Vida de agricultoras e histórias de documentos no Sertão Central de Pernambuco.

O artigo enfoca como as mulheres agricultoras, ao terem acesso a direitos sociais, especialmente à Previdência Social, lidam com a normatização e a regulamentação dos processos de nascimento, envelhecimento e morte. O objetivo é analisar as dificuldades e as estratégias que as mulheres utilizam para cumprirem as exigências legais de comprovação do trabalho na agricultura familiar através de documentos civis e profissionais. A pesquisa foi realizada nos municípios de Santa Cruz da Baixa Verde e Triunfo, situados no Sertão de Pernambuco, Nordeste do Brasil. A ausência de documentos é reveladora dos parâmetros de modernidade instaurados no país e deve ser entendida à luz das intersecções de gênero, classe, raça, etnia e critérios geopolíticos

Is the Eye an Extension of the Brain in Central Nervous System Disease?

Since 1950, global average life expectancy has been steadily increasing at a rate of more than 3 years per decade (with the exception of the 1990s), with accompanying growth in age-related neurodegenerative diseases, such as Alzheimer's (AD), Parkinson's (PD), amyotrophic lateral sclerosis (ALS), multiple sclerosis (MS), and stroke. The limited capacity of self-repair of the adult mammalian central nervous system (CNS) and the general lack of preventive and restorative treatments for these conditions lead to progressive debilitation and eventually death. Not only does this result in a diminished quality of life for patients (and their families) but also impacts society by placing tremendous demands on social welfare and health systems. How to “ensure healthy lives and promote well-being for all at all ages,” one of the Sustainable Development Goals for 2030, adopted by the United Nations General Assembly, is thus a challenge to be tackled by the next generation of researchers, clinicians, and policy makers

Exposure to the complement C5b-9 complex sensitizes 661W photoreceptor cells to both apoptosis and necroptosis.

The loss of photoreceptors is the defining characteristic of many retinal degenerative diseases, but the mechanisms that regulate photoreceptor cell death are not fully understood. Here we have used the 661W cone photoreceptor cell line to ask whether exposure to the terminal complement complex C5b-9 induces cell death and/or modulates the sensitivity of these cells to other cellular stressors. 661W cone photoreceptors were exposed to complete normal human serum following antibody blockade of CD59. Apoptosis induction was assessed morphologically, by flow cytometry, and on western blotting by probing for cleaved PARP and activated caspase-3. Necroptosis was assessed by flow cytometry and Sirtuin 2 inhibition using 2-cyano-3-[5-(2,5-dichlorophenyl)-2-furyl]-N-5-quinolinylacrylamide (AGK2). The sensitivity of 661W cells to ionomycin, staurosporine, peroxide and chelerythrine was also investigated, with or without prior formation of C5b-9. 661W cells underwent apoptotic cell death following exposure to C5b-9, as judged by poly(ADP-ribose) polymerase 1 cleavage and activation of caspase-3. We also observed apoptotic cell death in response to staurosporine, but 661W cells were resistant to both ionomycin and peroxide. Interestingly, C5b-9 significantly increased 661W sensitivity to staurosporine-induced apoptosis and necroptosis. These studies show that low levels of C5b-9 on 661W cells can induce apoptosis, and that C5b-9 specifically sensitizes 661W cells to certain apoptotic and necroptotic pathways. Our observations provide new insight into the potential role of the complement system in photoreceptor loss, with implications for the molecular aetiology of retinal disease

Software-defined networking: guidelines for experimentation and validation in large-scale real world scenarios

Part 1: IIVC WorkshopInternational audienceThis article thoroughly details large-scale real world experiments using Software-Defined Networking in the testbed setup. More precisely, it provides a description of the foundation technology behind these experiments, which in turn is focused around OpenFlow and on the OFELIA testbed. In this testbed preliminary experiments were performed in order to tune up settings and procedures, analysing the encountered problems and their respective solutions. A methodology consisting of five large-scale experiments is proposed in order to properly validate and improve the evaluation techniques used in OpenFlow scenarios

Small-sample corrections for score tests in Birnbaum-Saunders regressions

In this paper we deal with the issue of performing accurate small-sample inference in the Birnbaum-Saunders regression model, which can be useful for modeling lifetime or reliability data. We derive a Bartlett-type correction for the score test and numerically compare the corrected test with the usual score test, the likelihood ratio test and its Bartlett-corrected version. Our simulation results suggest that the corrected test we propose is more reliable than the other tests.Comment: To appear in the Communications in Statistics - Theory and Methods, http://www.informaworld.com/smpp/title~content=t71359723

Atributos químicos no perfil de solos cultivados com bananeira sob irrigação, no Projeto Formoso, Bom Jesus da Lapa, Bahia.

A utilização de solos de baixa fertilidade e a não manutenção de níveis adequados de nutrientes durante o ciclo da bananeira são fatores responsáveis pela baixa produtividade da cultura. Estudos sobre extração de nutrientes pela bananeira indicam que o potássio e o nitrogênio são os mais absorvidos pela planta, seguidos por cálcio, magnésio, enxofre e fósforo. Embora a bananeira necessite de grande quantidade de nutrientes, 66% da sua massa vegetativa é devolvida ao solo, na forma de pseudocaules, folhas e rizoma, portanto, uma recuperação significativa da quantidade de nutrientes, em razão da ciclagem dos mesmos. A bananeira é cultivada e se desenvolve em diversos tipos de solos, sendo que alguns apresentam limitações como baixa capacidade de troca catiônica (CTC) e saturação por bases (V%), alta acidez, baixo armazenamento de água e nutrientes, alto teor de argila 2:1, desbalanço entre cátions e outras. Contudo, essas áreas têm sido utilizadas com aplicação de diversas práticas de manejo visando reduzir essas limitações. Amostras em quatro perfis de diferentes solos cultivados com bananeira, sob irrigação, no Projeto Formoso, em Bom Jesus da Lapa-BA, classificados como Neossolo Quartzarênico (NQ), Latossolo Vermelho-Amarelo distrófico (LVAd), Argissolo Vermelho-Amarelo distrófico (PVAd) e Argissolo Vermelho-Amarelo eutrófico (PVAe) foram coletadas. As profundidades de amostragem foram definidas com base nas observações morfológicas (cor, textura e estrutura) dos perfis a campo e/ou na separação dos horizontes dos referidos solos. Na parte central de cada horizonte foram coletadas amostras de solo para determinação do pH em água, P, K, Ca, Mg, H+Al, soma de bases (SB), capacidade de troca catiônica (CTC), saturação por bases (V), matéria orgânica e microelementos (B, Zn, Cr, Ni, Cd, Pb e Hg).bitstream/item/87522/1/Id25348ALBorges.pdfDisponível em: Acesso em: 08 jan. 2009