using the present to estimate the future: A simplified approach for the quantification of climate change effects on urban flooding by scenario analysis

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    Understanding and modelling pluvial flood patterns is pivotal for the estimation of flood impacts in urban areas, especially in a climate change perspective. However, urban flood modelling under climate change conditions poses several challenges. On one hand, the identification and collection of climate change data suitable for flood-related evaluations requires consistent computational and scientific effort. On the other hand, large difficulties can arise in the reproduction of the rainfall-runoff transformation process in cases when only little information about the subsurface processes is known. In this perspective, a simplified approach is proposed to address the challenges regarding the quantitative estimation of climate change effects on urban flooding for real case applications. The approach is defined as “bottom-up” because climate change information is not included in flood modelling, but it is only invoked for the interpretation of results. In other words, the challenge faced in this work is the development of a modelling strategy that is expeditious, because it does not require flood simulations for future rainfall scenarios, but only under current climate conditions, thus reducing the overall computational effort; and it is flexible, because results can be easily updated once new climate change data, scenarios or methods become available, without the need of additional flood simulations. To simulate real case applications, the approach is tested for a scenario analysis, where different return periods and hyetograph shapes are used as input for urban inundation modelling in Naples, Italy. The approach can support public and private stakeholders, such as land administrators and water systems managers; moreover, it represents a valuable and effective basis for climate change risk communication strategies
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