Composición química-funcional de aceites de Terminalia catappa de diferentes variedades

This study aimed to extract and physical-chemically characterize Terminalia catappa L. kernel oil from purple (CR) and yellow (CA) varieties. Physical-chemical parameters, composition of fatty acids, nutritional quality indices, bioactive compounds and antioxidant capacity of both oil varieties were evaluated according to the literature. Both oils presented low levels of acidity and peroxides, besides the predominance of unsaturated fatty acids, ~63% of oleic and ~26% of linoleic acids, which influenced its nutritional indices. The CR oil variety exhibited a higher content in anthocyanin (18.3 ± 1.5 mg·100 g-1), ascorbic acid (68.4 ± 2.02 mg·100 g-1) and total polyphenol contents (152.3 ± 2.4 mg GAE·g-1), and a good antioxidant activity (38.6 ± 2.2 μg TE·g-1) determined by TEAC assay, when compared to the CA oil (p < 0.05). Therefore, the results confirm the importance of T. catappa as a lipid source for human consumption to be used in the development of food products.El objetivo de este estudio fue extraer y caracterizar físico-químicamente aceite de semilla de Terminalia catappa de las variedades violeta (CR) y amarilla (CA). Se evaluaron parámetros fisicoquímicos, composición de ácidos grasos, índices de calidad nutricional, compuestos bioactivos y capacidad antioxidante de ambas variedades de aceite de acuerdo con a la literatura. Como resultado, ambos aceites presentaron bajos niveles de acidez y peróxidos, y predominio de ácidos grasos insaturados, ~63% de ácido oleico y ~26% de ácido linoleico, lo cual influyó en su perfil nutricional. La variedad de aceite CR presentó un mayor contenido de antocianina (18,3 ± 1,5 mg·100 g-1), ácido ascórbico (68,4 ± 2,02 mg·100 g-1) y contenido total de polifenoles (152,3 ± 2,4 mg GAE·g-1), y una alta actividad antioxidante (38,6 ± 2,2 μg TE·g-1) determinado por ensayo TEAC, en comparación con el aceite CA (p<0.05). En conclusión, los resultados presentados refuerzan la importancia de T. catappa como fuente de lípidos para la ingesta humana y para su uso en el desarrollo de productos alimenticios

Chemical-functional composition of Terminalia catappa oils from different varieties

This study aimed to extract and physical-chemically characterize Terminalia catappa L. kernel oil from purple (CR) and yellow (CA) varieties. Physical-chemical parameters, composition of fatty acids, nutritional quality indices, bioactive compounds and antioxidant capacity of both oil varieties were evaluated according to the literature. Both oils presented low levels of acidity and peroxides, besides the predominance of unsaturated fatty acids, ~63% of oleic and ~26% of linoleic acids, which influenced its nutritional indices. The CR oil variety exhibited a higher content in anthocyanin (18.3 ± 1.5 mg·100 g-1), ascorbic acid (68.4 ± 2.02 mg·100 g-1) and total polyphenol contents (152.3 ± 2.4 mg GAE·g-1), and a good antioxidant activity (38.6 ± 2.2 μg TE·g-1) determined by TEAC assay, when compared to the CA oil (p &lt; 0.05). Therefore, the results confirm the importance of T. catappa as a lipid source for human consumption to be used in the development of food products.</jats:p

Sera from chronic chagasic patients depress cardiac electrogenesis and conduction

We report results obtained with sera from 58 chronic chagasic patients that were evaluated for effects on heart rate and atrioventricular (AV) conduction in isolated rabbit hearts and screened for the presence of muscarinic and beta-adrenergic activity. We show that sera from 26 patients decreased heart rate, while 10 increased it and 22 had no effect. Additionally, sera from 20 of the 58 patients blocked AV conduction. Muscarinic activation seems to be involved in both effects, but is not the only mechanism, since atropine did not antagonize the decrease in heart rate in 23% of sera or AV block in 40%. Sera from patients with complex arrhythmias were significantly more effective in depressing both heart rate and AV conduction. Sera that induce increases in heart rate seem to operate exclusively through beta-adrenergic activation. Two of these sera, evaluated with respect to intercellular communication in primary cultures of embryonic cardiomyocytes were able to block gap junction conductance evaluated by a dye injection technique after 24-h exposure. The mechanisms underlying this uncoupling effect are currently being investigated