How Well Can We Control Dyslipidemias Through Lifestyle Modifications?

The role for lifestyle modifications to correct dyslipidemia(s) is reviewed. Dietary composition is crucial. Replacing saturated fat with MUFA or n-6 PUFA lowers plasma low-density lipoproteins (LDL) cholesterol and ameliorates the LDL/HDL ratio. Replacing saturated fat with carbohydrates has diverging effects due to the heterogeneity of carbohydrate foods. Diets rich in refined carbohydrates increase fasting and postprandial triglycerides, whereas the consumption of fiber-rich, low GI foods lowers LDL cholesterol with no detrimental effects on triglycerides. The role of polyphenols is debated: available evidence suggests a lowering effect of polyphenol-rich foods on postprandial triglycerides. As for functional foods, health claims on a cholesterol lowering effect of psyllium, beta-glucans and phytosterols are accepted by regulatory agencies. The importance of alcohol intake, weight reduction, and physical activity is discussed. In conclusion, there is evidence that lifestyle affects plasma lipid. A multifactorial approach including multiple changes with additive effects is the best option. This may also ensure feasibility and durability. The traditional Mediterranean way of life can represent a useful model

Identifying fetal yawns based on temporal dynamics of mouth openings: A preterm neonate model using support vector machines (SVMs)

Fetal yawning is of interest because of its clinical, developmental and theoretical implications. However, the methodological challenges of identifying yawns from ultrasonographic scans have not been systematically addressed. We report two studies that examined the temporal dynamics of yawning in preterm neonates comparable in developmental level to fetuses observed in ultrasound studies (about 31 weeks PMA). In Study 1 we tested the reliability and construct validity of the only quantitative measure for identifying fetal yawns in the literature, by comparing its scores with a more detailed behavioral coding system (The System for Coding Perinatal Behavior, SCPB) adapted from the comprehensive, anatomically based Facial Action Coding System for Infants and Young Children (Baby FACS). The previously published measure yielded good reliability but poor specificity, resulting in over-representation of yawns. In Study 2 we developed and tested a new machine learning system based on support vector machines (SVM) for identifying yawns. The system displayed excellent specificity and sensitivity, proving it to be a reliable and valid tool for identifying yawns in fetuses and neonates. This achievement represents a first step towards a fully automated system for identifying yawns in the perinatal period.Fetal yawning is of interest because of its clinical, developmental and theoretical implications. However, the methodological challenges of identifying yawns from ultrasonographic scans have not been systematically addressed. We report two studies that examined the temporal dynamics of yawning in preterm neonates comparable in developmental level to fetuses observed in ultrasound studies (about 31 weeks PMA). In Study 1 we tested the reliability and construct validity of the only quantitative measure for identifying fetal yawns in the literature, by comparing its scores with a more detailed behavioral coding system (The System for Coding Perinatal Behavior, SCPB) adapted from the comprehensive, anatomically based Facial Action Coding System for Infants and Young Children (Baby FACS). The previously published measure yielded good reliability but poor specificity, resulting in over-representation of yawns. In Study 2 we developed and tested a new machine learning system based on support vector machines (SVM) for identifying yawns. The system displayed excellent specificity and sensitivity, proving it to be a reliable and valid tool for identifying yawns in fetuses and neonates. This achievement represents a first step towards a fully automated system for identifying yawns in the perinatal period

Fear of COVID-19, depression, anxiety, and their association with Internet addiction disorder in a sample of Italian students

Abstract Background The 2019 Coronavirus (COVID-19) pandemic has led to a worldwide lockdown which has obliged people to stay confined at home, often resulting in social distancing measures and isolation, which can lead to mental health problems as well as to specific Internet-use disorders. This study aims to investigate fear of COVID-19, anxiety, and depression symptoms, and their impact on Internet addiction disorder, modeled as intrapersonal conflicts and interpersonal conflicts, during the COVID-19 epidemic. Method An online questionnaire was administered to 454 Italian students during the first national lockdown. All the recruited participants completed measures including the Depression, Anxiety, and Stress (DASS-21 ), Fear of COVID-19, and Internet addiction . Results The results of the present study demonstrated that fear of COVID-19 was associated with Internet addiction disorder, and fear of COVID-19 mediated the relationship between anxiety and Internet addiction disorder. Finally, controlling for covariates (age and gender), fear of COVID-19 was linked to Internet addiction disorder. Limitations Limitations include the cross-sectional research design and reliance on data exclusively from Italy. Conclusions Results are discussed in the framework of the Interaction-Person-Affect-Cognition-Execution (I-PACE) conceptualization of affective and cognitive responses as strategies for explicating the psycho-pathology of excessive Internet use

I Look, You Smile: The First Mother–Child Communicative Interaction: A Longitudinal Study:

This article discusses the first development of communicative interaction between mother and child, by analyzing the connection between expression and smile. A total of 13 mother–child dyads, recruited at the moment of admission to hospital, participated in the study. Observations have been made when the children were 3, 6, and 9 months old. Mother and child were put in front of each other, and the mother was asked to play freely with her child using a set of toys. The sequential codification of the mother's and the child's behaviors (occurrence and duration) was encoded by two independent observers. Occurrences and durations were analyzed to verify the increase of the interactive dyadic exchange along the three follow-ups. The results highlight an increase in synchronic behaviors in the dyad as the child's age increases, showing the circularity of the dyadic interaction: Mothers increase the occurrences of contingent responses and children increase their competences regarding emotional regulations

Pro-Environmental Behaviors and Well-Being in Adolescence: The Mediating Role of Place Attachment

Adolescents represent the future generation, so it is important to pay attention to behaviors that involve them as actors in social activities and constitute the expression of an adequate growth path. Engaging in pro-environmental behaviors leads adolescents to do something good for themselves, for their own community, and for the place in which they live, and this type of conduct increases their levels of well-being and place attachment. This study examines the association between pro-environmental behavior and personal and social well-being in a sample of 1925 adolescents aged 14 to 20 years. Structural equation analyses showed a direct positive effect of pro-environmental behavior on personal and social well-being as well as place attachment. The latter partially mediated the relationship between pro-environmental behaviors and personal and social well-being. This study is significant in that it provides new data on how pro-environmental behaviors enhance adolescents’ personal and social well-being by potentially ensuring long-term benefits, thereby suggesting that it is important to stimulate, motivate, and recommend these kinds of action

Effects of wholegrain cereal foods on plasma short chain fatty acid concentrations in individuals with the metabolic syndrome

Short chain fatty acids (SCFAs) derived from dietary fiber fermentation by gut microbiota have been identified as one of the mechanisms behind the association between habitual whole-grain intake and a lower risk of cardiometabolic diseases. The aims of the present work are: (1) to evaluate whether a whole-grain wheat-based diet may increase SCFAs concentration, and (2) to identify possible associations between SCFAs and metabolic changes observed after the nutritional intervention

Dietary fibre as a unifying remedy for the whole spectrum of obesity-associated cardiovascular risk

Obesity is a pandemic carrying the heavy burden of multiple and serious co-morbidities including metabolic syndrome, type 2 diabetes and cardiovascular diseases. The pathophysiological processes leading to the accumulation of body fat slowly evolve to fat accumulation in other body compartments than subcutaneous tissue. This abnormal fat deposition determines insulin resistance which in turn causes blood glucose and lipid metabolism derangement, non-alcoholic fatty liver disease, hypertension, and metabolic syndrome. All these conditions contribute to increase the cardiovascular risk of obese people. Several randomized clinical trials demonstrated that moderate weight loss (5–10%) in obese patients improves obesity-related metabolic risk factors and coexisting disorders. Therefore, nutritional strategies able to facilitate weight management, and in the meantime positively influence obesity-associated cardiovascular risk factors, should be implemented. To this aim, a suitable option could be dietary fibres that may also act independently of weight loss. The present narrative review summarizes the current evidence about the effects of dietary fibres on weight management in obese people. Moreover, all of the different cardiovascular risk factors are individually considered and evidence on cardiovascular outcomes is summarized. We also describe the plausible mechanisms by which different dietary fibres could modulate cardio-metabolic risk factors. Overall, despite both epidemiological and intervention studies on weight loss that show statistically significant but negligible clinical effects, dietary fibres seem to have a beneficial impact on main pathophysiological pathways involved in cardiovascular risk (i.e., insulin resistance, renin-angiotensin, and sympathetic nervous systems). Although the evidence is not conclusive, this suggests that fibre would be a suitable option to counteract obesity-related cardio-metabolic diseases also independently of weight loss. However, evidence is not consistent for the different risk factors, with clear beneficial effects shown on blood glucose metabolism and Low Density Lipoprotein (LDL) cholesterol while there is fewer, and less consistent data shown on plasma triglyceride and blood pressure. Ascribing the beneficial effect of some foods (i.e., fruits and vegetables) solely to their fibre content requires more investigation on the pathophysiological role of other dietary components, such as polyphenols