5 research outputs found
<a name="top"></a>Levantamento soroepidemiol贸gico de leptospirose em trabalhadores do servi莽o de saneamento ambiental em localidade urbana da regi茫o sul do Brasil
Infecci贸n inducida en el roedor selv谩tico Dasyprocta leporina (Rodentia: Dasyproctidae), con huevos larvados de Lagochilascaris minor (Nematoda: Ascarididae) Induced infection in the wild rodent Dasyprocta leporina (Rodentia: Dasyproctidae) with larval eggs of Lagochilascaris minor (Nematoda: Ascarididae)
Ejemplares de Dasyprocta leporina Linnaeus, 1758 fueron criados alejados de su ambiente natural. A los 3 贸 4 meses de edad, se los inocul贸 por v铆a oral con huevos de Lagochilascaris minor Leiper, 1909 obtenidos de una paciente nativa. Los huevos se los incub贸 por m谩s de 80 dias, para que de ellos fuese posible obtener por compresi贸n mec谩nica, larvas que se mantuviesen vivas en medio acuoso por 48 horas o m谩s. Sacrificados los animales a los 14 贸 46 dias posteriores a la infecci贸n, se hallaron en los m煤sculos esquel茅ticos larvas ovilladas dentro de n贸dulos inflamatorios, los cuales no presentaban reacci贸n a cuerpo extra帽o, abscedaci贸n o calcificaci贸n. El desarollo de los n贸dulos no parec铆a afectar la normalidad de los hospedadores. Las larvas obtenidas eran similares a las descritas por SPRENT como de tercer estadio para estos helmintos. Ratones blancos infectados con material similar, no presentaron n贸dulos en sus m煤sculos ni se pudo recuperar de sus tejidos larva alguna. Por los hallazgos obtenidos con la infecci贸n de estos animales, se postula que el helminto no posee ciclo pulmonar y que su desarrollo requiere de un hospedador intermediario.<br>Specimens of Dasyprocta leporina (Linnaeus, 1758) were raised out their natural environment. At three to four months of age they were orally inoculated with Lagochilascaris minor (Leiper, 1909) eggs obtained from a native patient. The eggs were incubated for more than 80 days so that it was possible to obtain, by mechanical compression, larvae that could be maintained alive in liquid medium for 48 hours or more. The animals were sacrificed 14-46 days after infection and tangled larva in inflammatory nodules were found in skeletal muscle without foreign body reaction, abscess formation or calcification. The development of the nodules did not seem to affect the hosts. The larvae obtained were similar to those described by SPRENT as the third stage of these helminths. When white mice were inoculated with similar material it was not possible to recuperate larva from their tissues nor were nodules found. Based on these results it is postulated that the helminth does not present a pulmonary cycle and that its development requires an intermediary host