Electronic Transport Properties or Ensembles of Perylene-Substituted Poly-isocyanopeptide Arrays

Contains fulltext : 72261.pdf (publisher's version ) (Closed access)9 p

Functional biohybrid amphiphiles

Contains fulltext : 35856.pdf (publisher's version ) (Open Access

Clustered nanocarriers: the effect of size on the clustering of CCMV virus-like particles with soft macromolecules

Virus-like particles (VLP) could enable a wide variety of biomedical applications in therapy, drug delivery, and imaging. They are biocompatible and can be self-assembled into larger structured materials for additional functionality and potentially better biodistribution, which is still a challenging aspect. Here we investigate the role of the VLPs size and resulting Caspar Klug symmetry in forming clusters out of these building blocks, showing that the onset point for clustering is determined by steric considerations of the binding site and binding agent. The clustering is independent of cargo and the data suggests that rotational symmetry in the T = 3 capsid allows for hexagonal close packed structures, whereas the T = 1 capsid that lacks a six-fold and twofold rotational axis does not show such organization

Construction of functional porphyrin polystyrene nano-architectures by ATRP

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Donor leukocyte infusions are effective in relapsed multiple myeloma after allogeneic bone marrow transplantation

Contains fulltext : 25674___.PDF (publisher's version ) (Open Access

Complex nanostructures from biohybrid block copolymers

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A virus-based single enzyme nanoreactor

Contains fulltext : 35237.pdf (publisher's version ) (Open Access

Stereoselection in the formation and folding of beta-helical polysocyanopeptides

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Self-assembled Architectures from Biohybrid Triblock Copolymers

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Virus-based nanocarriers for drug delivery

New nanocarrier platforms based on natural biological building blocks offer great promises in revolutionalizing medicine. The usage of specific protein cage structures: virus-like particles (VLPs) for drug packaging and targetted delivery is summarized here. Versatile chemical and genetic modifications on the outer surfaces and inner cavities of VLPs facilitate the preparation of new materials that could meet the biocompatibility, solubility and high uptake efficiency requirements for drug delivery. A full evaluation on the toxicity, bio-distribution and immunology of these materials are envisaged to boost their application potentials