‘Don’t be a Zombie’: Deep Ecology and Zombie Misanthropy

This article examines the waysin which the Gothic imagination has been used to convey the message of environmentalism, looking specifically at attempts to curb population growth, such as the video ‘Zombie Overpopulation’, produced by Population Matters, and the history of such thought, from Thomas Malthus onwards. Through an analysis of horror fiction, including the writing of the notoriously misanthropic H. P. Lovecraft, it questions if it is possible to develop an aesthetics and attitude of environmental conservation that does not have to resort to a Gothic vision of fear and loathing of humankind. It draws on the ideas of Timothy Morton, particularly Dark Ecology (2016), to contend with the very real possibility of falling into nihilism and hopelessness in the face of the destruction of the natural world, and the liability of the human race, despite individual efforts towards co-existence. It examines cases of such despair, such as the diaries of Columbine shooter Eric Harris, whose extreme contempt for humanity spilled over into deadly violence. Lovecraft writes in ‘The Call of Cthulhu’ (1928) of a ‘bland optimism’ as the only alternative to nihilistic horror in the face of forces larger than ourselves, referring to humanity as a whole. Pointing to Morton, and to Donna Haraway’s notion of the ‘Cthuluscene’, this article argues that radical empathy and shared kinship might instead point the way towards the urgent change that is needed

Exploring Canadian Echinoderm Diversity through DNA Barcodes

Funding: This research was funded, in part, by the Natural Sciences and Engineering Research Council (NSERC) through a Discovery Grant to PDNH and a postgraduate scholarship to EAC. Sequence analysis was enabled by funding from the government of Canada through Genome Canada and the Ontario Genomics Institute in support of the International Barcode of Life Project (OGI-036). The funders had no role in study design, data collection and analysis, decision to publish, or preparation of the manuscript. Acknowledgments We thank Bridgette Clarkston, Christina Carr, Claudia Hand, Jeremy deWaard, Jim Boutillier, Katy Hind, Robert Frank, Sandra McCubbin, Tanya Brown, Tom Sheldon, and Victoria Frank for contributing specimens and aiding in collections. Kelly Sendall kindly provided access to the echinoderm collections at the Royal British Columbia Museum while we deeply appreciate the help that Chris Mah, Melissa Frey, and Phil Lambert provided with identifications. We also thank staff at the Canadian Centre for DNA Barcoding in the CBG for their aid in sequence acquisition. Lastly, we thank O.S. Klanten and two anonymous reviewers for their helpful suggestions on earlier versions of this manuscript.Peer reviewedPublisher PD

Changes in internal states across the binge–vomit cycle in bulimia nervosa

While there is considerable evidence that bulimic behaviors serve the function of modifying internal states (e.g., satiety, mood), there is less clarity over the roles of the different behaviors across the binge-purge cycle. The present study examines the impact of bingeing and vomiting upon these internal states at different time points, and evaluates the potential reinforcement of those behaviors by the changes in internal states. Twenty-three women with diagnoses of bulimia nervosa completed a diary of all binge-vomit episodes over the course of 7 days, rating their internal states (satiety, negative mood, positive mood) at four time points during each episode. There were substantial changes across the cycle in levels of hunger, fullness, guilt/shame, anxiety/worry, and happiness/relief, but not in other states. The changes indicate that the binge-vomit cycle is maintained by the effects of both behaviors, but that the vomiting behavior evokes the strongest pattern of reinforcement. Further research is needed to determine the levels of internal states during the binge itself

Cartoons vs. manga movies : a brief history of anime in the UK

This paper has as main objective to explore, adopting a historical and critical perspective, the release of film and anime TV in UK. This would be a first step towards the studio of the peculiar implementation of manganime Culture in Britain. Compared with other European countries, UK has shown to be slower and even reluctant in importing Japanese television products. Thus, while major markets of anime such as France, Italy or Spain expanded considerably during 1975-1995 period, in a recurrent synergy of television markets, and technological publishing, the implantation of the principal channel (televised anime) in UK has been irregular and unstable. Even today, the catalogue of broadcasting anime is limited to some high success movies, late night television on thematic channels and quite recently, video-on-demand services (Netflix). The offer cannot be compare in importance and diversity to other European countries. This fact, far from being anecdotal, has had an impact on the subsequent implantation of media Japanese cultures such as manga, anime, video games and cosplay. What can be the reason of this irregular development of Japanese visual culture in United Kingdom? Characteristic having the television market and / or the UK audience? Main hypothesis in relation to these issues can be considered to be of sociological character, but are reflected in the idiosyncrasies of British television culture and production system. Thus, compared to other Western markets (including the US) which saw the opportunity to purchase economic products for children’s television audiences in the late 70s and early 80s, the British ‘telly’ already offered a broad catalogue (Roobarb, Super Ted, Danger Mouse, etc. ...). The only exception to this children’s ‘made in Britain’ programming was the co-production model. This caused a leak of few products that were not even considered as “Japanese” (Seven Cities of Gold, Godzilla) but mere ‘cartoons’. This competition with the British children production as well as the wide catalogue of other forms of British Popular Culture would explain why the film, domestic video and later adults programming would be the marginal routes of entry for manganime

Glycogen Content Regulates Peroxisome Proliferator Activated Receptor-∂ (PPAR-∂) Activity in Rat Skeletal Muscle

Performing exercise in a glycogen depleted state increases skeletal muscle lipid utilization and the transcription of genes regulating mitochondrial β-oxidation. Potential candidates for glycogen-mediated metabolic adaptation are the peroxisome proliferator activated receptor (PPAR) coactivator-1α (PGC-1α) and the transcription factor/nuclear receptor PPAR-∂. It was therefore the aim of the present study to examine whether acute exercise with or without glycogen manipulation affects PGC-1α and PPAR-∂ function in rodent skeletal muscle. Twenty female Wistar rats were randomly assigned to 5 experimental groups (n = 4): control [CON]; normal glycogen control [NG-C]; normal glycogen exercise [NG-E]; low glycogen control [LG-C]; and low glycogen exercise [LG-E]). Gastrocnemius (GTN) muscles were collected immediately following exercise and analyzed for glycogen content, PPAR-∂ activity via chromatin immunoprecipitation (ChIP) assays, AMPK α1/α2 kinase activity, and the localization of AMPK and PGC-1α. Exercise reduced muscle glycogen by 47 and 75% relative to CON in the NG-E and LG-E groups, respectively. Exercise that started with low glycogen (LG-E) finished with higher AMPK-α2 activity (147%, p<0.05), nuclear AMPK-α2 and PGC-1α, but no difference in AMPK-α1 activity compared to CON. In addition, PPAR-∂ binding to the CPT1 promoter was significantly increased only in the LG-E group. Finally, cell reporter studies in contracting C2C12 myotubes indicated that PPAR-∂ activity following contraction is sensitive to glucose availability, providing mechanistic insight into the association between PPAR-∂ and glycogen content/substrate availability. The present study is the first to examine PPAR-∂ activity in skeletal muscle in response to an acute bout of endurance exercise. Our data would suggest that a factor associated with muscle contraction and/or glycogen depletion activates PPAR-∂ and initiates AMPK translocation in skeletal muscle in response to exercise